A method of communicating with an ingestible capsule includes detecting the location of the ingestible capsule, focusing a multi-sensor acoustic array on the ingestible capsule, and communicating an acoustic information exchange with the ingestible capsule via the multi-sensor acoustic array. The ingestible capsule includes a sensor that receives a stimulus inside the gastrointestinal tract of an animal, a bidirectional acoustic information communications module that transmits an acoustic information signal containing information from the sensor, and an acoustically transmissive encapsulation that substantially encloses the sensor and communications module, wherein the acoustically transmissive encapsulation is of ingestible size. The multi-sensor array includes a plurality of acoustic transducers that receive an acoustic signal from a movable device, and a plurality of delays, wherein each delay is coupled to a corresponding acoustic transducer. Each delay may be adjusted according to a phase of a signal received by the corresponding acoustic transducer.

Infrared imaging devices are provided which are configured to implement side-scan infrared imaging for, e.g., medical applications. For example, an imaging device includes a ring-shaped detector element comprising a circular array of infrared detectors configured to detect thermal infrared radiation, and a focusing element configured to focus incident infrared radiation towards the circular array of infrared detectors. The imaging device can be an ingestible imaging device (e.g., swallowable camera) or the imaging device can be implemented as part of an endoscope device, for example.

A guidance apparatus includes: a magnetic field generator configured to generate a magnetic field that acts on a magnet; a magnetic field shielding material configured to shield the magnetic field generated by the magnetic field generator; an operation input device configured to receive an input of at least one of a target position and a target posture for guiding a position and a posture of a capsule medical apparatus; and a controller configured to control the magnetic field generator to generate a magnetic field that has been corrected to offset or reduce a deviation amount of the position or the posture of the capsule medical apparatus with respect to the target position or the target posture, caused by distortion, due to the magnetic field shielding material, of a magnetic field for guiding the capsule medical apparatus to at least one of the target position and the target posture.

Described embodiments include a capsule, including a cyclically everting sleeve shaped to define a sleeve interior, a fluid, configured to facilitate the everting of the sleeve, contained within the sleeve interior, and a plurality of electrically-conductive coils coupled to the sleeve. The coils are configured to, when at least two of the coils are magnetized, advance the capsule within a lumen by applying an everting force to the sleeve. Other embodiments are also described.

A method of analysis using mass spectrometry and/or ion mobility spectrometry is disclosed comprising: (a) using a first device to generate smoke, aerosol or vapour from a target in vitro or ex vivo cell population; (b) mass analysing and/or ion mobility analysing said smoke, aerosol or vapour, or ions derived therefrom, in order to obtain spectrometric data; and (c) analysing said spectrometric data in order to identify and/or characterise said target cell population or one or more cells and/or compounds present in said target cell population.

Photobiomodulation can be used to treat disorders of the gastrointestinal system. The photobiomodulation can be delivered by an intraluminal device (which can be within the gastrointestinal system) that includes at least one light delivery device configured to provide photobiomodulation; at least one photodetector device to measure reflectance based on the photobiomodulation; a processor to receive a reflectance signal from the at least one photodetector device based on the reflectance measured by the at least one photodetector device and process the reflectance signal; and a wireless transceiver coupled to the processor to transmit at least a portion of the processed reflectance signal. The wireless transceiver can communicate with an external device that includes a wireless transceiver to receive the at least the portion of the processed reflectance signal.

Provided is a capsule endoscope. The capsule endoscope includes: an imaging device configured to perform imaging on a digestive tract in vivo to generate an image; an artificial neural network configured to determine whether there is a lesion area in the image; and a transmitter configured to transmit the image based on a determination result of the artificial neural network.

A pellet for testing distal colonic and anorectal function. In one embodiment the pellet comprises a bag comprising the exterior of the pellet wherein the bag is comprised of a polymer that is reactive with a catalyst to form a more solid-like substance. In another embodiment, the pellet may comprise one of a grapheme layer, a wavelength transducer, or a magnetically attractive element. In another embodiment the pellet may comprise a telescopic extender and further comprise a telescope bad coupled to the telescopic extender.

A system and method for controlling a capsule endoscope is provided. The control method includes: measuring a magnetic field value of the environment in which the capsule endoscope is subjected; obtaining a critical magnetic field value for suspension of the capsule endoscope according to the magnetic field value; adjusting a traction force on the capsule endoscope according to the critical magnetic field value for suspension; and controlling the movement of the capsule endoscope in a horizontal and/or vertical direction, wherein the movement of the first magnet is controlled by moving the second magnet, and the capsule endoscope is in a quasi-suspended state as moving in the horizontal and/or vertical direction. The system and method reduce friction between the capsule endoscope and wall of the target area during movement by controlling the capsule endoscope in a quasi-suspended state, which makes the scanning of the target area more accurate.

A medical capsule, comprising an enclosure, the enclosure comprising an opening at one end along an axial direction; a PCB group and a functional unit which are arranged inside the enclosure; wherein the PCB group comprises a plurality of PCBs which are connected through flexible printed circuits and are spaced from each other, and the functional unit comprises a battery unit electrically connected to the PCB; and a pressure detection unit, comprising a pressure transmission film assembled at the opening, a pressure sensor positioned in the enclosure, and a pressure collecting and processing circuit board electrically connected to the pressure sensor, wherein the pressure collecting and processing circuit board is connected to one of the PCBs through a flexible printed circuit. The medical capsule is simple in structure, easy to equip and allows for expansion of functions as needed.