The present disclosure relates to a device, method and system for calculating, estimating, or monitoring the blood pressure of a subject based on physiological features and personalized models. At least one processor, when executing instructions, may perform one or more of the following operations. A first signal representing a pulse wave relating to heart activity of a subject may be received. A plurality of second signals representing time-varying information on a pulse wave of the subject may be received. A personalized model for the subject may be designated. Effective physiological features of the subject based on the plurality of second signals may be determined. A blood pressure of the subject based on the effective physiological features and the designated model for the subject may be calculated.

The present invention relates to a positioning and exposure device (1) for the defined arrangement on at least one body part (2, 3) of a living being (4) and for exposing the body part (2, 3) to radiation for determining at least one vital parameter of the living being (4). The positioning and exposure device (1) here comprises at least: a guiding and support structure (6) for delimiting an examination area (8), wherein the body part (2) can be positioned during exposure in the examination area (8), wherein the guiding and support structure (6) in a section (10) bounding the examination area (8) forms at least one radiation input area (12), wherein radiation can be introduced through the radiation input area (12) into the examination area (8) and wherein the guiding and support structure (6) forms a radiation exit area (16) in a further portion (14) delimiting the examination area (8), wherein at least part of the radiation which can be introduced through the radiation input area (12) into the examination area (8) can be guided out of the examination area (8) through the radiation exit area (16), and wherein a first elongate optical guide (18) is arranged in the path (20) of the radiation at least before entry into the examination area (8), wherein the first optical guide (18) is curved at least in sections for at least one deflection of the path (20) of the radiation which can be introduced into the first optical guide (18).

The invention comprises a method for estimating state of a cardiovascular system, comprising the steps of: providing a cardiac analyzer, comprising: a blood pressure sensor, the blood pressure sensor generating a time-varying pressure state waveform output from a portion of a person; a system processor connected to the blood pressure sensor; and a dynamic state-space model of a cardiovascular system, the system processor receiving cardiovascular input data, from the blood pressure sensor, related to a transient pressure state of the cardiovascular system, where at least one probabilistic model, of the dynamic state-space model, operating on the time-varying pressure state waveform output generates a probability distribution function to a non-pressure state of the cardiovascular system. The probability distribution function is iteratively updated using synchronized updated time-varying pressure state waveform output from the blood pressure sensor and a non-pressure state output related to a cardiovascular system parameter is generated.

An apparatus for measuring bio-information may include a pulse wave sensor that may measure a pulse wave signal from an object in contact with a measurement surface. The apparatus may include a force sensor that may measure a contact force between the pulse wave sensor and the object. The apparatus may include a fastener configured to fasten the pulse wave sensor to an electronic device such that the pulse wave sensor is rotatable around a center axis in a length direction of the pulse wave sensor. The apparatus may include a processor that may determine a direction in which a measurement region of the pulse wave signal or the measurement surface of the pulse wave sensor is oriented, select a measurement mode from among a plurality of measurement modes, and estimate bio-information of the object.

A sphygmomanometer includes: a sensing cuff that includes a second sheet disposed to face the pressing member's inner circumferential surface and a first sheet facing the second sheet; a fluid storage control part providing a control of supplying and storing the pressure-transmitting fluid into sensing cuff in a worn state wherein the pressing member and sensing cuff are worn on the wrist; and a blood-pressure calculating part calculating a blood pressure based on a pressure of the pressure-transmitting fluid stored in the sensing cuff. The fluid storage control part supplies fluid in the worn state such that the first and second sheets are in contact with each other in a region corresponding to an ulna, a region corresponding to a radius, and a region corresponding to a tendon while first and second sheets are separated from each other in regions corresponding to two arteries that are radial and ulnar arteries.

A method of measuring noninvasive blood pressure includes determining a window for pulse detection for a patient, receiving a pressure signal measured from a measure sensor in a blood pressure cuff, and setting a pulse detection period for each heart beat based on the window and a heart beat indicator indicating at least one heart beat time for the patient. The pressure signal is then examined within each pulse detection period to identify a pressure peak therein. A blood pressure for the patient is determined based on the pressure peaks detected in the pressure signal.

A plurality of modules are simultaneously positioned at locations that correspond to different angiosomes. Each of these modules has a front surface shaped and dimensioned for contacting a person's skin, a plurality of different-wavelength light sources aimed in a forward direction, and a plurality of light detectors aimed to detect light arriving from in front of the front surface. Each module is supported by a support structure (e.g., a strap or a clip) that is shaped and dimensioned to hold the front surface adjacent to the person's skin at a respective position. Perfusion in each of the angiosomes is monitored using these modules, and the surgeon can rely on this information to guide his or her intervention.

The invention disclosed herein relates to improvements in the collection personal health data. It further relates to a Personal Health Monitor (PHM), which may be a Personal Hand Held Monitor (PHHM), that incorporates a Signal Acquisition Device (SAD) and a processor with its attendant screen and other peripherals. The SAD is adapted to acquire signals which can be used to derive one or more measurements of parameters related to the health of a user. The computing and other facilities of the PHM with which the SAD is integrated are adapted to control and analyse signals received from the SAD. The personal health data collected by the SAD may include data related to one or more of blood pressure, pulse rate, blood oxygen level (SpO.sub.2), body temperature, respiration rate, ECG, cardiac output, heart function timing, arterial stiffness, tissue stiffness, hydration, blood viscosity, blood pressure variability, the concentration of constituents of the blood such as glucose or alcohol and the identity of the user.

The present application describes a PHHM of the type described in WO 2013/002165, WO 2014/125431 and International Patent Application No. PCT/EP2015/079888 with improved aspects to find indicators of health, and other improvements that facilitate its construction and calibration.

Systems and methods for acquiring photoplethysmographic (PPG) signals for measuring blood pressure can include a computing device acquiring a sequence of images representing transdermal optical data of a subject, and generating a corresponding sequence of downsampled color frames. The computing device can identify, in each downsampled color frame, a respective central image block representing a central image region of the downsampled color frame and having a first size smaller than a second size of the downsampled color frame. The computing device can generate, for each downsampled color frame, a corresponding color intensity value based on the respective central image block. The computing device can generate, using color intensity values corresponding to the sequence of downsampled color frames, a PPG signal to determine a blood pressure value of the subject.