In some examples, a device includes a catheter insert elongated body defining a body lumen, the catheter insert elongated body being configured to be at least partially inserted to a catheter lumen defined by a catheter without covering a first fluid opening of the catheter and to form a fluidically tight coupling with the catheter, and one or more sensors positioned on the elongated body. At least one of the one or more sensors are configured to sense a substance of interest. The catheter insert elongated body includes a material that is a substantially non-permeable to the substance of interest.

A fully automated ultrasound apparatus includes a sensor or probe which can be initially manually attached to a side of the neck of a patient, an ultrasound interface to control the sensor and periodically acquire raw ultrasound data, a signal and image processing system to autonomously convert the raw ultrasound data into a measurement that is useful to physicians, and a display to relay the current measurements and measurement history to provide data trends. The sensor can include one or more ultrasound transducers built into a housing. A disposable component can serve to secure the sensor to the neck of the patient and to provide a coupling medium between the sensor and the skin of the patient.

The current invention relates to the use of a neural network to improve the quality of images obtained from light scattered by an intermediate object that scatters light, such as tissue or a frosted screen. The invention relates to a method of imaging a human or animal bode using a nanocrystal array capable of fluorescing upon excitation from light from a near-infrared light source. This invention also relates to detection means and apparatus used in said methods, as well as to quantum dots useful in said use.

A wearable treatment and analysis module is provided. The module is positioned on or near a body surface region of interest. The module provides remote access to sensor data, treatment administration, and/or other health care regimens via a network connection with a user device and/or management system.

A catheter includes: (i) a shaft for insertion into an organ of a patient, (ii) an expandable distal-end assembly, which is coupled to the shaft and includes multiple splines, (iii) at least an ablation electrode, which is configured: (a) to be coupled to a spline of the splines, and (b) when placed in contact with tissue of the organ, to apply an ablation signal to the tissue, and the ablation electrode includes a slot, and (iv) a temperature sensor, which is contained within the slot and is configured, when the ablation electrode is placed in contact with the tissue, to produce a thermal signal indicative of a temperature of the tissue.

An adaptive audio therapy system which detects and processes one or more individuals' conditions to provide adaptive, continuous audio therapy in real-time. The adaptive audio therapy system generally includes a detection device that is typically in physical contact with an individual, such as a pacifier or steering wheel. The detection device may include sensors to detect various conditions of the individual, such as heart rate, respiration rate, temperature, and the like. A computing device receives and processes the various conditions detected by the sensors. Based on the detected conditions, the computing device provides audio therapy which is adaptive to the condition of the patient and which is continuously adapted in real-time.

A wearable device includes a processor and a lower module. The lower module includes a pressure sensor for detecting a mechanical movement of a skin that covers an artery. The mechanical movement of the skin is due to blood flow through the artery. The processor is configured to receive skin movement information from the movement sensor; calculate a pulse front velocity (PFV), which is a velocity of a blood wave as the blood wave passes under the pressure sensor; estimate a pulse wave velocity (PWV) using the PFV; and estimate the blood pressure using the PWV.

A biosensor assembly that measures multiple physical parameters is disclosed. The biosensor assembly includes a first implantable probe and a first skin contacting electrode. Wherein a first physiological parameter is measured between the first implantable probe and the first skin contactable electrode.

A wearable treatment and analysis module is provided. The module is positioned on or near a body surface region of interest. The module provides remote access to sensor data, treatment administration, and/or other health care regimens via a network connection with a user device and/or management system.

Described herein are systems and methods for performing optical signal analysis and lesion predictions in ablations. A system includes a catheter coupled to a plurality of optical fibers via a connector that interfaces with a computing device. The computing device includes a memory and a processor configured to receive optical measurement data of a portion of tissue from the catheter. The processor identifies one or more optical properties of the portion of tissue by analyzing the optical measurement data and determines a time of denaturation of the portion of tissue based on the one or more optical properties. A model is created to represent a correlation between lesion depths and ablation times using the time of denaturation, the one or more optical properties, and the predetermined period of time. A predicted lesion depth for a predetermined ablation time is generated using the model.