Gamma cameras may be used to obtain two-dimensional images of an emitting object, of which the most common form is the “Anger-type” gamma camera. The primary components in a conventional Anger-type gamma camera include, but are not limited to: a plurality of photo-multiplier tubes, a scintillator material, and a collimator. The disclosed invention claims a novel use of a gamma camera which eliminates the collimator. The new method is a method of forming an initial image from the incident radiation, which does not depend on any mechanical or other means of restricting the incident radiation to be passed on to a position-sensitive radiation detector. This method then uses mathematical deconvolution to produce an image of the object without the need for a collimator and without reliance on a pre-existing image.

An imaging system is provided that includes a gantry, at least five detector units mounted to the gantry, a corresponding collimator for each of the detector units, at least one processing unit, and a controller. Each collimator has septa defining plural bores for each pixel of at least some of a plurality of pixels of the detector unit. A corresponding interior septum of the collimator is disposed above an internal portion of a corresponding pixel of the at least some of the plurality of pixels. The at least one processing unit is configured to obtain object information corresponding to the object to be imaged. The controller is configured to control an independent rotational movement of each the detector units used to acquire scanning information by detecting emissions from the object, wherein the controller rotates each of the detector units at a corresponding sweep rate.

A diagnostic contrast composition includes a carrier fluid and a non-decaying gas-evolving fluid incorporated in the carrier fluid. The gas-evolving fluid has a vapor pressure sufficient to evolve the gas from a circulatory system within a lung of a patient. The gas-evolving fluid is a composition containing a sufficient quantity of atoms with an atomic number higher than 8 to provide an increased absorption sufficient to increase a Hounsfield Unit measurement in an image in a CT imaging system. The gas-evolving fluid is selected from the group consisting of xenon gas, krypton gas, sulfur hexafluoride, a perfluorocarbon, a brominated perfluorocarbon, and combinations thereof. The carrier fluid is selected from the group consisting of water, saline, saline comprising one or more blood proteins, and saline comprising dissolved lipids.

A method is for providing respiratory information. In an embodiment, the method includes receiving imaging data relating to a lung; calculating a perfusion fraction for each respective region of a set of regions of the lung, based on the imaging data; calculating a respective ventilation value for each respective region of the set of regions of the lung based on the imaging data; calculating a weighted average of respective ventilation values across all respective regions of the set of regions of the lung, wherein for each respective region of the set of regions of the lung, the respective ventilation value of the respective region is weighted with the perfusion fraction of the respective region; generating the respiratory information based on the weighted average of the respective ventilation values; and providing the respiratory information.

A collimator for a detector is disclosed. The collimator comprises: a bottom plate provided with imaging through holes distributed in an array, each of the imaging through holes comprising a first hole segment and a second hole segment, the transverse size of the first hole segment gradually decreasing in a direction from a free end to the second hole segment, and the transverse size of the second hole segment gradually decreasing in a direction from the free end to the first hole segment; a shielding case formed on the bottom plate; and a top plate disposed in the shielding case and closing at least a part of an opening of the shielding case, the top plate being provided with shielding through holes distributed in an array, and the imaging through holes being in one-to-one correspondence with the shielding through holes.

The present disclosure relates to a method for scanning a patient in an imaging system. The imaging system may include one or more cameras directed at the patient. The method may include obtaining a position of each of the camera(s) relative to the imaging system. The method may also include obtain image data of the patient captured by the camera(s), wherein the image data may correspond to a first view with respect to the patient. The method may further include generating projection image data of the patient based on the image data and the position of each of the camera(s) relative to the imaging system, wherein the projection image data may correspond to a second view with respect to the patient different from the first view. The method may further include generating control information for scanning the patient based on the projection image data of the patient.

Emission imaging data are reconstructed to generate a low dose reconstructed image. Standardized uptake value (SUV) conversion (30) is applied to convert the low dose reconstructed image to a low dose SUV image. A neural network (46, 48) is applied to the low dose SUV image to generate an estimated full dose SUV image. Prior to applying the neural network the low dose reconstructed image or the low dose SUV image is filtered using a low pass filter (32). The neural network is trained on a set of training low dose SUV images and corresponding training full dose SUV images to transform the training low dose SUV images to match the corresponding training full dose SUV images, using a loss function having a mean square error loss component (34) and a loss component (36) that penalizes loss of image texture and/or a loss component (38) that promotes edge preservation.

Gamma ray detection system comprising a detection module assembly including at least two detection modules configured for positron emission tomography (PET) scanning of a target zone, each detection module comprising a plurality of stacked scintillator plates each having a major surface oriented to generally face the target zone and lateral minor surfaces defining edges of the scintillator plates, a plurality of photon sensors being mounted against said edges layer photon sensor 18a configured to detect a scintillation event in the scintillator plate from a gamma ray incident on the major surface. The gamma ray detection system is further configured to function as a Compton camera, at least one scintillator plate that is not the scintillator plate closest to the target zone being configured as an absorber scintillator plate for said Compton camera.

Methods and devices for producing cavitation in tissue are provided. Methods and devices are also provided for surgical navigation, including defining a target treatment zone and navigating a focus of a therapy transducer to the target treatment zone. Embodiments are provided for co-registering a plurality of surgical imaging and navigation systems. Systems for performing Histotripsy therapy are also discussed.

The present disclosure provides systems and methods for hybrid imaging. The systems and methods may obtain a first magnetic resonance (MR) image of a target object. The first MR image may be acquired by a magnetic resonance imaging (MRI) device using a first imaging sequence. The systems and methods may also obtain a second MR image of the target object. The second MR image may be acquired by the MRI device using a second imaging sequence. The second MR image may correspond to a target respiratory phase of the target object. The systems and methods may also obtain a target emission computed tomography ECT) image of the target object. The target ECT image may correspond to the target respiratory phase. The systems and methods may further fuse, based on the second MR image, the first MR image and the target ECT image.