C12M41/14

Cell culture apparatus and cell culture method
11180726 · 2021-11-23 · ·

Provided is a cell culture apparatus including a cell supply unit that supplies cells; a culture medium supply unit that supplies a culture medium; an additive supply unit that supplies an additive for inducing the differentiation of undifferentiated cells; a stirring unit that stirs a processing target; a separation unit that separates a component contained in the processing target; a culture vessel that cultures the cells; a first flow channel that forms a circulation route passing through the cell supply unit, the stirring unit, the separation unit, and the culture vessel; a second flow channel that connects the culture medium supply unit and the first flow channel; a third flow channel that connects the additive supply unit and the first flow channel; and a control unit that controls the feeding of liquid through the first flow channel, the second flow channel, and the third flow channel.

Modular incubator system

An incubator (110, 140) for the reception of an individual sample carrier, a shelving system (100) for such incubators, a transport container for such incubators, as well as a modular system are suggested, wherein the incubators can be inserted and withdrawn (130) independently of one another, can be supplied with electricity, water and a gas via corresponding connections (150), and can communicate with a computer network via a wireless connection. Such a system reduces the risk of contamination or confusion in the lab and avoids interruptions in the monitoring and controlling of the environmental conditions in the respective incubators. These can rather independently maintain the most favourable environmental conditions for the respective samples, both during storage and also during a transport operation. The insertion and withdrawal of individual incubators from the shelving system does not, or only very briefly, interrupt the monitoring and control of the conditions in the interior of the incubators.

DEVICE FOR INCUBATING CULTURES, METHOD FOR INCUBATING CULTURES AND USE
20210348111 · 2021-11-11 · ·

The invention relates to a device for incubating cultures, comprising a culture chamber storing the cultures, the cultures being fumigated with an incubation gas. The invention is characterized in that the incubation gas source is used when incubating the cultures with the incubation gas source which is free of liquid incubation gas.

DEVICES FOR INCUBATING AND WASHING BIOLOGICAL SAMPLES AND METHODS USING THEREOF
20210348099 · 2021-11-11 ·

The present disclosure provides devices, machines and methods for incubating or washing a biological sample. This disclosure provides a device comprising a motor and a control for the motor, a supporting frame comprising a receptacle, an assembly comprising a rotatable liquid storage container, a washing cassette, and a liquid collection and recovery tank. The disclosure also provides methods using the device.

AUTOMATED GAS CONTROL HYPOXIC CHAMBER FOR MONITORING OXYGEN CONCENTRATION

A hypoxic chamber system comprises a hypoxic chamber having: a housing, an internal receiving chamber formed within the housing, a lid operably connectable to the housing to seal the receiving chamber in a closed position, a first input and a second input in communication with the receiving chamber, and an oxygen sensor positioned in the receiving chamber; a first regulator valve operatively connected to the first input and an oxygen source; a second regulator valve operatively connected to the second input and a non-oxygen source; and a controller electrically connected to the first regulator valve, the second regulator valve, and the oxygen sensor.

CELL CULTURE SHEET ASSEMBLY FOR LARGE-CAPACITY INCUBATOR, AND LARGE-CAPACITY INCUBATOR COMPRISING SAME

Provided is a cell culture sheet for a large-capacity incubator. A cell culture sheet according to one embodiment of the present invention is a cell culture sheet provided in a large-capacity incubator having a plurality of sheets disposed to be spaced apart at predetermined intervals therein, wherein the cell culture sheet has an area of 100 cm.sup.2 or more and a bending depth of 0.5 cm or less. As such, even when the culture sheets are closely placed in a limited volume of space, there is little sagging or shape deformation in a specific direction to prevent the occurrence of contact with adjacent culture sheets, thereby preventing a decrease in cell culture volume due to a dead space. Furthermore, since the flow of a cell culture fluid due to the occurrence of contact can be minimized or prevented, a large capacity of cells can be stably and smoothly cultivated such that the cell culture sheet is very suitable for a large-capacity incubator and can be widely applied to the cell culture industry.

LARGE-SCALE CELL CULTURE SYSTEM

A large-scale cell culture system is provided. The large-scale cell culture system according to one embodiment of the present invention includes: an incubator that includes an inner space to provides a culture environment in which a cell is stably cultured; a cell culture part that is disposed in the inner space and includes multiple supporters for cell culture disposed therein; a medium supply part that is disposed in the inner space and stores a predetermined amount of medium supplied to the cell culture part; and a pump that is disposed in the inner space, and is connected to the cell culture part and the medium supply part through a connection pipe, respectively, and circulates the medium so that the medium stored in the medium supply part is recovered to the medium supply part after being supplied to the cell culture part, the multiple supporters being provided in a plate shape having a predetermined area, and arranged in a state separated apart from each other at a predetermined distance along a height direction inside the cell culture part.

Gas Collection Device
20220002647 · 2022-01-06 · ·

The gas collection device includes a constant temperature chamber whose interior is maintained at a set temperature; a culture flask unit located inside the constant temperature chamber and culturing bacteria therein; a mass flow controller located outside the constant temperature chamber and connected to the culture flask unit through an injection flow path to control a gas injected into the culture flask unit through the injection flow path; and an impinger located outside the constant temperature chamber and connected to the culture flask unit through a discharge flow path to receive a gas discharged from the culture flask unit through the discharge flow path in real time.

Cell maintainer for autologous cell therapy production
11168297 · 2021-11-09 · ·

In some aspects, the invention relates to automated cell culture incubators and their methods of use. In one aspect, the disclosure provides cell culture incubators having an airlock chamber, a storage chamber and/or an internal chamber. In some aspects, the disclosure provides methods for producing autologous mammalian cell cultures.

Gas Collection Device

The present invention relates to a gas collection device and is directed to a gas collection device for collecting a gas which is generated while microorganisms are cultured in a super absorbent polymer product. The gas collection device may comprise a constant temperature chamber having an interior that is configured to be maintained at a set temperature; a culture flask unit located inside the constant temperature chamber and configured to culture a bacteria therein; an adsorption unit located outside the constant temperature chamber and configured to receive a gas inside the culture flask unit; a pump unit connected to a rear end of the adsorption unit and configured to suck the gas inside the culture flask unit into the adsorption unit; and a mass flow controller located outside the constant temperature chamber and configured to control a flow rate of the gas sucked into the adsorption unit.