Provided is a method of monitoring a heart rate of an open circulatory system aquatic organism including water fleas, zebrafish, brine shrimp, and the method of evaluating individual response by real time measurement of a heart rate of an aquatic organism and the individual response evaluation apparatus by real time measurement of a heart rate of an aquatic organism according to the present invention may effectively fix the aquatic organism for real time measurement of the heart rate of an aquatic organism, and may measure the heart rate using digital holography to display the heart rate while configuring a data format to allow the corresponding data to be stored for a long time, thereby treating a compound for inducing an individual response, securing a heart rate change in real time by image processing, and then effectively determining the presence or absence of harmfulness due to induction of the individual response.

A system for testing spontaneous social interactions of group-housed mice placed in an experimental apparatus. The system includes a plurality of compartments (101-104) bridged by corridors (105). At least one compartment (101-104) has a perforated partition wall (106,107) separating the compartment into a territory available for mice (106b, 107b) and a territory to be explored by olfaction (106a, 107a). In the territory available for mice (106b, 107b), above the partition wall (106, 107), there is an infrared laser curtain (201). The system also includes a photographic device (202) for acquiring the intersection of a mouse in the light of the infrared curtain. In the territory to be explored by olfaction (106a, 107a), there is a source of olfactory stimuli (203).

An apparatus for sequestering and releasing compounds into the air is provided. The apparatus includes a card with a first side and a second side, and a plurality of compound-sequestering structures affixed to the first side. Each of the plurality of compound-sequestering structures is configured to release a compound into the air when heated to a first temperature.

Provided herein is technology relating to measuring temperature and particularly, but not exclusively, to devices, methods, systems, and kits for doing measuring temperature at high resolution, e.g., in living organisms.

A method and system for the continuous monitoring of animal physiology in laboratory animal cages through the use of miniaturized sensors located throughout the cage and in various fashions including the ability to identify each rodent's digital sensory signature through data fusion and artificial intelligence.

A minimally invasive, microchip-based system which enables continuous long-term recording of subjects (e.g., freely moving rodents) under study including subject behavior, subject brain neurovascular activity, subject heart rate, subject intercranial pressure, subject temperature, and subject head movement is described herein. These systems may also include microchips configured to deliver stimuli such as heat stimuli and measure these various parameters of subjects before, during, and after stimuli. The systems may afford measurement protocols in one or more subjects such as conditioned place/aversion assays and/or pharmacological or medical device testing.

A system for monitoring vital signs of a pet animal comprises an annular band, an accelerometer configured to measure at least one of resting patterns, activity patterns, movement patterns, position patterns relating to, for example the pet animal relieving itself, lameness and scratching, and a non-accelerometer sensor configured to measure at least one of the following non-accelerometer-measured bioparameters of the pet animal: temperature, pulse rate, respiration rate. One or more processors are configured to receive sensor output data and reference data concerning the measured bioparameters of the pet animal or of a population of the pet animal, and determine a suspicion of a specific medical condition by: (i) scoring at least two bioparameters and comparing a cumulative score to a threshold cumulative score or to a threshold cumulative range; or (ii) identifying an abnormal pattern. The processor(s) may send an alert if at least one specific medical condition is suspected.

The field of this invention is classifying animal behaviors. In particular the fields of this invention include using animals in vivariums, such as rodents, particularly mice. In a vivarium cage, animals create ultrasonic vocalizations. In addition, their phenotype changes over time. The vocalizations, a current phenotype, and the cage environments are inputs to a multi-dimensional classifier using clustering algorithms to find multi-dimensional close relationships. Such close relationships may be identified as particular behavior.

A device for detecting and recording animal behavior is provided. The device includes at least one corral that defines a contained field, the base surface of the at least one corral being sensitive to the animal's footprint. The device also includes an image capturing device that cooperates with the base surface to capture both a profile of the animal's full footprint and a profile of the animal's toe print when the animal is standing on its toes. In some embodiments, the device is capable of providing a stimulus to the animal and observing the resulting behavior of the animal via the image capturing device.

Systems and methods described herein provide techniques for automated phenotyping. The systems and methods, in some embodiments, processes video data, identifies body parts, extracts features on a frame-level, and determines subject behavior captured in the video data. The systems and methods may use one or more machine learning models.