Patent classifications
C12Y111/01006
Preparation of Stabilized Catalase Enzymes with a Surfactant
There is provided a method of producing a stabilized microcrystalline cellulose powder containing catalase enzyme. In the method, cellulose is thoroughly mixed with phosphate borate and catalase, rinsed with water and a surfactant added. The stabilized powder may be mixed with various skin solutions (lotions, ointments and the like). The catalase enzyme can catalyze the reaction of peroxide to oxygen.
ENGINEERED ADENYLATE KINASE VARIANTS
The present disclosure provides engineered adenylate kinases, and recombinant polynucleotides encoding the engineered adenylate kinases. The present disclosure further provides uses of the engineered adenylate kinases for converting NMP to NDP.
LYMPHATIC DELIVERY OF NANOPARTICLES TO TREAT NEURODEGENERATIVE, NEUROLOGICAL, AND EYE CONDITIONS
Provided herein are composition, systems, kits, and methods for preventing and/or treating, reversing, and/or inhibiting progression of, a neurodegenerative and/or neurological conditions and/or eye conditions (e.g., retinitis pigmentosa) by administering a plurality of nanoparticles to a subject via subcutaneous, intramuscular, or intraperitoneal injection such that the plurality of nanoparticles are taken up by lymphatic capillaries and are transported to neurological and/or eye tissue of the subject via the subject's lymphatic system, wherein the plurality of nanoparticles encapsulate, or are attached or absorbed to, at least one drug agent.
METHOD FOR PREPARING CULTURES OF LACTIC ACID BACTERIA, PRODUCTS AND CULTURE MEDIA THEREFORE
- Hans BISGAARD-FRANTZEN ,
- Lars CHRISTENSEN ,
- Surender Kumar DHAYAL ,
- Francesco Cristino Falco ,
- Neda FARGHIPARAPARI ,
- Anisha GOEL ,
- Marie Penderup JENSEN ,
- Jakub KOVACS ,
- Hamed Nasri LARI ,
- Henrik Moellgaard ,
- Robin Toponen ORTHAGEN ,
- Milica RANDELOVIC ,
- Catarina SEITA ,
- Kim Ib Soerensen ,
- Tina Malling THORSEN ,
- Miguel TOSCANO ,
- Jakob WORM
The present invention relates to microbial starter cultures. More specifically, a method for preparing a microbial culture such as a lactic acid bacteria (LAB) starter culture wherein at least one microbial strain such as a lactic acid bacteria and at least one hemoprotein is inoculated in a culture medium.
Biosynthesis Of Apocarotenoids By Controlling Oxidative Stress
The present invention relates to host cells comprising genes of the mevalonate, lycopene and -ionone pathways and the hydroperoxide reductase or catalase genes. The present invention also relates to methods of producing apocarotenoids as well as kits for producing apocarotenoids comprising the host cells.
COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING DISEASES ASSOCIATED WITH OXIDATIVE STRESS
Methods and compositions for treating various indications by lessening oxidative stress in a patient are provided. A pharmaceutical composition comprises between about 0.001% to about 10.0%, or more specifically between about 0.015% to about 5%, sodium iodide or catalase by weight. The iodine ion or the catalase dissociates hydrogen peroxide into water and molecular oxygen to interrupt biological events that result in negative side effects. The pharmaceutical composition further comprises in some cases a reducing agent or various carrier materials. The pharmaceutical composition is in some cases formulated for a variety of delivery methods.
Selenium-containing nano HOF, antioxidant nanozyme, preparation method and application thereof
A multi-enzyme cascade antioxidant nano HOF and preparation method and application thereof are provided. The present invention discloses a nano HOF based on selenium-containing ligand for the first time, the nano HOF does not contain metal and has good biocompatibility, which is a universal loading platform, and has high porosity, acid and alkali resistance and thermal stability, and is size-tunable, it can coat various types of enzymes at the same time, stabilize the conformation of the enzyme through the confinement effect, the high porosity can not only provide enough space for the enzyme, but also facilitate the transport of substances and the play of catalytic properties of the enzyme, 85-90% of the activity of the coated enzyme can be maintained, ROS can be effectively scavenged through the cascade catalysis between various enzymes, which provides a new idea for the construction of bio-friendly antioxidants.
Nanoparticle for the remodeling of cancer-associated fibroblasts
Described herein are systems and methods for employing a tumor targeted cerium oxide nanoparticle system, T-CeNP, for cancer therapy to hinder cancer associated fibroblast (CAF) transdifferentiation and reprogram CAFs back to normal fibroblasts to reduce tumor size and prevent metastasis.
Degradation of sporopollenin
A composition comprised of a peroxidase, a catalase, and a peroxide that, in combination, is suitable for degradation of pollen wall sporopollenin, and coatings comprising sporopollenin in a matrix that can be selectively degraded through application of a peroxidase, a catalase, and a peroxide to the sporopollenin matrix.
Dietary Supplement for Stimulating New Hair Growth and Reversing Hair Graying
A dietary supplement for stimulating new hair growth and for reversing the graying of hair comprising a blend from about 7.0%/wt. to about 15.0%/wt. of Vitamin C, optionally from about 50 units to about 500 units of catalase, with the balance being diatomaceous earth. This blend is formulated in powder form. Each daily dosage contains from about 2.0 grams to about 3.0 grams of the blend.