An integrated microtomography and optical imaging system includes a rotating table that supports an imaging object, an optical stage, and separate optical and microtomography imaging systems. The table rotates the imaging object about a vertical axis running therethrough to a plurality of different rotational positions during a combined microtomography and optical imaging process. The optical stage can be a trans-illumination, epi-illumination or bioluminescent stage. The optical imaging system includes a camera positioned vertically above the imaging object. The microtomography system includes an x-ray source positioned horizontally with respect to the imaging object. Optical and x-ray images are both obtained while the imaging object remains in place on the rotating table. The stage and table are included within an imaging chamber, and all components are included within a portable cabinet. Multiple imaging objects can be imaged simultaneously, and side mirrors can provide side views of the object to the overhead camera.

Methods and systems for navigating to a target through a patient's bronchial tree are disclosed including a bronchoscope, a probe insertable into a working channel of the bronchoscope and including a location sensor, and a workstation in operative communication with the probe and the bronchoscope, the workstation including a user interface that guides a user through a navigation plan and is configured to present a central navigation view including a plurality of views configured for assisting the user in navigating the bronchoscope through central airways of the patient's bronchial tree toward the target, a peripheral navigation view including a plurality of views configured for assisting the user in navigating the probe through peripheral airways of the patient's bronchial tree to the target, and a target alignment view including a plurality of views configured for assisting the user in aligning a distal tip of the probe with the target.

A system and method for tracking completeness of co-registered medical image data is disclosed herein. The system and method tracks the position of an anatomical reference marker positionable on a patient and an ultrasound probe during an imaging session and co-registers medical images based on positional data received from the anatomical reference marker and the ultrasound probe. Using the co-registered image data, the system and method generates a surface contour of a region of interest (ROI) of the patient, such as a breast. The surface contour is defined to represent an interface between a chest wall structure and tissue of the ROI in a plurality of co-registered medical images. A completeness map of the image data within the defined surface contour during the imaging session is generated and overlaid on a graphic representation of the ROI.

The invention refers to an apparatus for monitoring a subject (121) during an imaging procedure, e.g. CT-imaging The apparatus (110) comprises a monitoring image providing unit (111) providing a first monitoring image and a second monitoring image acquired at different support positions, a monitoring position providing unit (112) providing a first monitoring position of a region of interest in the first monitoring image, a support position providing unit (113) providing support position data of the support positions, a position map providing unit (114) providing a position map mapping calibration support positions to calibration monitoring positions, and a region of interest position determination unit (115) determining a position of the region of interest in the second monitoring image based on the first monitoring position, the support position data, and the position map. This allows to determine the position of the region of interest accurately and with low computational effort.

A method comprises: applying a first trained function to first input data to generate first output data, the first output data including first key elements; receiving second input data, the second input data being an X-ray image of an examination region acquired using a first collimation region; applying a second trained function to the second input data to generate second output data, the second output data including second key elements; receiving third input data in response to an incomplete set of second key elements, the third input data including the second key elements and an X-ray image of the examination region acquired using the first collimation region; applying a third trained function to the third input data to generate third output data, the third output data including an estimated third key element to complete the set of second key elements; and providing a complete set of second key elements.

The present disclosure provides a system and method for motion field generation and image correction. The method may include obtaining a plurality of first sets of magnetic resonance (MR) image data of an object generated based on a plurality of first sets of imaging sequences. The method may include obtaining a motion curve of the object. The method may include obtaining position emission tomography (PET) image data of the object generated in a scanning time period. The method may include generating one or more target motion fields corresponding to the scanning time period based on the plurality of first sets of MR image data and the motion curve. The method may include generating one or more corrected PET images by correcting, based on the one or more target motion fields, the PET image data.

Systems and methods for improving soft tissue contrast, characterizing tissue, classifying phenotype, stratifying risk, and performing multi-scale modeling aided by multiple energy or contrast excitation and evaluation are provided. The systems and methods can include single and multi-phase acquisitions and broad and local spectrum imaging to assess atherosclerotic plaque tissues in the vessel wall and perivascular space.

An image alignment apparatus includes at least one processor, and the processor derives, for each of first and second three-dimensional images each including a plurality of tomographic images and a common structure, first and second three-dimensional coordinate information that define an end part of the structure in a direction intersecting the tomographic image. The processor aligns the first three-dimensional image and the second three-dimensional image by using the first and second three-dimensional coordinate information to align the common structure included in each of the first three-dimensional image and the second three-dimensional image at least in the direction intersecting the tomographic image.

Methods are provided for dynamically visualizing information in image data of an object of interest of a patient, which include an offline phase and an online phase. In the offline phase, first image data of the object of interest acquired with a contrast agent is obtained with an interventional device is present in the first image data. The first image data is used to generate a plurality of roadmaps of the object of interest. A plurality of reference locations of the device in the first image data is determined, wherein the plurality of reference locations correspond to the plurality of roadmaps. In the online phase, live image data of the object of interest acquired without a contrast agent is obtained with the device present in the live image data, and a roadmap is selected from the plurality of roadmaps. A location of the device in the live image data is determined. The reference location of the device corresponding to the selected roadmap and the location of the device in the live image data is used to transform the selected roadmap to generate a dynamic roadmap of the object of interest. A visual representation of the dynamic roadmap is overlaid on the live image data for display. In embodiments, the first image data of the offline phase covers different of phases of the cardiac cycle of the patient, and the plurality of roadmaps generated in the offline phase covers the different phases of the patient's cardiac cycle. Related systems and program storage devices are also described and claimed.

A medical information processing system in an embodiment includes processing circuitry. The processing circuitry acquires an ultrasound image including an observation target and having additional information, positional information indicating a position of an ultrasound probe in a subject at time of collection of the ultrasound image, and a reference image obtained by taking an image of a region including the observation target at a time point other than the time of collection. The processing circuitry generates, based on the positional information, correspondence information in which the ultrasound image and the reference image are associated with each other. The processing circuitry causes an output unit to output the generated correspondence information.