A wearable biofluid volume and composition system includes a microfluidic flexible fluid capture substrate having a microfluidic channel configured as a sweat collection channel and is configured to be worn on a human body and to collect and analyze biofluid. The microfluidic flexible fluid capture substrate further has a plurality of conductive traces and electrodes. An electronic module is attached to the microfluidic flexible fluid capture substrate and is configured to measure and analyze data from the biofluid collected by the microfluidic flexible fluid capture substrate and to transmit the analyzed data to a smart device.

A test strip for sampling a bodily fluid may include multiple layers of a substrate material, an adhesive between at least some of the multiple layers, and a microfluidic channel formed between at least some of the multiple layers. The test strip may further include multiple electrodes on one of the multiple layers, positioned and partially exposed within the microfluidic channel, an additional material positioned at or near an entrance to the microfluidic channel, to selectively limit the flow of at least one of bubbles or debris into the microfluidic channel, and at least one exit port in at least one of the multiple layers to allow for release of pressure from the test strip. In some embodiments, the test strip is a saliva analysis test strip. In some embodiments, the test strip includes multiple exit ports to prevent blockage of sample flow.

Systems and methods to determine a risk factor related to dehydration and thermal stress of a subject are disclosed. Exemplary implementations may: generate output signals, by one or more sensors worn on a body of a subject, conveying information related to one or more of location of the subject, motion of the subject, temperature of the subject, cardiovascular parameters of the subject; store information related to the subject; obtain the output signals; determine in an ongoing manner, from the output signals, values of a water loss metric that correlates with estimated percentage of bodyweight of the subject lost in water; obtain heat index information for a contextual environment surrounding the subject; determine in an ongoing manner, from the output signals, values of an exertion metric that correlates with exertion of the subject due to work; and determine in an ongoing manner values for an aggregated risk factor of the subject.

A measurement device is provided that has a contact surface that comes into contact with a measurement portion of a living body. The measurement device includes a biosensor disposed on the contact surface and has a detection surface that acquires biological information. Moreover, a suction portion is provided that sucks the living body from one or multiple suction holes provided in the contact surface on a periphery of the detection surface of the biosensor.

A portable apparatus includes an exercise-measurement circuitry that measures exercise-related measurement data related to a user carrying out an exercise, a communication circuitry configured to provide the portable apparatus with wireless communication capability, and a processing circuitry configured to a perform operations. The operations include receiving the exercise-related measurement data from the exercise-measurement circuitry, receiving configuration data from an external user interface apparatus over a bidirectional wireless communication connection established through the communication circuitry and capable of transferring payload data to both directions, processing the exercise-related measurement data according to the received exercise-related parameters in order to obtain advanced exercise-related data, and communicating the advanced exercise-related measurement data to the user interface apparatus over the bidirectional wireless communication connection.

A biomarker diagnostic system includes a sensor to collect a sweat sample from a biological subject; a processor operatively connected to the sensor, wherein the processor is configured to perform metabolic and proteomic profiling of biomarkers in the sweat sample. The metabolic and proteomic profile is compared to a predetermined profile of the biomarkers and to determine a physiological status of the biomarkers. The system further includes a feedback unit operatively coupled to the sensor and the processor and configured to output physiological performance data based on the physiological status.

Embodiments herein relate to ear-wearable systems and devices for detecting heat stress and related methods. In an embodiment, an ear-wearable heat stress risk assessment system is included having a control circuit, a microphone, and a sensor package. The system is configured to process signals of one or more sensors of the sensor package and/or the microphone, detect dehydration symptoms, environmental conditions, and activity levels of a device wearer based on the processed signals, and determine a heat stress risk level based on detected dehydration symptoms, environmental conditions, and activity levels of the device wearer. Other embodiments are also included herein.

A method for using saliva to measure at least one substance or physiological parameter of a human or animal subject may involve inserting a first end of a sensor into a handheld saliva testing device. The method may also involve receiving saliva from the subject on a second end of the sensor, moving the saliva from the second end of the sensor to the first end, and processing the saliva with the handheld saliva testing device to provide initial saliva data related to the at least one substance or physiological parameter of the subject. In some embodiments, the sensor remains inserted in the handheld device while the subject deposits saliva on the opposite, free end of the sensor.

A tissue hydration monitor and method includes a sensor module having a plurality of LEDs positioned to emit a plurality of different wavelengths of light toward the user's skin and a detector that detects light transmitted and reflected through the user's skin to generate signals corresponding to an intensity of detected light at each of the different wavelengths. A processor/controller module generates a baseline hydration level based on the received signals, calculates a relative hydration level, and generates an output indicative of relative hydration personalized to the user. The housing is secured against the user's skin by an adhesive patch or a strap.

Methods and apparatus for detecting body vital signs through the use of a Bioelectric Impedance Spectroscopy (BIS), either by (a) direct contact with the person (such as through one or more of their fingers) or (b) measurement of reflections from a field projected into the person's body. The techniques may be implemented using the projected capacitive touch array in a device such as the screen of a smartphone or tablet computer, or the touchpad of a laptop computer.