A buoyant pool lounge chair frame and buoyant pool lounge chair using the same are disclosed. In one embodiment of the buoyant pool lounge chair for supporting a person while the buoyant pool chair is floating in water, frame members collectively form an open chair frame including a back frame and leg frame pivotally coupled thereto. Buoyant cushions are attached to the frame members to form a chair seat, a backrest, and a leg rest. A pair of rear pivotal coupling and clutch assemblies are coupled to the seat frame and to the back frame to adjust and fix the angle of recline of the back frame relative to the seat frame. Similarly, a pair of front pivotal coupling and clutch assemblies coupled to the leg frame and to the back frame to adjust and fix the angle of extension of the leg frame relative to the seat frame.

Methods for a cell-based assay for Botulinum neurotoxin are provided in which a transfected cell that produces a reporting peptide is contacted with a Botulinum neurotoxin in media having a sub-physiological osmolarity and a temperature that is above physiological temperature. This combination provides an unexpected synergistic effect in reducing the EC.sub.50 of the cell-based assay relative to an analogous cell-based assay performed at physiological osmolarity and temperature.

Light weight, easily stowed in small spaces inflatable chairs, pads, and flotation devices all from a relatively simple combination of at least two inflatable drop stitch panels which can be held in position relative to each other by use of straps, or in other embodiments, by additional inflatable side panels which provide arms and support to hold the chair upright on the ground. Simple hinges can be used to connect the panels together in desired configurations, either as fixed deployments or as adjustable and convertible deployments, where in one deployment, the panels for a chair, and in another, a flat pad, which can be used as a float or as a ground pad for camping.

A buoyant pool lounge chair is disclosed. In one embodiment of the buoyant pool lounge chair, frame members collectively form an open chair frame with buoyant cushions forming a chair seat and a backrest as well as a left arm rest and a right arm rest. The left arm rest and the right arm rest are each intersected by a cup holder. A recess in the cup holder has a forward tilt relative to a horizontal axis having an angle between approximately 20 degrees and approximately 40 degrees toward the front end of the buoyant pool lounge chair. In operation, when the buoyant pool lounge chair is supporting a person while the buoyant pool chair is floating in water, the forward tilt of the cup holder provides a compensating-leveling mechanism that mitigates spilling of liquid in the cup when the cup is placed within the cup holder.

A mat comprising an array of elongated buoyant elements enclosed in a casing or cover that may be waterproof or porous. The mat may be readily rolled into a cylindrical shape up for purposes of transportation and storage. A pillow may be removably encased in a pocket in the mat, and the pillow may be removable as desired. The pillow may be inflatable, whereby the user may select the extent of inflation (i.e., the hardness of the pillow) in order to provide a desired level of comfort.

An adjustable seat for a flotation device includes a seat member made of flexible material attached to, surrounded by, and depending from the flotation device, said seat having two apertures therein for receipt of the legs of a child. A matable connector attached to the flotation device and the seat member means permits the adjustment of the shape and relative depth of the seat member to accommodate children of different sizes.

A floatation mattress assembly for sleeping upon or floating in a body of water includes a mat that is comprised of a resiliently compressible material for sleeping upon. The mat is comprised of a buoyant material to float on a body of water. The mat is structured to have the ornamental appearance of a flip flop article of footwear. A first tube is pivotally coupled to the mat, and the first tube is positionable in a deployed position or a stored position. A second tube is coupled to the first tube and slidably extends through the mat. Thus, the first and second tubes have the ornamental appearance of foot straps on the flip flop article of footwear. A net is removably attached to each of the first and second tubes. The net forms a hemispherical dome over the mat when the first tube is positioned in the deployed position.

A submergible furniture is disclosed. Said submergible furniture comprises a threaded plugs, an outer shell and an internal cavity is configured to be partially submerged in a external body of liquid having a external liquid level. Said internal cavity is sealed by said outer shell and said threaded plugs. Said internal cavity comprises a gas portion and a liquid portion. Said liquid portion comprises an internal liquid level. Said submergible furniture is configured to be partially submerged in a external body of liquid. Said internal liquid level is higher than said external liquid level. Said internal cavity is selectively sealed with said threaded plugs. Said threaded plugs comprises a female plug portion and a male plug portion. Said female plug portion is welded into a portion of said outer shell. Said female plug portion is plastic welded into a portion of said outer shell.

A saddle for an aquatic board is disclosed. The saddle is equipped with a strap or straps and/or edge wise clamps, or other suitably firm fastener, to engage and maintain position on the aquatic board positioned beneath the saddle. A user can then stand on the board and squeeze the saddle between their knees and ankles and maintain an enhanced balance on the board or, if fatigued, can sit or kneel alongside or on the saddle and paddle/ride from a seated or kneeling position. The saddle may be inflatable or solid and may include an inner void for storage for personal effects or equipment. The saddle may further include a speaker, cup holder, handles, or other optional features.

The invention disclosed in this application is a floatation device for infants and small children combined with an exercise device for their parent. The device is designed to allow the child to be in the swimming pool with their parent with only a small part or none of the child to actually be in contact with the water. The invention consists of a seat for the child integrated into a floatation device. The child's seat will swivel to allow for the child to be facing in various directions while on the floatation device. Sections of the seat are removable so that the child may dangle their legs into the water while affixed in the seat. The floatation part of the invention is similar in size and shape to an adult swimming kickboard and can be utilized as such with a child either in the seat or not.