The present disclosure concerns a device for examining a capillary area of the skin of a finger, said device comprising: an optical microscope); —a light source for illuminating the capillary area; —a support comprising a recess for receiving the finger, said recess comprising an opening positioned opposite the microscope; —the microscope being mounted to rotate on the support about a main axis of the finger so as to scan the capillary area from one edge of the finger to the other; —immobilisation means being configured to adjust the dimension of the recess relative to the shape of the finger in order to immobilise the finger in the recess without exerting pressure on the finger. The examination device of the present disclosure is particularly suitable for examining a capillary area of the skin of a finger in order to detect vascular anomalies.

A method (200) for predicting a wellness metric (208, 314, 612) is presented. The method (200) includes maintaining (202) a model which receives as input a set of parameters and provides as output a wellness metric (208, 314, 612). Furthermore, the method (200) includes receiving (204) a set of non-invasive biological parameters (106, 404, 602) of a user (102). In 5 addition, the method (200) includes providing (206) the set of non-invasive biological parameters (106, 404, 602) as the set of parameters to the model to cause the model to generate a wellness metric (208, 314, 612) for the user (102).

System for the optical examination of human nails that has a camera and a power source or a smartphone provided with a connection to these, a converter connected to the smartphone, which converter contains a housing and a measuring probe, the housing contains a microcontroller, the measuring probe contains at least one macro lens and at least one polarising filter, at least two light sources and a polarising filter film in front of some of the light sources arranged in such a way that the axes of polarisation of the polarising filter films and of the polarising filter are rotated by 90 degrees as compared to each other, where due to the various light sources the system is adapted to use various illumination modes and the smartphone is connected to a neural network. Also, a method for the examination of nails for diagnostic purposes with such devices.

A smartphone-based hemoglobin (Hgb) assessment application quantitatively analyzes pallor in patient-sourced photos using image analysis algorithms to enable a noninvasive, accurate quantitative smartphone app for detecting anemia. A user takes a photo of his/her fingernail beds using the app and receives an accurate displayed Hgb level. Since fingernails do not contain melanocytes, the primary source of color of these anatomical features is blood Hgb. At the same time, quality control software minimizes the impact of common fingernail irregularities (e.g. leukonychia and camera flash reflection) on Hgb level measurement. Metadata recorded upon capturing the image is leveraged for determining a users' Hgb level thereby eliminating the need for external equipment. A personalized calibration of image data with measured Hgb levels improves the accuracy of the application.

A treatment system can include a channel generation system configured to expose an infected region of a target tissue with a laser beam traveling along an optical axis and focused at a focal volume located in or adjacent to the target tissue. The laser beam can have a wavelength ranging from about 100 nm to about 400 nm. The laser beam can be configured to generate at least a first channel in the infected region. The treatment system can also include a detection system configured to detect a first radiation generated by one or more of (i) the target tissue, (ii) a fungi coupled to the infected region in the target tissue, and (iii) an adjacent tissue located proximal to the target tissue as a result of interaction with the laser beam. The treatment system can also include a delivery system configured to deposit an active treatment agent in the at least first channel.

A finger insert for use with a nailfold imaging device includes a housing to receive the user's finger and an immersion substance (e.g., immersion oil), and a deformable pad that holds the user's finger in place during imaging, as well as prevent bubble formation in the substance. The housing includes a transparent wall to facilitate imaging of the finger. The transparent wall includes multiple angled portions that prevent or reduce contact between the nailfold and the wall, to ensure sufficient blood flow through the nailfold region for imaging.

A method of determining a likelihood of presence of at least one type of arthritis in a hand of a patient is provided, the method comprising capturing an image of a hand of the patient, processing the hand image to determine at least one first predictive value indicative of presence or absence of arthritis in the hand based on presence or absence of a plurality of identifiable hand features in the hand image, the identifiable hand features including visible physical hand features that are usable to diagnose arthritis in the hand, receiving patient information from the patient, the patient information comprising a plurality of responses to a plurality of respective questions that are relevant to diagnosing arthritis in the hand, and determining a likelihood of presence of at least one type of arthritis in the hand using the at least one first predictive value and the patient information.

A non-invasive and minimally-invasive system and method of detecting iron content in nail and hair samples to diagnose iron deficiency anemia. The system comprises a portable and ultra sensitive magnetometer. A sample of hair or nail is collected from the patient and placed in the magnetometer. The magnetometer is sufficiently sensitive to detect or otherwise indicate the iron content of the sample. Diagnosis can be made based on the detected iron level.

A method includes measuring, using at least one sensor, strain on a nail plate of a subject, wherein the at least one sensor outputs a data stream corresponding to the measuring, communicating the data stream to a receiver, and interpreting, by the receiver, the data stream to determine a parameter of interest of the subject.

Within a first image in a set of images comprising a panoramic view of a scene, a first boundary feature is identified using a model. Within the first boundary feature, a first set of points is selected. Within a second image in the set of images, a second boundary feature is identified using the model. Within the second boundary feature, a second set of points is selected. A set of parameters of a geometrical shape including the first set of points and the second set of points is determined. From the first image and the second image, a panoramic image is formed, the first image placed within the panoramic image according to the position of the first image on the geometrical shape, the second image placed in the panoramic image according to the position of the second image on the geometrical shape.