A hemodynamic monitoring system monitors arterial blood pressure of a patient and provides a warning to medical personnel of a predicted future hypotension event of the patient. Waveform analysis is performed on sensed hemodynamic data representative of an arterial pressure waveform of the patient to determine a plurality of hypotension profiling parameters predictive of a future hypotension event for the patient. A set of transformed hypotension profiling parameters is generated based on the hypotension profiling parameters and mean and standard deviation values of the hypotension profiling parameters at a standard mean arterial pressure (MAP) threshold for hypotension and an adjusted MAP threshold for hypotension. A risk score representing a probability of a future hypotension event for the patient is determined based on the set of transformed hypotension profiling parameters. A sensory alarm is invoked to produce a sensory signal in response to the risk score satisfying a predetermined risk criterion.

Provided is a detector assembly for determining a ratio of lactate to pyruvate from dialysis, said detector assembly comprising: a first pump, a dialysis probe, a first tube fluidically coupling the first pump to an inlet of the dialysis probe, an infrared (IR) detector, a second tube fluidically coupling an outlet of the dialysis probe to the IR detector, and a controller. The first pump pumps a perfusate at a first flow rate to the dialysis probe, via the first tube, and to, in turn, pump a dialysate at a second flow from the dialysis probe to the IR detector, via the second tube. The IR detector detects respective absorbances due to lactate and pyruvate in the dialysate, and the controller determines the ratio of lactate to pyruvate in the dialysate.

An information display and control system that enables a fast and easy understanding and management of the status of the patient's dialysis is disclosed. Also disclosed is an information display and control system that enables a fast and easy understanding and management of the status of the patient's cardiovascular and ventilation systems. The system can control management of a patient's dialysis, as well as administration and management of a patient's medication and fluids. The display is organized by goals related to management of patient's dialysis machine, blood flow, dialyzer flow, and patient's body weight. The display is also organized by goals related to management of patient's cardiovascular system, ventilation system, and medications and fluids administration and management. Such goals include urea reduction rate, urea reduction ratio, fractional urea clearance, total urea reduction, dialysis treatment duration, hemodynamics, oxygenation, CO.sub.2 removal, medication status, and fluids status.

A wireless intraluminal device (102) and an associated system for treating and diagnosing patients are provided. In one embodiment, the wireless intraluminal device (102) includes a flexible elongate member (158) including a proximal portion (106) and a distal portion (108); a sensor assembly (116) coupled to the distal portion of the flexible elongate member; a cable (117) coupled to the sensor assembly and extending along the flexible elongate member; and a wireless transceiver (252) positioned within the flexible elongate member, wherein the wireless transceiver is in communication with the sensor assembly via the cable. A wireless communication component (104) wirelessly transmits a sensor measurement collected by the sensor assembly to a sensor measurement processing system (132) via a wireless link (150) for physiological data generation at the sensor measurement processing system.

An example device for determining one or more transient decelerations includes a memory configured to store a sensed pulse rate signal indicative of one or more sensed pulse rates and processing circuitry. The processing circuitry is configured to determine that an amplitude threshold is crossed by a sensed pulse rate signal indicative of one or more sensed pulse rates. The processing circuitry also is configured to, from a time the amplitude threshold is crossed, determine that a pulse rate returns to within a range of a baseline pulse rate within a number of samples or a time period. The processing circuitry is also configured to, based on the pulse rate returning to within the range of the baseline pulse rate, from the time the amplitude threshold is crossed, within the number of samples or the time period, determine a transient deceleration.

Physiological time-series (PTS) data is sampled continuously from patients in the ICU. Here, this data is used to identify and prevent septic shock. The present invention applies statistical modeling and machine learning methods to implement an early warning policy for predicting those patients likely to transition from non-sepsis, early sepsis or sepsis into septic shock. Results demonstrate that the system and method of the present invention can provide higher sensitivity and specificity in this task than any other method reported to date. The present invention triggers an advanced early warning of this pending transition with median value 12.5 hours, giving ample opportunity for physicians to intervene to treat and prevent the patient from developing septic shock.

Method for ascertaining and setting a filling volume of a balloon of a catheter, which is placed in the esophagus of a living being, wherein the balloon is filled and/or emptied using a fluid. According to the invention, the balloon is filled and/or emptied step-by-step using at least two volume steps, a pressure difference between a pressure at the end of an expiration (Pmin) and a pressure at the end of an inspiration (Pmax) is determined for at least two volume steps, a relative pressure difference between Pmin and Pmax is determined, a border range is defined on the basis of the relative pressure difference, and an optimum filling volume is ascertained in consideration of the border range.

Disclosed herein is an automated urinary output monitoring system including urine collection assembly that includes a first drainage tube coupled between a urinary catheter and an interim container, and a second drainage coupled between the interim container and a final container. A scale measures the weight of urine collected in the final container and a display depicts the volume of urine collected in the final container. A vacuum pump can be coupled with the final container to draw urine from the interim container into the final container, and an air vent can isolate the patient from the vacuum within the final container. The system can be configured to wirelessly transmit urine volume data to an external computing device. A gyroscope can be coupled with the scale to determine the orientation of the scale. Logic of the system can calculate urine volume and correlate with the time of day.

Various embodiments concern video patient monitoring with detection zones. Various embodiments can comprise a camera, a user interface, and a computing system. The computing system can be configured to perform various steps based on reception of a frame from the camera, including: calculate a background luminance of the frame; monitor for a luminance change of a zone as compared to one or more previous frames, the luminance change indicative of patient motion in the zone; and compare the background luminance to an aggregate background luminance, the aggregate background luminance based on the plurality of frames. If the background luminance changed by more than a predetermined amount, then the aggregate background luminance can be set to the background luminance, luminance information of the previous frames can be disregarded, and motion detection can be disregarded.

Constructive layout in a container, to provide clean areas for medical and hospital care, such as fractionation of solid and liquid oral drugs (ISO8) and handling of sterile drugs (ISO7), as well as the configuration of the containers for the infusion, diagnosis, surgery, ICU and hemodialysis areas.