A wireless, patient-worn, physiological sensor configured to, among other things, help manage a patient that is at risk of forming one or more pressure ulcers is disclosed. According to an embodiment, the sensor includes a base having a top surface and a bottom surface. The sensor also includes a substrate layer including conductive tracks and connection pads, a top side, and a bottom side, where the bottom side of the substrate layer is disposed above the top side of the base. Mounted on the substrate layer are a processor, a data storage device, a wireless transceiver, an accelerometer, and a battery. In use, the sensor senses a patient's motion and wirelessly transmits information indicative of the sensed motion to, for example, a patient monitor. The patient monitor receives, stores, and processes the transmitted information.

A wearable device includes a wearable device main body, a sensor part configured to contact a skin surface of a user of the wearable device, and measure a bio-signal of the user, and a shock absorber that is interposed between the wearable device main body and the sensor part to mechanically connect the wearable device main body and the sensor part, and that is configured to reduce motion transmission between the wearable device main body and the sensor part to permit the wearable device main body to move independently from the sensor part.

Systems are provided for generating data representing electromagnetic states of a heart for medical, scientific, research, and/or engineering purposes. The systems generate the data based on source configurations such as dimensions of, and scar or fibrosis or pro-arrhythmic substrate location within, a heart and a computational model of the electromagnetic output of the heart. The systems may dynamically generate the source configurations to provide representative source configurations that may be found in a population. For each source configuration of the electromagnetic source, the systems run a simulation of the functioning of the heart to generate modeled electromagnetic output (e.g., an electromagnetic mesh for each simulation step with a voltage at each point of the electromagnetic mesh) for that source configuration. The systems may generate a cardiogram for each source configuration from the modeled electromagnetic output of that source configuration for use in predicting the source location of an arrhythmia.

Systems are provided for generating data representing electromagnetic states of a heart for medical, scientific, research, and/or engineering purposes. The systems generate the data based on source configurations such as dimensions of, and scar or fibrosis or pro-arrhythmic substrate location within, a heart and a computational model of the electromagnetic output of the heart. The systems may dynamically generate the source configurations to provide representative source configurations that may be found in a population. For each source configuration of the electromagnetic source, the systems run a simulation of the functioning of the heart to generate modeled electromagnetic output (e.g., an electromagnetic mesh for each simulation step with a voltage at each point of the electromagnetic mesh) for that source configuration. The systems may generate a cardiogram for each source configuration from the modeled electromagnetic output of that source configuration for use in predicting the source location of an arrhythmia.

A PPG PRV device for generating a PRV parameter of a PPG signal (20) as an estimation of a HRV parameter of an ECG signal. The PPG PRV device employs a PPG probe (700) and a PPG PRV controller (710). In operation, the PPG probe (700) generate a PPG signal (20). In response thereto, the PPG PRV controller (710) generates a normalized PPG signal (20′) including a plurality of pulses of the PPG signal (20) designated as normal pulses by the PPG PRV controller (710) and excluding at least one pulse of the PPG signal (20) designated at least one abnormal pulse by the PPG PRV controller (710), wherein the normalized PPG signal (20′) is HRV comparable to the ECG signal. The PPG PRV controller (710) derives the PRV parameter from a HRV measurement of the normalized PPG signal (20′).

A PPG PRV device for generating a PRV parameter of a PPG signal (20) as an estimation of a HRV parameter of an ECG signal. The PPG PRV device employs a PPG probe (700) and a PPG PRV controller (710). In operation, the PPG probe (700) generate a PPG signal (20). In response thereto, the PPG PRV controller (710) generates a normalized PPG signal (20′) including a plurality of pulses of the PPG signal (20) designated as normal pulses by the PPG PRV controller (710) and excluding at least one pulse of the PPG signal (20) designated at least one abnormal pulse by the PPG PRV controller (710), wherein the normalized PPG signal (20′) is HRV comparable to the ECG signal. The PPG PRV controller (710) derives the PRV parameter from a HRV measurement of the normalized PPG signal (20′).

Embodiments disclosed herein relate to devices and methods for monitoring one or more physiological parameters of a subject. In an embodiment, a wearable device comprises a substrate configured to attached to a subject's skin. The substrate comprises a middle portion arranged between two end portions, wherein the middle portion is more flexible than at least one of the end portions. The wearable device also comprises a physiological sensor arranged on the middle portion. The physiological sensor is configured to sense a physiological signal of the subject when the wearable device is attached to the subject's skin. And, the wearable device comprises one or more electrical components arranged on at least one of the end portions, wherein at least one of the one or more electrical components is coupled to the physiological sensor.

Systems and methods can be used to provide an indication of heart function, such as an indication of mechanical function or hemodynamics of the heart, based on electrical data. For example, a method for assessing a function of the heart can include determining a time-based electrical characteristic for a plurality of points distributed across a spatial region of the heart. The plurality of points can be grouped into at least two subsets of points based on at least one of a spatial location for the plurality of points or the time-based electrical characteristics for the plurality of points. An indication of synchrony for the heart can be quantified based on relative analysis of the determined time-based electrical characteristic for each of the at least two subsets of points.

Systems and methods can be used to provide an indication of heart function, such as an indication of mechanical function or hemodynamics of the heart, based on electrical data. For example, a method for assessing a function of the heart can include determining a time-based electrical characteristic for a plurality of points distributed across a spatial region of the heart. The plurality of points can be grouped into at least two subsets of points based on at least one of a spatial location for the plurality of points or the time-based electrical characteristics for the plurality of points. An indication of synchrony for the heart can be quantified based on relative analysis of the determined time-based electrical characteristic for each of the at least two subsets of points.

Systems, methods, and computer-readable media for providing a decision support solution to medical professionals to optimize medical care through data monitoring and feedback treatment are provided herein. In another embodiment, a computer-implemented method for modeling patient outcomes resulting from treatment in a specific medical area includes receiving patient-specific data associated with a patient, determining a plurality of possible patient states under which the patient can be categorized, a current patient state under which the patient can be categorized and determining probabilities of the patient transitioning from any of the possible patient states to every other possible patient state.