A cooling element includes a frame including one or more datums. The cooling element also includes a first window including a first proximal surface and a first distal surface. The first window is sealed to the frame. The cooling element further includes a second window sealed to the frame. The second window includes a second proximal surface and a second distal surface. The second window is configured to contact a target tissue or a tissue adjacent to the target tissue via the second distal surface. The cooing element also includes a coolant chamber located between the first distal surface of the first window and the second proximal surface of the second window and configured to receive a coolant. The first window, the second window and the coolant chamber are configured to receive and electromagnetic radiation (EMR), and transmit a portion of the received EMR to the target tissue.

A hand piece for delivering energy from a laser to a target through a fiber tip includes an elongated handle having a proximal end and a distal end. An axial bore traverses the handle along a longitudinal axis thereof. A fiber tip holding mechanism is fixed within the axial bore of the handle and includes a forward section fixed with the handle, a spring, and a rear section that includes a hollow collet projecting forward therefrom that traverses the spring and the forward section. The forward section is slidable rearward towards the rear section to compress the spring in a rear position. The spring urges the forward section forward into a forward position. A chuck is fixed with the forward end of the fiber tip holding mechanism and includes a tapered sleeve and two or more oppositely tapered jaws.

Proposed are a laser feedback device for irradiation to an eyeball and a laser feedback method using the same, the laser feedback device comprising: a guide beam irradiation unit for irradiating a guide beam to an eyeball of a patient; a reflection unit positioned adjacent to the guide beam irradiation unit; a laser irradiation unit for irradiating a laser into the eyeball; an image acquisition unit that receives a reflection beam reflected from the eyeball and refracted through the reflection unit and acquires at least one retinal image of the retina of the eyeball; and an image mapping unit that maps at least one retinal image to construct a macular image which is a full image of the macula of the eyeball.

Systems, devices, and methods for transvascular ablation of target tissue are disclosed herein. The devices and methods may, in some examples, be used for splanchnic nerve ablation to increase splanchnic venous blood capacitance to treat at least one of heart failure and hypertension. For example, the devices disclosed herein may be advanced endovascularly to a target vessel in the region of a thoracic splanchnic nerve (TSN), such as a greater splanchnic nerve (GSN) or a TSN nerve root. Also disclosed are method of treating heart failure, such as HFpEF, by endovascularly ablating a thoracic splanchnic nerve to increase venous capacitance and reduce pulmonary blood pressure.

The present invention relates to Fiber Feedback (FFB) technology, and provides a method and system for estimating distance between a fiber end and a target. The method includes illuminating, by a Light Emitting, Transmitting and Detecting (LETD) system, the target with laser light of different wavelengths having low and high-water absorption coefficients, using different laser light sources, as well as receiving a returned signal corresponding to the incident laser light of different wavelengths, and detecting the returned signal to measure intensity values of the returned signal of a specific wavelength. Using the measured intensity values, a processing unit may estimate distance between the fiber end and the target. The present invention enables accurate estimation of distance between a fiber end and a target, and also provides a robust distance estimation technique which is compatible with different types of targets.

The present disclosure is directed towards a medical instrument. The medical instrument includes a housing and an end effector assembly operably connected to the housing. The end effector assembly includes first and second jaw members each having a tissue contacting surface, at least one of the first and second jaw members movable between a first, spaced-apart position and a second proximate position, wherein in the second position, the jaw members cooperate to define a cavity configured to receive tissue between the jaw members. The end effector also includes at least one light-emitting element coupled to at least one of the first and second jaw members, the at least one light-emitting element adapted to deliver light energy to tissue grasped between the first and second jaw members to treat the tissue.

A dental procedure performed on target tissue without anesthetic or anesthesia including preconditioning the target tissue using a laser device constructed to produce light in a wavelength range of 2750 nm to 11500 nm, to provide an energy fluence in a range of 50 J/cm.sup.2 to 100 J/cm.sup.2, and to operate in a free running pulsed mode providing 60 μm bursts at a frequency of at least 50 Hz. Preconditioning includes selecting a combination of average optical output power and preconditioning time to administer low level laser therapy. The laser device is adjusted to deliver light through the light guide of the laser device at the selected average optical output power. Light delivered through the light guide of the adjusted laser device is directed toward the target tissue for the selected preconditioning time providing analgesia to the target tissue. Oral tissue is removed from the preconditioned target tissue during analgesia.

A dental procedure performed on target tissue without anesthetic or anesthesia including preconditioning the target tissue using a laser device constructed to produce light in a wavelength range of 2750 nm to 11500 nm, to provide an energy fluence in a range of 50 J/cm.sup.2 to 100 J/cm.sup.2, and to operate in a free running pulsed mode providing 60 μm bursts at a frequency of at least 50 Hz. Preconditioning includes selecting a combination of average optical output power and preconditioning time to administer low level laser therapy. The laser device is adjusted to deliver light through the light guide of the laser device at the selected average optical output power. Light delivered through the light guide of the adjusted laser device is directed toward the target tissue for the selected preconditioning time providing analgesia to the target tissue. Oral tissue is removed from the preconditioned target tissue during analgesia.

Systems, devices, and methods for transvascular ablation of target tissue are disclosed herein. The devices and methods may, in some examples, be used for splanchnic nerve ablation to increase splanchnic venous blood capacitance to treat at least one of heart failure and hypertension. For example, the devices disclosed herein may be advanced endovascularly to a target vessel in the region of a thoracic splanchnic nerve (TSN), such as a greater splanchnic nerve (GSN) or a TSN nerve root. Also disclosed are method of treating heart failure, such as HFpEF, by endovascularly ablating a thoracic splanchnic nerve to increase venous capacitance and reduce pulmonary blood pressure.

Systems, devices, and methods for transvascular ablation of target tissue are disclosed herein. The devices and methods may, in some examples, be used for splanchnic nerve ablation to increase splanchnic venous blood capacitance to treat at least one of heart failure and hypertension. For example, the devices disclosed herein may be advanced endovascularly to a target vessel in the region of a thoracic splanchnic nerve (TSN), such as a greater splanchnic nerve (GSN) or a TSN nerve root. Also disclosed are method of treating heart failure, such as HFpEF, by endovascularly ablating a thoracic splanchnic nerve to increase venous capacitance and reduce pulmonary blood pressure.