An implantable vagus nerve stimulation (VNS) system includes a sensor configured to measure ECG data for a patient, a stimulation subsystem configured to deliver VNS to the patient, and a control system configured to perform a heart rate variability analysis with the ECG data. In some aspects, performing the heart rate variability analysis includes measuring R-R intervals between successive R-waves for the ECG data measured during a stimulation period and a baseline period, plotting each R-R interval against an immediately preceding R-R interval for each of the stimulation period and the baseline period, and determining at least one of a standard deviation from an axis of a line perpendicular to an identity line for each of the stimulation period plot and the baseline period plot or a centroid of each of the stimulation period plot and the baseline period plot.

An imaging system, comprising a shooting operation interface that operates to form an image of a subject, and a processor that has a bio-information acquisition section and a stress determination section, wherein the bio-information acquisition section acquires bio-information of an operator when, during shooting awaiting action where an instant for acquiring still images is awaited, the shooting operation interface is operated, and the stress determination section determines stress conditions that shooting actions place on the operator based on the bio-information that has been acquired using the bio-information acquisition section.

An example device for detecting one or more parameters of a cardiac signal is disclosed herein. The device includes one or more electrodes and sensing circuitry configured to sense a cardiac signal via the one or more electrodes. The device further includes processing circuitry configured to determine an R-wave of the cardiac signal and determine a previous RR interval of the cardiac signal and a current RR interval of the cardiac signal based on the determined R-wave. The processing circuitry is further configured to determine a search window based on one or more of the current RR interval or the previous RR interval, determine a T-wave of the cardiac signal in the search window, and determine a QT interval based on the determined T-wave and the determined R-wave.

An example device for detecting one or more parameters of a cardiac signal is disclosed herein. The device includes one or more electrodes and sensing circuitry configured to sense a cardiac signal via the one or more electrodes. The device further includes processing circuitry configured to determine an R-wave of the cardiac signal and determine a previous RR interval of the cardiac signal and a current RR interval of the cardiac signal based on the determined R-wave. The processing circuitry is further configured to determine a search window based on one or more of the current RR interval or the previous RR interval, determine a T-wave of the cardiac signal in the search window, and determine a QT interval based on the determined T-wave and the determined R-wave.

An implantable neurostimulator-implemented method for managing tachyarrhythmias through vagus nerve stimulation is provided. An implantable neurostimulator, including a pulse generator, is configured to deliver electrical therapeutic stimulation in a manner that results in creation and propagation (in both afferent and efferent directions) of action potentials within neuronal fibers of a patient's cervical vagus nerve. Operating modes of the pulse generator are stored. A maintenance dose of the electrical therapeutic stimulation is delivered to the vagus nerve via the pulse generator to restore cardiac autonomic balance through continuously-cycling, intermittent and periodic electrical pulses. A restorative dose of the electrical therapeutic stimulation is delivered to prevent initiation of or disrupt tachyarrhythmia through periodic electrical pulses delivered at higher intensity than the maintenance dose. The patient's normative physiology is monitored via a physiological sensor, and upon sensing a condition indicative of tachyarrhythmia, is switched to delivering the restorative dose to the vagus nerve.

Means and methods for measuring pain and adapted for calculating the level of nociception during general anesthesia or sedation from data including electroencephalogram (EEG), facial electromyogram (EMG), heart rate variability (HRV) by electrocardiogram (ECG) and plethysmography by impedance cardiography (ICG). In a preferred embodiment of this invention the parameters derived from the EEG, the HRV, the plethysmographic curve and the analgetics concentrations are either combined into one index on a scale from 0 to 100, where a high number is associated with high probability of response to noxious stimuli, while a decreasing index is associated with decreasing probability of response to noxious stimuli. Zero (0) indicates extremely low probability of response to noxious stimuli. In an alternative embodiment, only features from the EEG and ECG will be used or only features from EEG, ECG and ICG, to define the fmal index.

Provided is an electronic device to monitor a user's biological measurements, where a sensor is configured to acquire a first signal from a user, and a diagnostic processor is configured to pre-process the first signal to generate a second signal, segment the second signal to form signal segments, determine at least one event location for each of the signal segments, match adjacent signal segments for feature alignment, and provide a third signal using results of the feature alignment.

In embodiments a WCD system is worn and/or carried by an ambulatory patient. The WCD system analyzes an ECG signal of the patient, to determine whether or not the patient should be given an electric shock to restart their heart. If so, then the WCD system first gives a preliminary alarm to the patient, asking them to prove they are alive if they are. The WCD system further determines whether the ECG signal contains too much High Amplitude (H-A) noise, which can distort the analysis of the ECG signal. If too much H-A noise is detected for a long time, the WCD system may eventually alert the patient about their activity, so that the ECG noise may be abated. The WCD system may even pause the analysis of the ECG signal, so that there will be no preliminary alarms that could be false until the ECG noise is abated.

There is described a method and system for measuring a level of anxiety. Measured data comprising EEG data collected from a parietal (P) EEG electrode is received. A group 8 indicator based on a power, P-power (dt), associated with a delta-theta frequency band, dt, within a delta-theta frequency range is extracted. Based on said group 8 indicator, a level of anxiety, LoA, is determined which is a value indicative of the level of anxiety of the subject.

A system and method for display of subcutaneous cardiac monitoring data are provided. Cutaneous action potentials of a patient and other sensed data associated with the patient are recorded as electrocardiogram (EGC) data over a set time period using a subcutaneous insertable cardiac monitor. A set of R-wave peaks is identified within the ECG data and an R-R interval plot is constructed. A difference between recording times of successive pairs of the R-wave peaks in the set is determined. A heart rate associated with each difference is also determined. The pairs of the R-wave peaks and associated heart rate are plotted as the R-R interval plot. A diagnosis of cardiac disorder is facilitated based on patterns of the plotted pairs of the R-wave peaks, the associated heart rates in the R-R interval plot, and background data based on the other sensed data.