Patent classifications
A01N43/46
Non-crystallizing cannabidiol blends
A non-crystallizing blend includes cannabidiol (CBD) and cannabidiolic acid (CBDA). A method of forming a non-crystallizing blend of CBD and CBDA includes obtaining a CBD isolate including at least 80% by weight CBD, obtaining a CBDA isolate including at least 80% by weight CBDA, and combining and mixing the CBD isolate and the CBDA. A method of treating a condition includes administering a therapeutically effective amount of a non-crystallizing blend of CBD and CBDA to a patient in need thereof.
Stable pharmaceutical formulation
The present invention relates to a stable formulation of cyclophosphamide comprising a therapeutically effective amount of cyclophosphamide, ethanol as solvent, polyethylene glycol as the solvent, and optionally, monothioglycerol as the anti-oxidant, wherein the composition is stable over its shelf life.
PESTICIDES AND INSECT REPELLENTS
Provided herein are screening methods for identifying compounds for use as repellents, e.g., as alternatives to DEET, and as pesticides. Further provided are one or more compounds identified using the screening methods described herein, and compositions containing such compounds.
Diaminopyrimidine derivatives and processes for the preparation thereof
The present invention provides a diaminopyrimidine derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, a pharmaceutical composition comprising the same, and a use thereof. The diaminopyrimidine derivative or its pharmaceutically acceptable salt functions as a 5-HT.sub.4 receptor agonist, and therefore can be usefully applied for preventing or treating dysfunction in gastrointestinal motility, one of the gastrointestinal diseases, such as gastroesophageal reflux disease (GERD), constipation, irritable bowel syndrome (IBS), dyspepsia, post-operative ileus, delayed gastric emptying, gastroparesis, intestinal pseudo-obstruction, drug-induced delayed transit, or diabetic gastric atony.
Attractants for rats
A rat attractant composition is disclosed which includes one or more isolated additives. The composition is attractive to at least rats of the species Rattus norvegicus. Devices including the rat attractant composition and methods of using a rat attractant composition are also disclosed.
Attractants for rats
A rat attractant composition is disclosed which includes one or more isolated additives. The composition is attractive to at least rats of the species Rattus norvegicus. Devices including the rat attractant composition and methods of using a rat attractant composition are also disclosed.
Compositions based on propolis nanocapsules which can be used as carriers for substances of interest, methods for producing same and use thereof
A process for obtaining compositions constituted by propolis nanoparticles is disclosed. The nanoparticles are optionally associated to a substance of interest such as active ingredients, and, optionally, substances of secondary effect such as synergists and adjuvants. The process includes preparing a fraction A, which consists of propolis extract dissolved in an organic solvent, to which stabilizer and/or emulsifier may be added, and, optionally, substances of interest and/or of secondary effect; ii) preparing a fraction B, aqueous phase, constituted by: (ii.1) water; or (ii.2) an aqueous solution or dispersion, to which stabilizer and/or emulsifier may be added; (iii) dropping the fraction A onto the fraction B or vice versa; iv) homogenizing the mixture by stirring and spontaneous formation of nanoparticles with average size from 1 to 1000 nm in a dispersion; and v) optionally (v-1) removing organic solvent and/or (v-2) drying the nanodispersion.
Compositions based on propolis nanocapsules which can be used as carriers for substances of interest, methods for producing same and use thereof
A process for obtaining compositions constituted by propolis nanoparticles is disclosed. The nanoparticles are optionally associated to a substance of interest such as active ingredients, and, optionally, substances of secondary effect such as synergists and adjuvants. The process includes preparing a fraction A, which consists of propolis extract dissolved in an organic solvent, to which stabilizer and/or emulsifier may be added, and, optionally, substances of interest and/or of secondary effect; ii) preparing a fraction B, aqueous phase, constituted by: (ii.1) water; or (ii.2) an aqueous solution or dispersion, to which stabilizer and/or emulsifier may be added; (iii) dropping the fraction A onto the fraction B or vice versa; iv) homogenizing the mixture by stirring and spontaneous formation of nanoparticles with average size from 1 to 1000 nm in a dispersion; and v) optionally (v-1) removing organic solvent and/or (v-2) drying the nanodispersion.
Antimicrobial coatings and methods of making and using thereof
Disclosed are antimicrobial articles and surfaces, as well as methods of making such articles and surfaces.
Antimicrobial coatings and methods of making and using thereof
Disclosed are antimicrobial articles and surfaces, as well as methods of making such articles and surfaces.