A surgical vision system for imaging heat capacity and cooling rate of tissue has an infrared source configured to provide infrared light to tissue, the infrared light sufficient to heat tissue, and an infrared camera configured to provide images of tissue at infrared wavelengths. The system also has an image processing system configured to determine, from the infrared images of tissue, a cooling or heating rate at pixels of the images of tissue at infrared wavelengths and to display images derived from the cooling rate at the pixels.

Systems for confocal Raman spectroscopy of points of interest or regions of interest with concurrent imaging are disclosed. The imaging may be used for real time selection of points of interest or regions of interest for Raman spectroscopy and to monitor for unwanted motions of a sample while Raman spectra are acquired. Disclosed embodiments apply Reflectance confocal microscopy (RCM) in a confocal Raman spectroscopy system. A single laser may be used as a light source for both RCM and micro-Raman spectroscopy. A Faraday optical isolator may be applied to extract RCM signals for imaging Systems as described herein have example application for ex vivo sample and in vivo skin measurement.

An apparatus device may include a bio-impedance sensor configured to take a bio-impedance measurement from a body of an individual, an optical sensor configured to take an optical measurement from the body of the individual, and a processing device configured to receive a first bio-impedance measurement from the bio-impedance sensor taken during a first period of time and a first optical measurement from the optical sensor taken during the first period of time, receive first location information of the individual during the first period of time, determine a first correlation between a physiological parameter and at least one of the first location, the first bio-impedance measurement, or the first optical measurement, and determine a first level of the physiological parameter based on the first correlation.

The present disclosure relates to optical methods and devices based on pulsate behavior of blood and optical absorption spectroscopy to measure the level of water and/or other substances or compounds, such as an alcohol or lipid, in the blood and the tissues surrounding blood vessels and arteries.

Systems and methods for detecting data acquisition conditions using color-based penalties can include a computing device obtaining a sequence of images acquired by a photodetector. The computing device can determine, for each pixel position of a plurality of pixel positions associated with the sequence of images, a respective penalty score indicative of a similarity between a color value of a pixel of the pixel position and a desired color value. The desired color value can represent a color property of light emitted from body parts of users when placed opposite to the photodetector. The computing device can determine, using penalty scores of the plurality of pixel positions, a relative position of a body part of a user with respect to a desired position.

An adjustable measurement device is described that may include a housing, a power supply, a processor, a communication device, an elastic coupling member, a physiological sensor, and/or a clamp. The housing may be configured to attach to a wearable band that is wearable by a subject. The housing may include a chamber within the housing. The power supply, the processor, the communication device, the elastic coupling member, and or the physiological sensor may be disposed within the chamber. The elastic coupling member may couple the physiological sensor to the housing. A force exerted by the elastic coupling member on the physiological sensor may be in a direction through an opening towards a body part of a subject. As the subject wears the wearable band and the housing is coupled to the wearable band, the physiological sensor may be adjacent to or contact the subject.

One aspect of the invention relates to a method for intraoperative assessment of parathyroid gland viability in a surgery. The method includes diffusing a beam of light onto a tissue surface of a parathyroid gland of a patient to illuminate the tissue surface; acquiring images of the illuminated tissue surface, where each of the acquired images includes a speckle pattern; and processing the acquired images to obtain speckle contrast images for the intraoperative assessment of parathyroid gland viability.

An imaging apparatus including a light source is provided. The imaging apparatus includes a light-emitting device and a photoelectric conversion device in a pixel, and a pixel circuit has a function of outputting third data generated by multiplying obtained first data by second data (weight). Calculating the third data externally enables more detailed information on a subject with respect to a specific wavelength to be obtained. In addition, reading out collectively a plurality of pixels to which proper weight is given enables output of difference data between pixels and the like, which allows external calculation to be omitted.

Arrangements and methods are provided for obtaining information associated with an anatomical sample. For example, at least one first electro-magnetic radiation can be provided to the anatomical sample so as to generate at least one acoustic wave in the anatomical sample. At least one second electro-magnetic radiation can be produced based on the acoustic wave. At least one portion of at least one second electro-magnetic radiation can be provided so as to determine information associated with at least one portion of the anatomical sample. In addition, the information based on data associated with the second electro-magnetic radiation can be analyzed. The first electro-magnetic radiation may include at least one first magnitude and at least one first frequency. The second electro-magnetic radiation can include at least one second magnitude and at least one second frequency. The data may relate to a first difference between the first and second magnitudes and/or a second difference between the first and second frequencies. The second difference may be approximately between −100 GHz and 100 GHz, excluding zero.

An endoscope with an optical channel is held and positioned by a robotic surgical system. A capture unit captures (1) a visible first image at a first time and (2) a visible second image combined with a fluorescence image at a second time. An image processing system receives (1) the visible first image and (2) the visible second image combined with the fluorescence image and generates at least one fluorescence image. A display system outputs an output image including an artificial fluorescence image.