C12M41/18

Automated cell processing instruments comprising reagent cartridges

The present disclosure provides a reagent cartridge configured for use in an automated multi-module cell processing environment.

METHOD FOR ENHANCING THE INCUBATION OF SAMPLES, SPECIMENS AND REAGENTS USING LASERS
20190242890 · 2019-08-08 ·

A method for incubating reagents, suspensions and/or biological products to a predetermined temperature for biological testing; the method comprising the steps of: a) providing a selected biological product in a receptacle and which is required to be incubated to a temperature which simulates a natural thermal environment of the biological product; b) applying controlled heating to or near the biological product using at least one laser emitting from a laser source for a time sufficient to reach a target temperature or which simulates a target temperature of the natural thermal environment in which the biological product exists.

MOVABLE CELL INCUBATOR
20190211295 · 2019-07-11 ·

A movable cell incubator contains: a body, a first lid, a second lid and an electric control unit. The body includes a first internal space, a refrigeration room, and an airtight culture room. The first lid airtightly covers the culture room, the second lid airtightly covers the refrigeration room, and the control unit includes a microprocessor, a power module, a digital/analog conversion module defined between a microprocessor and the power module, a heating module controlling temperature of the culture room, a cooling module supplying cold source to the refrigeration room, a peristaltic pump module, a flow sensing module, a CO2 detective supply module supplying CO2 to the culture room, and a setting display module exposing and fixed on the first lid, with the peristaltic pump module aseptically connected between cell culture media and cell culture bag by multiple conveying tubes.

IN VITRO EXPOSURE SYSTEM

Disclosed is an in vitro exposure system that may radiate a uniform field having a constant wavefront to an experimental cell container and expose each cell container to a same electromagnetic field.

SYSTEM FOR AUTOMATED PREPARATION OF A REGENERATIVE EPIDERMAL SUSPENSION AND RELATED METHODS OF USE

One or more systems for automated preparation of a regenerative epidermal suspension comprises a base unit, a cartridge assembly containing a cup, and a tissue disaggregator. The system may also include related tools. The system executes one or more sequences wherein a first motor actuates the pestle against a tissue sample that is disposed along a screen within the cup while the tissue sample is in contact with, in sequence, an enzyme solution, a first buffer solution, and then a second buffer solution. To transition between fluidic contact stages or steps, the tissue disaggregator engages with and lifts the cup into a raised position within a processing area of the cartridge while a base plate motor rotates the appropriate well into alignment under the cup for each processing step. Once the sequence is complete, a user may draw up a regenerative epidermal suspension through an opening in the cartridge top cover.

MICROFLUIDIC CONTROL
20240200006 · 2024-06-20 ·

The present invention is related to the field of fluidic devices, and in particular, microfluidic cell culture systems. The present invention provides pumping, recirculation and sampling for a microfluidic device or devices. The present invention provides solutions to the control of microfluidics for both terrestrial and space applications, including the control over the movement of fluids in zero gravity or microgravity.

Heat exchanger system with flexible bag

A bag assembly for use with a heat exchanger includes a flexible bag having of one or more sheets of polymeric material, the bag having a first end that bounds a first compartment and an opposing second end that bounds a second compartment, a support structure being disposed between the first compartment and the second compartment so that the first compartment is separated and isolated from the second compartment. A first inlet port, a first outlet port, and a first drain port are coupled with the flexible bag so as to communicate with the first compartment. A second inlet port, a second outlet port, and a second drain port are coupled with the flexible bag so as to communicate with the second compartment.

Microfluidic control
11999932 · 2024-06-04 · ·

The present invention is related to the field of fluidic devices, and in particular, microfluidic cell culture systems. The present invention provides pumping, recirculation and sampling for a microfluidic device or devices. The present invention provides solutions to the control of microfluidics for both terrestrial and space applications, including the control over the movement of fluids in zero gravity or microgravity.

METHODS AND SYSTEMS FOR DRUG DISCOVERY AND SUSCEPTIBILITY ASSAY IN USING A FERROFLUID
20190120822 · 2019-04-25 ·

A system for determining drug effectiveness on a plurality of cells is described. The system includes flowing a ferrofluid mixed with a plurality of biological cells through an inlet portion of a cartridge, the cartridge comprising a plurality of microfluidic channels, the inlet is in communication with a portion of each of the plurality of channels, applying a magnetic field proximate at least one of the inlet portion and the plurality of micro-channels, wherein the magnetic field is configured to apply an indirect force on the mix, separating biologic cells according to at least a first type as the mix flows in a first direction; and directing at least the first type of cells toward a first sensor functionalized with receptors via at least one of the micro-channels, the sensor arranged proximate to a second portion of at least one of the micro-channels downstream from the first inlet portion.

APPARATUS FOR ACCELERATING REPRODUCTION OF ODOR FROM AIR-CONDITIONER AND METHOD FOR THE SAME
20190119625 · 2019-04-25 ·

The present invention relates to an apparatus and a method that can accelerate reproduction of odor from an air-conditioner by segmenting microorganisms, a temperature/humidity condition and nutrients for metabolism of the microorganisms as conditions for reproducing the odor from the air-conditioner and setting the segmented microorganisms, a temperature/humidity condition and nutrients for metabolism of the microorganisms according to an accelerated condition thereof.