An implantable screw for maintaining horizontal and/or vertical space during bone grafting procedures. The screw includes a head having a top surface configured to engage a dental membrane, a shaft, and a tip. The shaft is at least partially threaded to engage bone. The dental membrane and the screw provide space for bone growth material during bone grafting.

Provided herein are biomimetic osteochondral implants that are generally useful for the at least partial resurfacing of damaged cartilage within a joint. The implants are constructed to have a modular, layered structure in which the physical properties (e.g., stiffness and lubricity) or dimensions of each layer can be adjusted (e.g., by using the appropriate material and controlling the thickness thereof) based on the anatomy to be replaced. For example, the material and or thicknesses of the layers can be selected to approximate the physical properties and/or dimensions of cartilage (and, optionally, chondral and subchondral bone). Also provided herein are methods of treatment involving the use of said biomimetic osteochondral implants to repair an osteochondral defect in a joint.

Provided herein are scaffold biomaterials including a decellularized plant or fungal tissue from which cellular materials and nucleic acids of the tissue are removed, the decellularized plant or fungal tissue having a 3-dimensional porous structure; wherein the decellularized plant or fungal tissue may optionally be at least partially coated or mineralized, wherein the scaffold biomaterial may optionally further include a protein-based hydrogel and/or a polysaccharide-based hydrogel, or both. Also provided herein are methods and uses of such scaffold biomaterials, including methods of manufacture as well as methods and uses for bone tissue engineering, for example.

The invention relates to a bone implant (1) for correcting an incorrect position of a bone, the bone implant (1) having a first portion (2) for attachment to a first bone portion (3) and a second portion (4) for attachment to a second bone portion (5), the bone implant (1) being prepared so that, when fixed to the bone, it orients the first bone portion (3) and the second bone portion (5) with respect to one another and keeps said portions at a distance from one another, the bone implant (1) having such a geometry and being adapted so as to force a predetermined orientation of the second bone portion (5) relative to the first bone portion (3). The invention also relates to a method for producing such a bone implant (1).

A system or method for bioprinting bone graft provides obtaining an image of the patient's oral facial area, and viewed with the image viewing software. A restoratively driven dental implant treatment plan is created to restore the patient's missing dentition. The restoratively driven treatment plan is created. A physical exam, review of a patient's desires and expectations, review of imaging, acquisition and review of patient photographs and intraoral digital impressions. The imaging and digital impressions are aligned, via software to create a virtual representation. The anticipated final implant retained dentures, unitary implant crowns, or implant bridges, are planned to provide optimal esthetic and functional results. Dental implants are then planned for prosthetic anchors. Bone deficiencies are evaluated and if areas of boney deficiency are present, a patient specific bone graft is designed to restore said deficient areas. Once designed, it may be printed via additive manufacturing.

Exemplary cutting and alignment guide assemblies for use in microsurgical, plastic surgical, otolaryngological, maxillofacial, orthopedic, dental, or other surgical procedures include a first section configured to engage a first bone graft section, a second section configured to engage a second bone graft section, a first fixation mechanism configured to couple the first section with the first bone graft section, and a second fixation mechanism configured to couple the second section with the second bone graft section. The first section and the second section can be coupled via a hinge mechanism. Neo-mandible assemblies for implantation at a native mandibular defect of a patient can include a cutting and alignment guide coupled with one or more bone graft sections. In some cases, bone graft sections include bone segments from a fibula of the patient.

The present invention provides a method of bone regeneration for repairing a bone defect in a subject in need thereof. The method comprises the use of blood aspirate of the mandible bone marrow with the use of xenogen bone support.

A prosthesis for at least a portion of a bone, in particular a bone or portion thereof to which, in the natural condition, a tendon of a muscle is attached, wherein the prosthesis is manufactured of a metal or an alloy thereof and is provided with at least one area situated in the surface of the prosthesis that faces outward once the prosthesis has been placed in the body, the area being formed by a layer provided with open spaces that are connected to each other, wherein the open spaces are dimensioned for allowing the growth of bone tissue therein.

Described are fibula malleolus caps and surgery devices with fibula malleolus caps. The fibula malleolus caps may be patient-specific fibula malleolus caps. The devices with patient-specific fibula malleolus caps overcome the sliding and rotational errors during fibula flap harvesting. A comparative clinical study demonstrates that the fibula malleolus cap enhances the accuracy of fibula flap harvesting, leading to accurate location and angulation of simultaneous dental implants.

The invention relates to an implant for covering bone defects in the jaw region, which comprises a magnesium film.