Described here are methods and systems for the manipulation of ovarian tissues. The methods and systems may be used in the treatment of polycystic ovary syndrome (PCOS). The systems and methods may be useful in the treatment of infertility associated with PCOS.

Systems and methods for delivering energy to passageways in a patient, such as airways in the lung of a patient for treating asthma. One embodiment of a method for delivering energy to a passageway comprises positioning an access device in a lung airway of a patient and advancing an elongated body of a treatment device along the access device until an energy delivery unit at a distal portion of the elongated body projects from the access device. The method can further include expanding the energy delivery unit such that energy delivery elements contact a sidewall of the airway and activating an energy supply coupled to the treatment device such that energy is delivered to the sidewall of the airway. A single person physically operates both the access device and the treatment device while expanding the energy delivery unit and activating the energy supply.

An assembly for radiofrequency ablation of tissue. The assembly includes a cannula and an electrode. A cannula body includes a cannula bend, and a single side opening radially positioned on an outer side of the cannula body. The outer side may be opposite an inner side on which a tip terminates at a point. A cannula hub may include indicia on a face that corresponds to the inner side. An electrode bend of an electrode body may be formed at a same axial location along its length as the cannula bend is formed along the length of the cannula body. The electrode may include a thermocouple near a distal end of the electrode body to be either directed through the single side opening in a dual active tip mode, or seated in a distal section of the cannula body in a single active tip mode.

Aspects of the present disclosure are directed to flexible high-density mapping catheters with a high-density array of mapping electrodes. These mapping catheters may be used to detect electrophysiological characteristics of tissue in contact with the electrodes, and may be used to diagnose cardiac conditions, such as cardiac arrhythmias for example.

An electrode unit of the invention includes: an electrode including one end and another end, the other end including a free end; and an electrode supporting portion that supports the one end of the electrode. The electrode is disposed in a second plane that is different from a first plane in which the electrode supporting portion is moved to advance or withdraw when the electrode supporting portion is moved to advance or withdraw in a direction along a longitudinal axis of the electrode supporting portion, and the electrode is supported by the electrode supporting portion via a flexed portion projecting from the first plane to the second plane.

A device for minimally invasive, inter-layer surgical procedures advantageously forms a wedge for advancing between adjacent tissue layers and provides a jaw that can be actuated to create a working space for a cutting tool and other instruments within a plane between the tissue layers. The device may also usefully employ an open or wireframe structure for the opposing jaws to preventing tissue or fluid accumulation between the jaws and maximize visibility around the surgical site.

A needle electrode deployment shaft includes a central member and a plurality of needle electrodes. The central member has a plurality of needle advancement channels formed therein. The needle electrodes are disposed within the advancement channels and each advancement channel terminates in a ramp portion which deflects the needles radially outwardly as they are axially advanced. The ramps may be spirally or acutely configured in order to increase the distance through which the needles may be bent as they are axially advanced. Additionally, the central member may have a radially reduced distal tip in order to decrease tissue insertion forces.

A system for modulating bladder function is disclosed. A system for evaluating the electrophysiological function of a bladder is disclosed. Methods for performing a controlled surgical procedure on a bladder are disclosed. A system for performing controlled surgical procedures in a minimally invasive manner is disclosed. An implantable device for monitoring and/or performing a neuromodulation procedure on a bladder is disclosed.

Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a catheter shaft. An expandable member may be coupled to the catheter shaft. The expandable member may be capable of shifting between a folded configuration and an expanded configuration. A plurality of flexible elements may be attached to the expandable member, with a plurality of electrode assemblies disposed on the flexible elements. The flexible elements may have a grooved substrate.