The embodiments of the present disclosure provides a device for determining muscle state based on electromyography signal and muscle oxygen saturation. The devices includes: a signal collection module, configured for collecting a human electromyography signal data; a light source detection module, configured for emitting light with different wavelengths; a photosensitive receiver module, configured for receiving light reflected by skin after the light emitted by the light source detection module irradiates the skin; a blood oxygen calculation module, configured for calculating the muscle oxygen saturation based on the light received by the photosensitive receiver module; and a data statistics module, configured for determining the muscle state based on the human electromyography signal data and the muscle oxygen saturation. In this way, an accurate detection of muscle state is realized.

A system for mapping neuromuscular junctions for botulinum neurotoxin (BoNT) injections includes a stimulation electrode and an electromyography (EMG) sensor array including EMG sensors configured to be arranged about a person's face. Each EMG sensor detects muscle activity of a facial muscle of a facial muscle group. An EMG amplifier includes a plurality of input channels. Each input channel receives data of facial muscle activity in the facial muscle group from the EMG sensor array. A computer is in communication with the EMG amplifier. A processor of the computer identifies neuromuscular junctions (NMJs) of the facial muscle group based on the data of facial muscle activity received from the EMG sensor array. The plurality of NMJs are mapped with respect to the at least one facial muscle group of the body of the person. At least one NMJ site for BoNT injection is recommended by the computer.

A mobility augmentation system assists a user's movement by determining a corresponding electrical stimulation for the movement. A wearable stimulation array includes sensors, electrodes, an electrode multiplexer, and a controller that executes the mobility augmentation system. The sensors measure movement data, and the mobility augmentation system applies a movement model to the measured movement data. The model can determine different electrical actuation instructions depending on the movement stimulated. For example, to stimulate a knee flexion, the movement model output enables a first set of the electrodes to operate as cathodes and a second set of electrodes to operate as anodes. To stimulate a knee extension, the first set of electrodes can be enabled to operate as anodes and a third set of electrodes as cathodes. The user can provide feedback of the applied stimulation, which the system can use to retrain the model and optimize the stimulation to the user.

A mobility augmentation system assists a user's movement by determining a corresponding electrical stimulation for the movement. A wearable stimulation array includes sensors, electrodes, an electrode multiplexer, and a controller that executes the mobility augmentation system. The sensors measure movement data, and the mobility augmentation system applies a movement model to the measured movement data. The model can determine different electrical actuation instructions depending on the movement stimulated. For example, to stimulate a knee flexion, the movement model output enables a first set of the electrodes to operate as cathodes and a second set of electrodes to operate as anodes. To stimulate a knee extension, the first set of electrodes can be enabled to operate as anodes and a third set of electrodes as cathodes. The user can provide feedback of the applied stimulation, which the system can use to retrain the model and optimize the stimulation to the user.

A system for reducing and/or eliminating noise in chronic neural recording of low amplitude neural signals from conscious, freely-moving subjects. Triboelectric noise effects are reduced or eliminated using in implant lead with insulating materials with charge affinities separated by 10 nC/J or less. The recording device can include a preamplifier device that uses capacitors with a low-distortion dielectric material.

A system for reducing and/or eliminating noise in chronic neural recording of low amplitude neural signals from conscious, freely-moving subjects. Triboelectric noise effects are reduced or eliminated using in implant lead with insulating materials with charge affinities separated by 10 nC/J or less. The recording device can include a preamplifier device that uses capacitors with a low-distortion dielectric material.

A wearable objective pain measuring device includes a headband configured to be worn by a user on the user's head. The device includes one or more sensors in the headband, including one or more of: a sweep impedance profiling sensor to collect data reflective of activity of corrugator supercilia during a pain session; an electromyography sensor to collect data signals from a brain that reflects pain perception; a photoplethysmogram sensor configured to collect data regarding changes in hear rate and heart rate variability due to pain state; or a galvanic skin response sensor configured to collect data related to changes in sweat gland and skin conductance due to a pain state. The device includes a pain quantification pipeline to objectively quantify pain based on data from the one or more sensors. The device includes an output device configured to output an objective pain quantification based on quantifying pain.

A wearable objective pain measuring device includes a headband configured to be worn by a user on the user's head. The device includes one or more sensors in the headband, including one or more of: a sweep impedance profiling sensor to collect data reflective of activity of corrugator supercilia during a pain session; an electromyography sensor to collect data signals from a brain that reflects pain perception; a photoplethysmogram sensor configured to collect data regarding changes in hear rate and heart rate variability due to pain state; or a galvanic skin response sensor configured to collect data related to changes in sweat gland and skin conductance due to a pain state. The device includes a pain quantification pipeline to objectively quantify pain based on data from the one or more sensors. The device includes an output device configured to output an objective pain quantification based on quantifying pain.

A coupled physiological signal measurement method, a coupled physiological signal measurement system and a graphic user interface are provided. The coupled physiological signal measurement method includes the following steps. An original myoelectric signal is captured. A capacitance value of a skin is obtained. The original myoelectric signal is compensated according to the capacitance value of the skin. The step of compensating the original myoelectric signal according to the capacitance value includes the following steps. The original myoelectric signal is decomposed to obtain several myoelectric sub-signals corresponding to several frequencies, wherein each myoelectric sub-signal has an amplitude variation. The amplitude variations of the myoelectric sub-signals are respectively adjusted according to the capacitance value of the skin. The adjusted myoelectric sub-signals are merged to obtain a compensated myoelectric signal.

A sensing system and method uses a sense electrode arrangement for coupling to a surface of a body such that the sense electrode arrangement and the body (and the spacing between them) define a coupling capacitance. First and second sensing circuits have different transfer functions and generate first and second outputs. These outputs are processed to determine the coupling capacitance. The electrophysiological signal being monitored is also acquired by one or both of the sensing circuits. In this way, the quality of the electrode coupling can be determined in a simple and passive manner.