C12M27/20

BIOREACTOR DESIGN AND METHODS OF MANUFACTURE THEREOF
20210238530 · 2021-08-05 ·

Disclosed herein is a bioreactor comprising a vessel comprising; a first tube for transporting retentate to a retentate receiving tank; a second tube that surrounds the first tube for transporting a permeate to a permeate receiving tank; and a third tube that surrounds the second tube; wherein the third tube is in fluid communication with a sparger; and wherein the third tube transports a fluid that sparges a biological broth disposed in the vessel and wherein a membrane that separates the first tube from the second tube separates the biological broth into the permeate and the retentate.

System for growing and reproducing microorganisms
11046924 · 2021-06-29 · ·

A system for growing and reproducing microorganisms that includes a basin system that includes a number of basins, where each basin has a vertical meandering system which is formed by partitions and which can be illuminated, each basin is filled with a nutrient suspension, at least one outer wall of each basin is double-walled such that a cavity is formed, a temperature control medium for controlling the temperature of the nutrient suspension can flow through the cavity.

AN APPARATUS AND A METHOD FOR COMPOSTING ORGANIC MATERIAL
20210198161 · 2021-07-01 ·

An apparatus and a method for composting organic material. The apparatus comprises a container (10) having a first end (11), a second end (12) in the form of a hemispherical wall, and a jacket (13) extending between said ends. The container operates in an inclined (al) position. A transporting and mixing device (30) in the container transports organic material in a transport direction (L1) from the first to the second end and simultaneously mixes the organic material. The transporting and mixing device directs the organic material towards the hemispheric wall, whereby the organic material is first directed upwards along the hemispheric wall and then turned back against the transport direction. A fluffing device (40) in the container comprises a shaft (41) being perpendicular to the transport direction (L1) and cutter blades (50) extending outwards from the shaft (41).

Single-use cell culturing apparatus and culturing bag

A single-use cell culturing apparatus and a culturing bag are provided, each of which can improve efficiency of stirring a culture solution and further reduce a possibility of leakage of the culture solution. The single-use cell culturing apparatus of the present invention includes a housing that accommodates the culturing bag which is flexible and can seal the culture solution inside thereof. The housing has, on an inner surface thereof, a curved convex-shaped protrusion provided at a portion of a contact face at which the housing is in contact with the culturing bag. The culturing bag of the present invention is accommodated in the housing of the single-use cell culturing apparatus; is flexible; and can seal the culture solution inside thereof. The culturing bag includes a concave portion having a shape corresponding to the curved convex protrusion disposed on a part of the housing.

Bioreactors
20210155885 · 2021-05-27 ·

Disclosed are bioreactor flasks (10) including a volume extending between a first volume end and a second volume end for the cultivation of cells or other microorganisms, said volume having a horizontal cross section area (CSA) which increases in a direction from the first volume end to the second volume end. The flask optionally includes a housing including a cylindrical lower portion (14) and an inverted truncated conical upper portion (16) which provides said increasing CSA. Disclosed also are arrays of flasks (10), supported in a tray for collective agitation.

Methods and systems for efficient bioreactor mixing and light utilization embodying low process energy and scalability
11028355 · 2021-06-08 · ·

Embodiments of the present invention may provide fluid flow coordinators, passive flow field modifiers, or even inwardly protruding helical spines which can be used in continuous, scalable, low energy usage, bioreactor systems perhaps to provide optimal mixing of microorganisms with nutrients, gases, or the like or even to move microorganisms, such as algae, in and out of light for effective and optimal growth.

Algae scrubber with directed water flow
11008239 · 2021-05-18 · ·

A water filtering system is provided for growing algae that filters the water. The system may include a container having a cylindrical inner surface and an opening at one end of the container. A clear central core including a cavity may be disposed inside the container and a light source may be disposed inside the cavity of the clear central core. A screen mesh may be disposed inside the container such that a surface of the screen mesh is parallel to the cylindrical inner surface of the container. The system may include an inlet configured to route water into the container and an outlet configured to route water from the container. A lid may cover the opening of the container.

BIOREACTOR AND RELATED METHODS

An apparatus for culturing cells includes a bio reactor. The bioreactor may be modular and may include in a chamber a fixed bed, such as an unstructured or structured fixed bed (such as a spiral bed) for culturing cells, with a return column arranged centrally within the chamber. The modular bioreactor may include a plurality of structured fixed beds arranged in a stacked configuration. The modular bioreactor may include an outer casing forming a space for conditioning (e.g., insulating, heating, cooling) at least a chamber in which cells are cultured. The bioreactor may also include an impeller with radially curved blades, and may also suspend the impeller so that it may move from side-to-side and align with an external drive. Related methods are also disclosed.

PHOTOBIOREACTOR SYSTEMS AND METHODS
20230407218 · 2023-12-21 · ·

A photobioreactor including a containment structure containing a liquid culture medium for cultivating seaweed. The containment structure includes a sidewall extending vertically between a top and bottom section where the bottom section has an effluent arranged to allow extraction of cultivated seaweed. A spiral liner is positioned adjacent to an inside surface of the sidewall. Light emitters are arranged along a surface of the spiral liner. Flow generators, positioned within the containment structure in a spiral configuration between the top section and bottom section, are configured to direct a flow of the liquid culture medium from the top section toward the bottom section of the containment structure.

Single Use Container Including a Collapsible Baffle Having Channels
20210054327 · 2021-02-25 ·

A collapsible container for a fluid that includes a flexible material, defining an internal working volume; at least one collapsible baffle adhered within the working volume of said collapsible container, the at least one baffle having one or more channels for delivering one or more fluids into the working volume via at least one hole in said one or more channels, one or more channels in said container for exiting or venting fluids from the working volume, and an impeller assembly disposed at least partially within said working volume of said container.