A liquid is efficiently suctioned and discharged from and to a container formed by a plurality of aligned storing portions for storing the liquid, using a plurality of nozzles. Provided is a liquid suction/discharge device including a container support device for supporting a culture container formed by a plurality of aligned storing portions, and a nozzle support device for supporting a plurality of nozzles in a state in which distal ends of the nozzles are directed downward. The nozzle support device includes a nozzle support member that swingably supports the plurality of nozzles using prescribed parts as support points, and the liquid suction/discharge device further includes a nozzle inclination device for causing each of the nozzles to be inclined with respect to the nozzle support member.

A manipulation apparatus and a manipulation method for performing culturing, manipulation, and analysis of minute samples such as cells and microbes on a large scale, the manipulation apparatus including a stage unit on which a predetermined cell incubator is mounted and a probe array unit having a plurality of probes. The probe array unit includes a first probe array and a second probe array. The first probe array includes a plurality of probes arranged side by side at a predetermined pitch along the X-axis direction. The second probe array includes a plurality of probes arranged side by side at a predetermined pitch along the Y-axis direction.

An image capturing system includes a camera unit that captures an image of a cell; a display unit; an input unit that receives input from an operator regarding a selection operation on the cell; an analyzing unit that analyzes the image corresponding to the cell to which the selection operation is given and extracts a feature amount of the cell; and a specifying unit that specifies a recommended cell. The specifying unit sets a parameter that defines a range of the cell to be selected based on the feature amount of the cell to which the selection operation is given up to a first time point. In an image including the cell obtained by image capturing at a second time point later than the first time point, the specifying unit specifies the recommended cell on which the operator is prompted to make a selection based on the parameter.

A system and method for printing cells in a medium. A multi-dimensional printer, stably constructed of low-mass parts, can include a computer numerically controlled system that can enable motors driving delivery systems. The motors can include encoders that can enable achieving arbitrary resolution. The motors can drive ballscrews to enable linear motion of delivery systems, and the delivery systems can enable printing of a biological material in a pre-selected pattern in a petri dish. The petri dish can accommodate a medium such as a gel, and can further accommodate a vision system that can detect actual position and deflection of the delivery system needle. The printer can accommodate multiple delivery systems and therefore multiple needles of various sizes.

A cell picking device that sucks cells from a liquid sample in a sample container and accommodates the sucked cells in any of a plurality of wells of an accommodating plate, includes a suction discharger that sucks cells in the sample container and discharges the sucked cells into any of the plurality of wells, the receiver that receives selection of a well in which cells are to be accommodated out of the plurality of wells of the accommodating plate as a selection well, a driver that adjusts a relative positional relationship between the suction discharger and the plurality of wells of the accommodating plate, and a work controller that controls the driver such that the suction discharger discharges cells into the received selection well out of the plurality of wells of the accommodating plate.

A sampling system includes a graduated sampling chamber configured for fluid connection to a sample source, a pump device configured for fluid connection with the sampling chamber, and a sterile air filter intermediate the pump device and the sampling chamber, wherein the pump device is selectively actuatable to draw a volume of fluid from the sample source into the sampling chamber.

An analytical instrument having a sensing system, a stage adapted to receive a sample carrier, a motion actuator assembly for positioning the sensing system and/or the stage, a temperature control element, and a signal processing module are disclosed. Methods of analyzing cell samples with the analytical instrument are also disclosed.

A cell transplantation device for placing a cell group at a target region in at least one of an intradermal layer and a subcutaneous layer in a living body, including a device body including a protruding portion having an accommodating portion for accommodating a liquid composition including the cell group. The protruding portion has an opening that communicates with the accommodating portion, and the protruding portion penetrates a skin surface of the living body such that the opening of the protruding portion reaches the at least one of the intradermal layer and the subcutaneous layer and that the cell group accommodated in the accommodating portion is placed at the target region through the opening.

A cell and medicament dispensing device for drug screening is configured to dispense minute amount of cells and medicaments. The device has a base, a transfer plate serving mechanism, a transfer plate positioning mechanism, an injection mechanism, a cell culture plate positioning mechanism, and a dispensing mechanism. The transfer plate serving mechanism moves a transfer plate to the transfer plate positioning mechanism. The injection mechanism injects cells and medicaments into recesses in the transfer plate. A cell culture plate is fixed in the cell culture plate positioning mechanism. The dispensing mechanism moves back and forth between a position above the transfer plate and a position above the cell culture plate to dispense the cells or medicaments from the transfer plate to the cell culture plate. As a result, the process of drug screening is automated to reduce labor and improve quality significantly.

A cell and medicament dispensing device for drug screening is configured to dispense minute amount of cells and medicaments. The device has a base, a transfer plate serving mechanism, a transfer plate positioning mechanism, an injection mechanism, a cell culture plate positioning mechanism, and a dispensing mechanism. The transfer plate serving mechanism moves a transfer plate to the transfer plate positioning mechanism. The injection mechanism injects cells and medicaments into recesses in the transfer plate. A cell culture plate is fixed in the cell culture plate positioning mechanism. The dispensing mechanism moves back and forth between a position above the transfer plate and a position above the cell culture plate to dispense the cells or medicaments from the transfer plate to the cell culture plate. As a result, the process of drug screening is automated to reduce labor and improve quality significantly.