Patent classifications
C12Y202/01001
COMPOSITIONS, SYSTEMS, AND METHODS FOR ARTIFICIAL CARBON FIXATION, CHEMICAL SYNTHESIS, AND/OR PRODUCTION OF USEFUL PRODUCTS
Provided herein are production systems and methods to produce a plurality of organic carbon-containing compounds from carbon dioxide, including glyceraldehyde 3-phosphate, glucose, cellulose, and starch, using stabilized enzymes in aqueous media.
Engineered biosynthetic pathways for production of histamine by fermentation
The present disclosure describes the engineering of microbial cells for fermentative production of histamine and provides novel engineered microbial cells and cultures, as well as related histamine production methods.
Method of producing lipid
A method of improving photosynthetic ability of an alga, containing enhancing expression of a transketolase and a fructose-1,6-bisphosphate aldolase.
IMPROVED FERMENTING ORGANISM FOR ETHANOL PRODUCTION
The present invention relates to processes for producing ethanol comprising saccharifying cellulosic or starch-containing material and fermenting the saccharified material with a fermenting microorganism to produce ethanol. The fermenting organism is Saccharomyces cerevisiae strain MBG5151 (deposited under Accession No. Y-67971 at the Agricultural Research Service Culture Collection (NRRL), Illinois 61604 U.S.A.), Saccharomyces cerevisiae strain MBG5248 (deposited under Accession No. Y-68015 at the Agricultural Research Service Culture Collection (NRRL), Illinois 61604 U.S.A.) or a fermenting organism that has properties that the same or about the same as that of Saccharomyces cerevisiae MBG5151 or MBG5248.
RECOMBINANT STRAIN FOR PRODUCING SHIKIMIC ACID, AND CONSTRUCTION METHOD AND USE THEREOF
The present invention relates to a recombinant strain for producing shikimic acid, in which a target gene that regulates the asymmetric cell division and target genes that regulate the shikimic acid production are expressed The target gene that regulates the asymmetric cell division includes cytoskeletal protein PopZ coding gene popZ, and the target genes that regulate the shikimic acid production include DAHP synthase coding gene aroG, 3-dehydroquinate synthase coding gene aroB, and transketolase coding gene tktA. The recombinant strain of the present invention realizes the de novo synthesis of shikimic acid using glucose as a substrate, with a low cost. After fermentation with the strain in a 7.5 L fermentor, the highest production of shikimic acid is 88.1 g/L, the yield is 0.33 g/g, and the production intensity of shikimic acid is 1.1 g/L/h.
MODULAR PLATFORM FOR PROGRAMMABLE SPATIOTEMPORAL BIOMOLECULE CLUSTERING WITH APPLICATIONS INCLUDING ENHANCED METABOLIC YIELD
Provided herein are programmable condensate protein systems and nucleic acid constructs encoding the same. The protein system enables modular targeting of proteins of interest. Protein-peptide interaction domains (PPIDs) are incorporated to functionalize engineered condensates with the attributes of the recruited protein, resulting in a modular system that allows for diverse facile and reprogrammable applications, including in enzyme clustering of metabolic pathways. Colocalizing specific metabolic enzymes in these condensates results in functionalized organelles with which can be used to manipulate the output of engineered metabolic pathways for the production of a pharmaceutical precursor.
ERYTHRITOL PRODUCING SAPROTROPH
The present invention pertains to a genetically modified saprotroph for the biotechnological production of erythritol and a method for the production of erythritol using said genetically modified saprotroph.
Microorganism for producing a mycosporine-like amino acid and method for producing a mycosporine-like amino acid using the same
The present disclosure relates to a microorganism for producing a mycosporine-like amino acid, and a method for producing a mycosporine-like amino acid using the microorganism. The microorganism of the present disclosure shows an improved ability for producing a mycosporine-like amino acid and thus can be effectively used in the production of a mycosporine-like amino acid.
Cell-free metabolic pathway for glucose metabolism with a molecular purge valve
Provided is an engineered pathway that can function in a cell-free system, cellular system or a combination thereof to convert a sugar to a chemical or biofuel.
A MICROORGANISM PRODUCING A MYCOSPORINE-LIKE AMINO ACID AND A METHOD FOR PRODUCING A MYCOSPORINE-LIKE AMINO ACID USING THE SAME
The present disclosure relates to a microorganism producing a mycosporine-like amino acid and a method for producing a mycosporine-like amino acid using the microorganism.
Since the microorganism of the present disclosure has an increased mycosporine-like amino acid-producing ability, it can be effectively used in producing mycosporine-like amino acids.