A bioreactor is disclosed. The bioreactor comprises at least one rise chamber containing a growth medium and at least one fall chamber connected to the at least one rise chamber at a top and at a bottom to form a loop. A first gas inlet is connected to the at least one rise chamber for supplying a gas flow to the at least one rise chamber and a second gas inlet supplied gas enriched with carbon dioxide.

The present invention relates to the field of fermentation. In particular, the present invention relates to a method and apparatus for production of products by use of living cells or active components derived from such cells using a bioreactor having a built in gas distributor and a specific system/device for handling foam formed in the process. The invention also relates to a bioreactor comprising: a reaction chamber having a fermentation zone and a foam settling zone, wherein the reaction chamber is arranged such that the foam settling zone is spaced from or physically separated from the fermentation zone so as to reduce the effect of activity in the fermentation zone on foam in the settling zone. The separation of the fermentation zone from the activity of the fermentation zone encourages settling of the foam. The invention also provides a method of forming a bioreactor comprising: overlapping two flat, flexible sheets of material; and causing said two sheets to adhere to each other in selected areas so as to define a reaction chamber. This is a particularly cost-effective way to produce a single use, disposable reactor.

A reactor system is provided for improved fermentation of a gaseous substrate through the introduction of a secondary loop to a forced-circulation loop reactor. The reactor comprises a primary loop through which fermentation broth comprising a gaseous substrate is circulated through a riser segment and a downcomer section by a loop pump. Downstream of the loop pump a portion of fermentation broth is withdrawn from the downcomer section and is directed to the top of the reactor via a secondary loop. Further provided is a method for improving the mass transfer of a gaseous substrate to a fermentation broth in a fermentation vessel comprising a secondary loop. Further provided is a method for reducing foam in the headspace of a fermentation vessel comprising a secondary loop.

An algae production reactor system according to the invention comprises a reactor vessel which is provided with:one or more liquid inlets and one or more liquid outlets;one or more gas inlets at the bottom, said gas inlets being connected with a source of carbon dioxide, and one or more gas outlets at the top of the vessel;vertically interspaced and joined pairs of double glass plates which are at least partially submerged in the reactor liquid, said double glass plates having a layer of light-scattering particles in between and having a flat side being exposed to a light source; andmeans for vertically circulating reactor liquid.

A photo-bioreactor and method of operating are described. The photo-bioreactor includes a reactor vessel arranged to contain a fluid medium within which bio-material is grown, and at least one light-emitting rod extending into the reactor vessel, wherein the light-emitting rod has an elongate tubular member characterized by a length along a longitudinal axis and a width along an axis normal to the longitudinal axis, and designed with an outer wall that encloses one or more light-emitting devices arranged along the longitudinal axis, the outer wall being transparent to at least part of the light emitted by the one or more light-emitting devices into the reactor vessel. The photo-bioreactor further includes a drive system coupled to the elongate tubular member, and operatively configured to rotate the light-emitting rod about the longitudinal axis within reactor vessel, and circulate the fluid medium through the reactor.

The invention proposes a high-pressure environment biological enrichment and spray-type solid isolation and cultivation device, including a spray-type isolation and cultivation solid unit, and a biological enrichment unit. In the case of constructing a high-pressure, low-temperature environment consistent with the marine environment, the biological enrichment unit is used to realize enrichment and multi-stage purification process of marine microorganisms, obtain a biological enrichment fluid and inject the biological enrichment fluid into the spray-type isolation and cultivation solid unit; and the spray-type isolation and cultivation solid unit is use to convert the biological enrichment fluid into a state of microbeads, so that the biological enrichment fluid can be isolated and cultivated in a dispersed state.

An exposure device for exposing microorganisms to gaseous pollutants and a corresponding in-situ multi-toxicity endpoint detection system are provided. The detection system based on the exposure device disclosed in the present application may perform controlled accumulation of pollutants in air, and implements in-situ, comprehensive, quick, and low-cost assessment of toxicity effects of pollutants in air of a target site. The exposure device and the detection system disclosed in the present application can effectively avoid toxicity distortion caused by complex collection and transfer process, complex chemical reactions in a liquid elution process in conventional toxicity detection methods for gaseous pollutants.

An algae production reactor system comprising a reactor vessel which is disclosed. The system comprises (a) one or more liquid inlets and one or more liquid outlets; (b) one or more gas inlets at the bottom, the gas inlets being connected with a source of carbon dioxide, and one or more gas outlets at the top of the vessel; and (c) vertically interspaced and joined pairs of double glass plates which are at least partially submerged in the reactor liquid, the double glass plates having a layer of light-scattering particles in between and having a flat side being exposed to a light source, wherein part of the spaces between the double glass plates is arranged above the gas inlets for vertically circulating reactor liquid.

Disclosed is a system for cultivating and harvesting a cyanobacterial biomass. The system comprises at least one vessel that, when in operation, grows the cyanobacterial biomass in a nutrient growth media under regulated growth conditions and a base unit configured to receive the at least one vessel. The system also comprises at least one light source and a cultivation air pump that, when in operation, supplies light, heat and air to the at least one vessel. Notably, the cultivation air pump supplied air via a one-way air valve in the at least one vessel. The system also comprises at least one photodiode that, when in operation, measure a cyanobacterial biomass concentration in the at least one vessel. Disclosed also is a method for cultivating and harvesting a cyanobacterial biomass.

A portable bioreactor is provided. The portable bioreactor may comprise: a frame unit; a cell culture unit which has one side mounted to the frame unit and in which a plurality of supports for cell culture are arranged, the cell culture unit being provided with an inlet, through which a medium supplied from the outside flows in, and an outlet, through which the medium inside the cell culture unit is discharged to the outside, a medium adjustment unit installed in the frame unit and storing therein a certain amount of medium for the cell culture; a circulation pump installed and fixed to the frame unit to circulate the medium stored in the medium adjustment unit; and a gas supply unit for supplying gas to the medium adjustment unit to maintain the medium stored in the medium adjustment unit at a constant pH.