The present invention relates to a flexible pressure sensor using a multi-material 3D-printed microchannel mold, and a method for manufacturing the same. An object of the present invention is to provide a flexible pressure sensor using a multi-material 3D-printed microchannel mold, the flexible pressure sensor being formed by using a conductive liquid and an elastomer, having a microchannel formed therein, and having improved flexibility, sensitivity, and stability in comparison to the related art. Another object of the present invention is to provide a method for manufacturing a flexible pressure sensor using a multi-material 3D-printed microchannel mold, in which the flexible pressure sensor is manufactured by using the microchannel mold including microbumps, the microchannel mold being multi-material 3D-printed by using a sacrificial material and a hard material.

Methods and systems for imaging and analysis are described. Accurate pressure ulcer measurement is critical in assessing the effectiveness of treatment. However, the traditional measuring process is subjective. Each health care provider may measure the same wound differently, especially related to the depth of the wound. Even the same health care provider may obtain inconsistent measurements when measuring the same wound at different times. Also, the measuring process requires frequent contact with the wound, which increases risk of contamination or infection and can be uncomfortable for the patient. The present application describes a new automatic pressure ulcer monitoring system (PrUMS), which uses a tablet connected to a 3D scanner, to provide an objective, consistent, non-contact measurement method. The present disclosure combines color segmentation on 2D images and 3D surface gradients to automatically segment the wound region for advanced wound measurements.

A skin cleanser includes a surface, such as a silicone surface, with at least one textured portion for transmitting vibrational tapping to the skin. The skin cleanser includes at least one oscillating motor for generating the tapping motion to the skin. The textured portion includes touch-points or a wave that transmit the tapping motion to skin in contact with the textured portions. The touch-points may include thicker and thinner formations of the touch-points to provide firmer or softer vibrations to the skin. The touch-points are within about 0.5 to 2.5 mm in diameter. One configuration includes multiple oscillating motors configured to provide different vibration frequencies at around 50-300 Hertz and operable simultaneously.

A wound therapy system includes an instillation fluid canister configured to contain an instillation fluid, a pump fluidly coupled to the instillation fluid canister and operable to deliver the instillation fluid from the instillation fluid canister to a wound, a user interface configured to receive user input indicating one or more geometric attributes of the wound, and a controller electronically coupled to the pump and the user interface. The controller is configured to determine a volume of the wound based on the user input, determine a volume of the instillation fluid to deliver to the wound based on the volume of the wound, and operate the pump to deliver the determined volume of the instillation fluid to the wound.

In some cases, a wound dressing comprises a substantially flexible substrate with a first, wound-facing side supporting a plurality of electronic components and a second side opposite the first side, wherein the substrate comprises a plurality of perforations formed though the substrate and wherein the plurality of perforations comprise walls on the exterior surface of the plurality of perforations, a first substantially stretchable coating applied to the first side of the substrate, and a second substantially stretchable coating applied to second side of the substrate, wherein the walls of the plurality of perforations are at least partially coated with at least one of the coatings.

The apparatus and method for hemostasis that informs the provider as to whether the appropriate magnitude of pressure is being applied to a puncture site on a patient. A visual pulse indicator can visually convey whether or not there is proper blood flow at the puncture site based on the pulsing motion encountered by the visual pulse indicator on the puncture site. The visual pulse indicator can potentially factor in a variety of different input parameters in displaying information that is useful to providers.

Machine learning systems and methods are disclosed for prediction of wound healing, such as for diabetic foot ulcers or other wounds, and for assessment implementations such as segmentation of images into wound regions and non-wound regions. Systems for assessing or predicting wound healing can include a light detection element configured to collect light of at least a first wavelength reflected from a tissue region including a wound, and one or more processors configured to generate an image based on a signal from the light detection element having pixels depicting the tissue region, determine reflectance intensity values for at least a subset of the pixels, determine one or more quantitative features of the subset of the plurality of pixels based on the reflectance intensity values, and generate a predicted or assessed healing parameter associated with the wound over a predetermined time interval.

A wound monitoring and/or therapy system can include a substantially stretchable substrate supporting a plurality of electronic components, including sensors, and a plurality of electronic connections that connect at least some of the electronic components. The electronic components can also include a circuit board supporting at least one controller configured to control at least some of the sensors, the circuit board configured to operate without failure when the substrate is flexed as a result of strain. A calibration track can be positioned on the substrate and connected to a monitoring circuit configured to measure a change in resistance of the calibration track indicative of resistance change of at least some of the plurality of electronic connections. The system can include a controller with a circuit board supporting a plurality of electrical components and an antenna configured to communicate with the substrate, the antenna at least partially enclosing the circuit board.

Medical swabs incorporating a pH indicator in an absorbent crosslinked hydrogel matrix. The medical swabs can provide for visual monitoring of biological pH. The medical swabs can be used to monitor wounds, such as chronic wounds, burn wounds, surgical wounds, etc., as well as other biological fluids. The swabs can be used for early detection of chronic wounds and/or early detection of bacterial infections.

The kit evaluates the patient's skin for penicillin sensitivity. The kit comprises a container, a multi-site skin test system, four preloaded syringes, and a tattoo-type label that is transferable onto the patient's skin. A multi-site skin test applicator is cooperatively engageable with four reservoirs in a fluid tray. The applicator pierces the patient's skin as trace amounts of the allergy test fluids are simultaneously administered. The tattoo-type label is transferable onto the skin of the patient and includes a QR Code. The QR Code includes machine-readable linkage to artificial intelligence for assisting a doctor in interpreting patient test results. The doctor reviews the artificial intelligence analysis and decides either to accept the analysis or modify it. The doctor may also decide to verify negative results with a subcutaneous skin test. The four syringes for the subcutaneous skin tests are preloaded with saline, Pre-Pen, Pen-G, and histamine.