This nitrogen recovery method is for causing nitrifying bacteria to decompose an ammonia component in an ammonia-containing gas, and recovering a nitrogen component contained in ammonia as an ammonia gas decomposition product, involving: supplying circulating water to a microorganism decomposition tank retaining a nitrifying bacterium carrier carrying nitrifying bacteria to maintain the carrier wet; passing ammonia-containing gas through the carrier in the wet state in an oxygen-containing atmosphere; dissolving an ammonia component in the ammonia-containing gas in the circulating water, together with an ammonia gas decomposition product produced by the nitrifying bacteria, to continue decomposing the ammonia-containing gas while the decomposition product is accumulated in the circulating water; and collecting all or a portion of the circulating water to recover the ammonia gas decomposition product, when the concentration of nitrate ion as an ammonia decomposition product in the circulating water reaches a predetermined concentration of 5000 mg/L or more.

A device and method for forming fibrin foam, preferably utilizing a single container, comprising a base structured to be rotationally driven and including a separation chamber disposed and structured to receive a blood sample therein. The base includes a reaction chamber disposed in fluid communication with said separation chamber. The blood sample is separated into a plasma segment and a packed cell segment when subjected to sufficient centrifugation concurrent to the driven rotation of the base. According to structural features, and in some instances concurrent and continuous centrifugation, the plasma segment is directed from said separation chamber into said reaction chamber which includes sufficient quantities of gas and reactant composition to facilitate formation of fibrin foam therein concurrent to centrifugation. Further centrifugation of the fibrin foam and the inclusion of additional features such as a pressurized reaction chamber facilitate the formation of fibrin foam exhibiting varying chemical and/or physical properties.

A system, comprising a Trickle Bed Reactor (TBR), a microalgae cultivation module, and a feedback module is used to sustainably boost CO2 fixation for growing micro-algae. The TBR comprises a packing material in the form of non-porous particles with a high surface-to-volume ratio, forming a substrate for attachment of Volatile Fatty Acid (VFA) producing microbes, fed with CO2 (and/or CO), H2, nutrients, and a moistening liquid. The TBR output is fed to the microalgae cultivation module which uses micro-algae selected or adapted for increased productivity in the presence of VFAs. No CO2 needs to be fed to the microalgae cultivation module. At least part of the output of the microalgae cultivation module is fed by the feedback module back to the TBR either as a source of nutrients or for as a means backflushing for unclogging or expulsing the packing material from the TBR for cleaning/disinfection. The overall CO2 balance of the system operation is negative.

An apparatus for sampling a cell culture includes a sampler for connecting to a bioreactor with a fixed bed including the cell culture. A releasably attached sample portion for positioning within or adjacent the fixed bed includes a substrate on which cells may be grown and then removed from the bioreactor to provide an indication of cell growth. A kit for sampling a cell culture bed of a bioreactor includes the sampler for sampling the cell culture bed with the releasably attached sample portion, along with a container adapted to detach the sample portion from the sampler. A method of obtaining a sample of a cell culture in a bed within a bioreactor includes positioning a sampler positioned at least partially in or adjacent to the bed to promote the growth of cells on a releasably attached portion of the sampler, withdrawing the sampler from the bioreactor, and detaching the portion of the sampler.

The current invention relates to a bioreactor cabinet, configured to be incorporated in a biomolecule production system, wherein said bioreactor cabinet is preferably a mobile bioreactor cabinet suited to receive a bioreactor, said bioreactor cabinet is provided with a bioreactor docking station, wherein said bioreactor cabinet, more preferably a side wall of said bioreactor cabinet, is provided with a connector allowing the transmission of power, signals and/or data when paired with a biomolecule production system, such as a bioreactor chamber of said system. The current invention equally relates to a biomolecule production system and methods for producing biomolecules.

An apparatus for culturing cells includes a bioreactor. The bioreactor may be modular and may include in a chamber a fixed bed, such as an unstructured or structured fixed bed (such as a spiral bed) for culturing cells, with a return column arranged centrally within the chamber. The modular bioreactor may include a plurality of structured fixed bed arranged in a stacked configuration. The modular bioreactor may include an outer casing forming a space for conditioning (e.g., insulating, heating, cooling) at least a chamber in which cells are cultured. The bioreactor may also include an impeller with radially curved blades, and may also suspend the impeller so that it may move from side-to-side and align with an external drive. Related methods are also disclosed.

The present invention relates to a solid state fermentation process for producing hydrogen, and to a bioreactor and solid support for use in the fermentation process.

We have modified a commercially-available adherent cell culture bioreactor in several ways to increase productivity of cultured cells, while decreasing contamination risk. We found that modifying a commercially-available adherent cell culture bioreactor to provide for slower cell culture medium flow unexpectedly and dramatically increases the productivity of the cultured adherent cells. We also developed a new sampling manifold configuration and new way of taking samples, to reduce contamination risk.

We have modified a commercially-available adherent cell culture bioreactor, developing a new sampling manifold configuration and new way of taking samples to reduce contamination risk.

A bioreactor for cell culture comprising, a first set of open top troughs that are interconnected by a first set off low channels to form a first cascade, a second set of open top troughs that are interconnected by a second set of flow channels to form a second cascade, and a set of interconnecting flow channels coupled between the first cascade and the second cascade, wherein the first cascade circulates a fresh media and the second cascade circulates a cell culture and a first quantity of the fresh media from first cascade is supplied to the second cascade through the set of interconnecting flow channels when a second quantity of cell culture is removed from the second cascade.