Patent classifications
C
CHEMISTRY; METALLURGY
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C12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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C12Y
ENZYMES
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101/00
Oxidoreductases acting on the CH-OH group of donors (1.1)
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C12Y101/01
with NAD+ or NADP+ as acceptor (1.1.1)
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C12Y101/01247
Codeinone reductase (NADPH) (1.1.1.247)
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C12Y101/01247

METHODS OF PRODUCING EPIMERASES AND BENZYLISOQUINOLINE ALKALOIDS
20180163241 · 2018-06-14 ·

A method of epimerizing an (S)-1-benzylisoquinoline alkaloid to an (R)-1-benzylisoquinoline alkaloid is provided. The method comprises contacting the (S)-1-benzylisoquinoline alkaloid with at least one enzyme. Contacting the (S)-1-benzyl-isoquinoline alkaloid with the at least one enzyme converts the (S)-1-benzylisoquinoline alkaloid to an (R)-1-benzylisoquinoline alkaloid.

Methods of producing epimerases and benzylisoquinoline alkaloids
12497638 · 2025-12-16 · ·

A method of epimerizing an (S)-1-benzylisoquinoline alkaloid to an (R)-1-benzylisoquinoline alkaloid is provided. The method comprises contacting the (S)-1-benzylisoquinoline alkaloid with at least one enzyme. Contacting the (S)-1-benzylisoquinoline alkaloid with the at least one enzyme converts the (S)-1-benzylisoquinoline alkaloid to an (R)-1-benzylisoquinoline alkaloid.