C12R2001/15

Preparation of (R)-3-hydroxybutyric acid or its salts by one-step fermentation
11198890 · 2021-12-14 · ·

The subject invention relates to a process of preparing (R)-3-hydroxybutyric acid or a salt thereof by one-step fermentation with a nonpathogenic microorganism. The fermentation of (R)-3-hydroxybutyric acid was performed by supplying with certain carbon and nitrogen sources. These microorganisms include a Glutamic acid Bacterium HR057 strain or one type of genetically engineered Corynebacterium Glutamicum.

Method for the fermentative production of L-lysine using an L-lysine excreting bacterium of the species <i>Corynebacterium glutamicum </i>having a completely or partly deleted WHIB4 gene

Fermentative production of L-lysine using an L-lysine excreting bacterium of the species Corynebacterium glutamicum having a completely or partly deleted whiB4 gene is provided.

MICROORGANISM WITH ENHANCED L-HISTIDINE PRODUCTION CAPACITY AND METHOD FOR PRODUCING HISTIDINE BY USING SAME
20220205003 · 2022-06-30 · ·

Provided are a microorganism having an enhanced L-histidine producing ability and a method of producing histidine using the same.

RECOMBINANT MICROORGANISM INTRODUCED WITH GLUTARIC ACID TRANSPORTER GENE AND METHOD OF PREPARING GLUTARIC ACID USING SAME
20220205000 · 2022-06-30 ·

The present invention relates to a recombinant microorganism imparted with increased ability to produce glutaric acid by further introducing a gene encoding a polypeptide having glutaric acid transporter activity into a microorganism having ability to produce glutaric acid, and to a method of preparing glutaric acid using the recombinant microorganism. According to the present invention, glutaric acid used for the preparation of various compounds such as polyamide, polyurethane, 1,5-pentanediol, and 5-hydroxyvaleric acid can be biosynthesized at high yield.

METHOD OF TREATING BOVINE MASTITIS

A method of treating or preventing mastitis in a bovine animal comprising administering to the animal a therapeutically effective amount of particular microbes thereby treating or preventing mastitis in the animal.

GENETICALLY MODIFIED MICROORGANISM AND METHOD FOR PRODUCING TARGET SUBSTANCE USING SAME
20220177924 · 2022-06-09 · ·

The present disclosure relates to a genetically modified microorganism satisfying some of predetermined conditions. The predetermined conditions include: (I) succinate dehydrogenase activity or fumarate reductase activity being reduced or inactivated relative to a wild-type microorganism; (II) lactate dehydrogenase activity being reduced or inactivated relative to the wild-type microorganism; (III) the genetically modified microorganism having modified phosphoenolpyruvate carboxylase activity showing resistance to feedback inhibition by aspartic acid in wild-type phosphoenolpyruvate carboxylase activity, or exogenous phosphoenolpyruvate carboxylase activity having higher resistance to feedback inhibition by aspartic acid than that of the wild-type phosphoenolpyruvate carboxylase activity shown by the wild-type microorganism; and (IV) pyruvate:quinone oxidoreductase being reduced or inactivated relative to the wild-type microorganism.

Compositions and related methods for agriculture

Provided herein are agents, compositions, and methods for agricultural use, e.g., for altering the level, activity, or metabolism of one or more microorganisms resident in a host nematode or arthropod (e.g., honeybee or silkworm), the alteration resulting in an increase in the fitness of the host. The invention features a composition that includes an agent (e.g., phage, peptide, small molecule, antibiotic, or combinations thereof) that can alter the host's microbiota in a manner that is beneficial to the host. By promoting favorable microbial levels, microbial activity, microbial metabolism, and/or microbial diversity, the agents described herein may be used to increase the fitness of a variety of beneficial nematodes or arthropods, such as bees and silkworms, utilized in agriculture and commerce.

Microorganism of genus <i>Corynebacterium </i>producing L-arginine and method for producing L-arginine using the same

A microorganism of the genus Corynebacterium producing L-arginine, and a method for producing L-arginine using the same.

Preparation of (R)-3-Hydroxybutyric Acid or Its Salts by One-Step Fermentation
20220162653 · 2022-05-26 · ·

The subject invention relates to a genetically modified microorganism comprising a (R)-3-hydroxybutyric acid pathway and being able of producing (R)-3-hydroxybutyric acid, and a method of preparing (R)-3-hydroxybutyric acid or a salt thereof using the genetically modified microorganism.