The present invention relates to an active ingredient comprising oligo-glucans, obtained from the cytosolic fraction of a yeast of the species Saccharomyces cerevisiae, a cosmetic composition comprising said active ingredient and cosmetic uses thereof, in particular to improve the regeneration of the skin and combat aging thereof.

Metal bioremediation and metal mining strategies can include compositions and methods.

Method for digesting yeast, in particular brewer's yeast, for the isolation of proteins and saccharides comprising the steps: a) Providing a yeast suspension, in particular a brewer's yeast suspension; b) Physical digestion of the yeast in the yeast suspension; c) Microfiltration of the digested yeast suspension from step b); d) Ultrafiltration of the permeate of the microfiltration from step c) wherein a phase with proteins as the main solid component is separated as the retentate of the ultrafiltration; e) Treating the retentate of the microfiltration from step c) with a protease under basic conditions and subsequently separating a phase with mannan as the main solid component, in particular by filtration and/or centrifugation; f) treating the phase retained in step e) successively first at basic and then at acidic conditions and subsequently separating a phase with glucan as the main solid component, in particular by filtration and/or centrifugation.

Disclosed are immunogenic pharmaceutical compositions comprising yeast lysates for inducing cellular immune responses, methods of making immunogenic compositions comprising yeast lysates, methods of treatment comprising administration of said compositions, and kits comprising said yeast lysate compositions. Disclosed immunogenic compositions further comprise an antigen heterologous to the yeast, and may comprise whole yeast and immunostimulatory agents. Induced cellular immune responses comprise cytotoxic T cell activation with specificity to the antigen comprising the immunogenic composition. Various methods of formulation and administration to a patient are described herein, especially wherein the patient suffers from an infectious disease and/or cancer.

The present invention addresses the problem of preparing an intracellular enzyme of yeast by a simple method. A pulsed electric field is applied to yeast, and the enzyme extracted into an extracellular solution is recovered.

Provided are a high immune yeast cell wall, and a preparation method therefor and the use thereof. For the high immune yeast cell wall, the dissolution rate is 40%, glucan with a relative molecular weight of 80-200 kDa accounts for more than 99% of the total mass of glucan, and the content of glucan is 20%-40% on the basis that the mass of the high immune yeast cell wall is 100%. The high immune yeast cell wall has an improved dissolution rate and immune efficacy, is derived from a yeast, and can be used as a raw material or additive of feed.

The present invention relates to the use of a yeast extract including at least 10 wt % of nucleic acids, preferably at least 15 wt %, and more preferably 30 to 95 wt %, relative to the total weight of said extract, said nucleic acids being formed from fragments of ribonucleic acid (RNA), for clarifying musts and liquids, in particular wines and teas.

Disclosed are immunogenic pharmaceutical compositions comprising yeast lysates for inducing cellular immune responses, methods of making immunogenic compositions comprising yeast lysates, methods of treatment comprising administration of said compositions, and kits comprising said yeast lysate compositions. Disclosed immunogenic compositions further comprise an antigen heterologous to the yeast, and may comprise whole yeast and immunostimulatory agents. Induced cellular immune responses comprise cytotoxic T cell activation with specificity to the antigen comprising the immunogenic composition. Various methods of formulation and administration to a patient are described herein, especially wherein the patient suffers from an infectious disease and/or cancer.

The present invention is related to a novel process on biological production of lipophilic substances in an oleaginous host cell, particularly Yarrowia lipolytica, comprising modification in the N-glycosylation pathway, leading to higher yield and product purity with further facilitating the overall production process.

The present application provides a preparation method for a yeast extract, a corresponding product thereof and an application thereof in soft drinks. The preparation method for a yeast extract of the present application is an autolysis method assisted by adding papain. A chelating agent and an emulsifying agent are added in an autolysis process to adjust sweetness, umami and saltiness of a yeast extract, so as to make the yeast extract more suitable for soft drinks.