A sample collection device for collecting a blood sample of a patient, the sample collection device including a first partially deformable shell and a second at least partially pierceable shell with a pre-packaged vacuum sealed between the first shell and the second shell. The second shell may additionally hold a sample container and an automatic mechanical cutting mechanism including a rotatable cutting blade and an actuator spring, the actuator spring being actuatable by pressing the first shell, thereby releasing and rotating the cutting blade. By pressing the first shell, the pre-packaged vacuum is released to a collection opening of the second shell such that the vacuum effects a suction effect so that blood coming out of the incision created by the rotatable cutting blade leaks into the sample container.

The present disclosure relates to capillary blood sampling. In one aspect, the present disclosure provides a finger lancing device comprising a body having a chamber for receiving a finger and a lancing device comprising a lancing member actuator for actuating a lancing member to lance a finger received in the chamber.

An arrangement for producing a sample of body fluid from a wound opening created in a skin surface at a sampling site includes: a housing, the housing comprising a first opening; a skin interface member disposed in the first opening, the skin interface member comprising an inner member having a second opening, and an outer member at least partially surrounding the inner member and attached to the first opening; and at least one skin-penetration member configured and arranged to project within the second opening. Arrangements having alternatively constructed skin interface members are also described.

A biological fluid separation device that is adapted to receive a multi-component blood sample is disclosed. After collecting the blood sample, the biological fluid separation device is able to separate a plasma portion from a cellular portion. After separation, the biological fluid separation device is able to transfer the plasma portion of the blood sample to a point-of-care testing device. The biological fluid separation device of the present disclosure also provides a closed separation and transfer system that reduces the exposure of a blood sample and provides fast mixing of a blood sample with a sample stabilizer. The biological fluid separation device is engageable with a blood testing device for closed transfer of a portion of the plasma portion from the biological fluid separation device to the blood testing device. The blood testing device is adapted to receive the plasma portion to analyze the blood sample and obtain test results.

An apparatus includes a housing, defining an inner volume, and an actuator mechanism movably disposed therein. The actuator mechanism is configured to be transitioned from a first configuration to a second configuration to define a pre-sample reservoir fluidically couplable to receive a pre-sample volume of bodily-fluid via an inlet port of the housing. The actuator mechanism is movable from a first position to a second position within the housing after the pre-sample reservoir receives the pre-sample volume such that the housing and the actuator mechanism collectively define a sample reservoir to receive a sample volume of bodily-fluid via the inlet port. The outlet port is in fluid communication with the sample reservoir and is configured to be fluidically coupled to an external fluid reservoir after the sample volume is disposed in the sample reservoir to transfer at least a portion of the sample volume into the external fluid reservoir.

Provided is a transdermal microneedle array patch, including: a bottom cover; a top cover; a substrate disposed within the top cover; and a first probe and a second probe disposed between the bottom cover and the top cover and electrically connected the substrate. The first and second probes form an open circuit. While the bottom cover is combined with the top cover to form the transdermal microneedle array patch, the first and second probes form a closed circuit.

In some examples, a diagnostic device includes a reusable part to receive a container of a fluid, the reusable part reusable for a plurality of diagnostic tests. The diagnostic device further includes a disposable part detachably attached to the reusable part and comprising a sample collector to collect a target sample of a living being. The diagnostic device further includes a tester comprising a fluid channel to transport the fluid to combine the fluid and the target sample to form a fluid combination, and to use the fluid combination to diagnose a condition of the target sample.

An apparatus includes an introducer defining an inner volume, a catheter, and a guide member. The having a proximal end portion and a distal end portion, with the catheter defining a lumen extending through the proximal end portion and the distal end portion of the catheter, and with the catheter configured to move between a first position, in which the catheter is disposed within the introducer, and a second position, in which at least the distal end portion of the catheter is distal to the introducer. The guide member is coupled to the introducer, with the guide member defining a lumen. A portion of the catheter is received within the lumen of the guide member when the catheter is in the first position, and the distal end portion of the catheter is distal to the guide member when the catheter is in the second position.

A needle assembly, such as a catheter assembly, having a needle shaft with a needle tip formed from a first rigid material for puncturing a subject. The shaft section, proximal of the needle tip can be formed from a second material different from the first material. The needle tip is attached to the needle shaft to form the needle. The first material can have higher rigidity than the second material and the needle can project through a catheter tube and used in a catheter assembly.

A grinder (220) is provided for use in a method of processing a piece of lateral flow paper, comprising a grinder body (222) defining a grinder storage volume (226) with a top opening for accessing the grinder storage volume and one or more through holes (228) providing a fluid connection through the grinder body into the grinder storage volume, wherein the grinder body further comprises one or more grinding protrusions (229) at an outer surface of the grinder body. Furthermore, a sample container (200) is provided for storing a blood sample provided on a piece of lateral flow paper, comprising a sample container body with a base part, a cylindrical wall extending from the base part and defining a storage volume with an opening for accessing the storage volume, wherein the base part comprises one or more protrusions (209) extending into the storage volume.