Patent classifications
C12Y111/01006
Methods of treating spinal cord injury
The invention is directed to a method of treating a spinal cord injury, a neurodegenerative disease or a neuronal injury in an individual in need thereof comprising administering an effective amount of superoxide dismutase (SOD) and catalase to the individual, wherein the superoxide dismutase and the catalase are encapsulated in one or more nanoparticles that release the SOD and catalase upon administration. Another aspect of the invention is directed to compositions comprising superoxide dismutase (SOD) and catalase encapsulated in one or more nanoparticles.
System, methods, and compositions for high-level production of water-soluble cannabinoids in a plant cell culture
The inventive technology relates to systems and methods for enhanced in vivo production, accumulation and modification of cannabinoids. In one embodiment, the invention may include systems and methods for enhanced in vivo biosynthesis of chemically-modified water-soluble cannabinoids in a whole plant, or a cell suspension culture system.
Synthetically functionalized living cells for targeted drug delivery
Uniform, functional polymer patches can be attached to a fraction of the surface area of living individual cells. These surface-modified cells can cross the blood-brain barrier while remaining viable after attachment of the functional patch. Functional payloads carried by the patch can include a drug. The patch can include one or more polyelectrolyte multilayers (PEMs).
REDOX ENZYMES IN ANIMAL FEED COMPOSITIONS
Novel superoxide dismutases of fungal origin are active, gastric stable and thermal stable, and effective for use in animal feed additives. The use of superoxide dismutase in animal feed improve animal growth, animal health and intestinal health of animals.
THROMBOLYTIC AND NEURO/VASCULOPROTECTIVE NANOCONJUGATES
Provided herein are compositions, systems, kits, and methods for treating a patient with a thromboembolism by administering nanoconjugates comprising nanoparticles encapsulating and/or conjugated to: i) tissue-type plasminogen activator (tPA), and ii) at least one antioxidant enzyme selected from the group consisting of: superoxide dismutase, glutathione peroxidase, glutathione reductase, and a catalase.
Method for producing sugar carboxylic acid
To provide a method for industrially producing a sugar carboxylic acid from an oxidized starch decomposition product or oxidized transfer reaction product having a degree of polymerization of 2 or more in a high yield, using a catalase formulation which quickly decomposes hydrogen peroxide produced as a by-product in the oxidation. A method for producing a sugar carboxylic acid in which an aldehyde group on a reducing end of a starch decomposition product or starch transfer reaction product having a degree of polymerization of 2 or more and having a glucose residue at the reducing end is oxidized, the method comprising a step of treating a raw material substrate containing the starch decomposition product or starch transfer reaction product in the presence of a catalase formulation with a carbohydrate oxidase agent producing hydrogen peroxide as a by-product in carbohydrate oxidation, wherein a total volume of a reaction liquid in the treatment step is 1 L or more, wherein a predetermined amount of a basic compound is added during the treatment step; and wherein a carbonate or a hydrogen carbonate is added as the basic compound in an amount by mass corresponding to 5% or more of the predetermined amount at a start of the treatment step.
Compositions, methods of treatment, and containers including compositions
Compositions for treatment of cystinosis, products for administering eye drops, and products for storing contact lenses are provided. Compositions include solutions that can contain an effective amount of cysteamine to treat cystinosis, and an oil with a lower density than the solution. Also provided is a product including a bottle for containing a solution, the bottle being substantially free of O.sub.2. Also provided is a contact lens holder for storing one or more contact lenses in a solution, the holder including barrier layers reducing the amount of O.sub.2 entering the contact lens holder.
BENZALDEHYDE PRODUCTION METHOD
A method for producing benzaldehyde is provided. Benzaldehyde is produced by a method including a step of using amino acid deaminase (AAD), 4-hydroxymandelate synthase (HMAS), (S)-mandelate dehydrogenase (SMDH), and benzoylformate decarboxylase (BFDC) over a time period, wherein the producing step is carried out in the presence of catalase during a portion of said time period.
Methods for increasing cannabinoid production in cannabis plants
The inventive technology relates to systems and methods for enhanced in vivo production, accumulation and modification of cannabinoids. In one embodiment, the invention may include systems and methods for enhanced in vivo biosynthesis of chemically-modified water-soluble cannabinoids in a whole plant, or a cell suspension culture system.
ENTERIC AEROBIZATION THERAPY
Agents, kits, and methods that utilize oxygenation to prevent and/or treat infections caused by anaerobic microorganisms are provided. The agents, kits, and methods according to several embodiments utilize oxygenation in the intestinal lumen to prevent and/or treat infections caused by anaerobic bacteria. The agents, kits, and methods can be utilized to prevent and/or treat anaerobic bacterial infections of the intestinal lumen by enteric aerobization therapy.