A scanner for scanning a dental site comprises a base, a detector mounted to the base, and an optical element to redirect light reflected off of the dental site towards the detector along a detection axis in a first direction. Two or more flexures couple the optical element to the base, wherein the two or more flexures maintain an alignment of the optical element to the detector with changes in temperature.

Systems, methods, and apparatus for differential phase contrast microscopy by transobjective differential epi-detection of forward scattered light are provided. In some embodiments, a microscope objective comprises: a housing with mounting threads at a second end; optical components defining an optical axis, comprising: an objective lens mounted at a first end, configured to collect light from a sample placed in a field of view, the plurality of optical components create a pupil plane at a first distance along the optical axis at which rays having the same angle of incidence on the objective lens converge at the same radial distance from the optical axis; a photodetector within the housing offset from the optical axis at a second distance along the optical axis; and another photodetector within the housing at second distance along the optical axis and offset from the optical axis in the opposite direction from the first photodetector.

Provided herein are systems, methods, and media capable of determining estimated force applied on a target tissue region to enable tactile feedback during interaction with said target tissue region.

A scanner for scanning a dental site comprises a base, a detector mounted to the base, and an optical element to redirect light reflected off of the dental site towards the detector along a detection axis in a first direction. Two or more flexures couple the optical element to the base, wherein thermal expansion or contraction of the optical element with respect to at least one of the detector or the base bends each flexure of the two or more flexures in a respective second direction without bending the flexure in a respective third direction approximately perpendicular to the first direction and the respective second direction, wherein the two or more flexures maintain an alignment of the optical element to the detector with changes in temperature.

An optical probe assembly as a confocal endomicroscope includes an optical focusing stage that focuses an output beam onto a sample and a mirror scanning stage that is movable for scanning the output beam in both a lateral two dimensional plane and an axial direction, using a side-view configuration. The side-view configuration allows for output beam illumination and fluorescent imaging of the sample with greater imaging resolution and improved access to hard to reach tissue within a subject.

A scanner includes a camera, a light source for generating a probe light incorporating a spatial pattern, an optical system for transmitting the probe light towards the object and for transmitting at least a part of the light returned from the object to the camera, a focus element within the optical system for varying a position of a focus plane of the spatial pattern on the object, unit for obtaining at least one image from said array of sensor elements, unit for evaluating a correlation measure at each focus plane position between at least one image pixel and a weight function, a processor for determining the in-focus position(s) of each of a plurality of image pixels for a range of focus plane positions, or each of a plurality of groups of image pixels for a range of focus plane positions, and transforming in-focus data into 3D real world coordinates.

The present invention is a Miniature Vein Enhancer, for use in imaging the subcutaneous veins of a target area of a patient by a practitioner. The miniature vein enhancer includes a Miniature Projection Head that is secured to a tourniquet, where the tourniquet may be mounted to the bicep of a patient. The Miniature Projection Head includes a housing, and apparatus that images subcutaneous veins of the target area, and projects the image(s) of the veins onto the target area to overlie the subcutaneous veins, which aids the practitioner in pinpointing a vein location for a venipuncture procedure such as an intravenous drip, blood test, and the like.

The present invention provides method for monitoring physiological status of an organ in a subject by monitoring morphological changes over time in transplanted tissue on an eye of the subject.

In accordance with some embodiments of the disclosed subject matter, systems, methods, and media for selectively presenting images captured by confocal laser endomicroscopy (CLE) are provided. In some embodiments, a method comprises: receiving images captured by a CLE device during brain surgery; providing the images to a convolution neural network (CNN) trained using at least a plurality of images of brain tissue captured by a CLE device and labeled diagnostic or non-diagnostic; receiving an indication, from the CNN, likelihoods that the images are diagnostic images; determining, based on the likelihoods, which of the images are diagnostic images; and in response to determining that an image is a diagnostic image, causing the image to be presented during the brain surgery.

The present disclosure relates to plasma generation systems which utilize plasma for semiconductor processing. The plasma generation system disclosed herein employs a hybrid matching network. The plasma generation system includes a RF generator and a matching network. The matching network includes a first-stage to perform low-Q impedance transformations during high-speed variations in impedance. The matching network includes a second-stage to perform impedance matching for high-Q impedance transformations. The matching network further includes a sensor coupled to the first-stage and the second-stage to calculate the signals that are used to engage the first and second-stages. The matching network includes a first-stage network that is agile enough to tune each state in a modulated RF waveform and a second-stage network to tune a single state in a RF modulated waveform. The plasma generation system also includes a plasma chamber coupled to the matching network.