A pulse measurement device is provided, including a first signal source, a second signal source, two microwave resonators, two mixers, and a signal processing unit. The first signal source and the second signal source output a first high-frequency signal and a second high-frequency signal, respectively. Each of the microwave resonators generates an electric field according to the first high-frequency signal, and senses a variation in the electric field which is interfered by a pulse to obtain a sensing signal. Each of the mixers is coupled to one of the microwave resonators, to mix the sensing signal and the second high-frequency signal to output a down-converted signal. The signal processing unit respectively demodulates amplitudes of the down-converted signals of the two mixers to obtain amplitude signals.

Non-contact biological sensors 1, 2 that detect biological information of a person by electromagnetic waves are provided in a seat 10 on which the person sits. The biological sensors 1, 2 are disposed in the seat 10 at positions away from members A1, A2, A3 (22, 32) which are the members, from among the members that constitute the seat 10, that interfere with the passage of electromagnetic waves. The biological sensors each have a first sensor 100 and a second sensor 200 that emit electromagnetic waves of different frequencies towards the person, and the first sensor 100 is disposed adjacent to the second sensor 200. Due to this configuration, it becomes easier to accurately detect biological information.

A vital sign detection device controls directivities of radio waves A and B toward an irradiation region of a subject to determine the vital signs of the subject. The first directivity is where the vital signs easily appear and the second directivity is where the vital signs are less likely to appear. Noise is reduced by taking a difference between information about a distance to the subject calculated on the basis of the radio wave A having the first directivity and information about a distance to the subject calculated on the basis of the radio wave B having the second directivity received by the receiver.

An object is to accurately determine the presence or absence of a living body. A living body detection device comprises: a signal acquirer that acquires a first signal including a first frequency component that is a frequency component of heartbeat and a second frequency component that is a frequency component of breathing; a filter that attenuates a frequency component higher than the first frequency component based on the first signal to generate a second signal; a frequency analyzer that analyzes a frequency component of the second signal; a variance value calculator that calculates a first variance value of energy of at least one of the first frequency component and the second frequency component based on a result of analysis by the frequency analyzer; a first statistical quantity calculator that calculates a first statistical quantity of the first variance value for a predetermined period; and a determiner that determines presence or absence of a living body based on the first statistical quantity.

Systems and methods for optimizing sensor pressure in blood pressure (BP) measurements using a wearable device are provided. An example method includes recording substantially synchronously photoplethysmogram (PPG) data using a PPG sensor and pressure data using at least one pressure sensor on a wearable device, the wearable device having the PPG sensor, and wherein the at least one pressure sensor is substantially located over a user wrist radial artery while an external force gradually applies and releases pressure a plurality of times to the wearable device, wherein the external force is applied to the radial artery. The PPG data and the pressure data is monitored as the PPG data changes in response to the external force being applied and released multiple times during a period. From the recorded PPG and pressure data, a set data us formed of PPG peak values and pressure values. A curve is fitted through the data set. From the curves apex value a MAP value is determined.

A system including a sensor interface coupled to a processor. The sensor interface is configured to receive and process an analog electrocardiogram signal of a subject and provide a digitized electrocardiogram signal sampled over a first time period and a second time period that is subsequent to the first time period. The processor is configured to receive the digitized electrocardiogram signal, to analyze a frequency domain transform of the digitized electrocardiogram signal sampled over the first and second time periods and determine first and second metrics indicative of metabolic state of a myocardium of the subject during the first and second time periods, respectively, to compare the first and second metrics to determine whether the metabolic state of the myocardium of the subject is improving, and to indicate administration of an intervention to the subject in response to a determination that the metabolic state is not improving.

A system including a sensor interface coupled to a processor. The sensor interface is configured to receive and process an analog electrocardiogram signal of a subject and provide a digitized electrocardiogram signal sampled over a first time period and a second time period that is subsequent to the first time period. The processor is configured to receive the digitized electrocardiogram signal, to analyze a frequency domain transform of the digitized electrocardiogram signal sampled over the first and second time periods and determine first and second metrics indicative of metabolic state of a myocardium of the subject during the first and second time periods, respectively, to compare the first and second metrics to determine whether the metabolic state of the myocardium of the subject is improving, and to indicate administration of an intervention to the subject in response to a determination that the metabolic state is not improving.

An implantable neurostimulator-implemented method for managing tachyarrhythmias through vagus nerve stimulation is provided. An implantable neurostimulator, including a pulse generator, is configured to deliver electrical therapeutic stimulation in a manner that results in creation and propagation (in both afferent and efferent directions) of action potentials within neuronal fibers of a patient's cervical vagus nerve. Operating modes of the pulse generator are stored. A maintenance dose of the electrical therapeutic stimulation is delivered to the vagus nerve via the pulse generator to restore cardiac autonomic balance through continuously-cycling, intermittent and periodic electrical pulses. A restorative dose of the electrical therapeutic stimulation is delivered to prevent initiation of or disrupt tachyarrhythmia through periodic electrical pulses delivered at higher intensity than the maintenance dose. The patient's normative physiology is monitored via a physiological sensor, and upon sensing a condition indicative of tachyarrhythmia, is switched to delivering the restorative dose to the vagus nerve.

An implantable neurostimulator-implemented method for managing tachyarrhythmias through vagus nerve stimulation is provided. An implantable neurostimulator, including a pulse generator, is configured to deliver electrical therapeutic stimulation in a manner that results in creation and propagation (in both afferent and efferent directions) of action potentials within neuronal fibers of a patient's cervical vagus nerve. Operating modes of the pulse generator are stored. A maintenance dose of the electrical therapeutic stimulation is delivered to the vagus nerve via the pulse generator to restore cardiac autonomic balance through continuously-cycling, intermittent and periodic electrical pulses. A restorative dose of the electrical therapeutic stimulation is delivered to prevent initiation of or disrupt tachyarrhythmia through periodic electrical pulses delivered at higher intensity than the maintenance dose. The patient's normative physiology is monitored via a physiological sensor, and upon sensing a condition indicative of tachyarrhythmia, is switched to delivering the restorative dose to the vagus nerve.

According to one embodiment, a detection device includes a substrate, a light detector, a light emitter. The substrate is light-transmissive. The light emitter is provided between the substrate and the light detector. The light emitter includes a first electrode, a light-emitting layer, and a plurality of second electrodes. The first electrode is provided between the light detector and the substrate. The first electrode is light-transmissive. The light-emitting layer is provided between the light detector and the first electrode. The second electrodes are provided between the light detector and the light-emitting layer.