A knee prosthesis comprises a unicondylar knee prosthesis having a unicondylar insert platform and a tibial base attached to a bottom side of the unicondylar insert platform. The unicondylar insert platform has a uniform stiffness gradient (e.g., a density or porosity gradient), whereas the tibial base has a non-uniform stiffness gradient (e.g., a density or porosity gradient) when the tibial base is viewed from a cross-sectional coronal plan. For example, the tibial base may have an area of greatest stiffness or density centrally located relative to an inboard and outboard side of the tibial base. Alternatively, the area of greatest stiffness or density may be located toward the outboard side. Additionally, the tibial base may include density wells having increased density relative to the surrounding area of the tibial base.

An implant for repairing an articular cartilage defect site including an implant fixation portion with an upper segment and at least one bone interfacing segment and a top articulating portion with an articulating surface and an engagement surface. The upper segment includes a supporting plate with a first locking mechanism segment. The engagement surface includes a second locking mechanism segment. The first locking mechanism segment with at least two channels is structured to couple to the second locking mechanism segment with at least two protrusions. The at least one bone interfacing segment structured for insertion into the articular cartilage defect site. An implant including an implant fixation portion, a top articulating portion, and a locking mechanism with a first locking segment coupled to the upper segment and a second locking segment coupled to the at least one engagement surface and structured to couple to the first locking segment.

Provided herein are biomimetic osteochondral implants that are generally useful for the at least partial resurfacing of damaged cartilage within a joint. The implants are constructed to have a modular, layered structure in which the physical properties (e.g., stiffness and lubricity) or dimensions of each layer can be adjusted (e.g., by using the appropriate material and controlling the thickness thereof) based on the anatomy to be replaced. For example, the material and or thicknesses of the layers can be selected to approximate the physical properties and/or dimensions of cartilage (and, optionally, chondral and subchondral bone). Also provided herein are methods of treatment involving the use of said biomimetic osteochondral implants to repair an osteochondral defect in a joint.

A personalized intervertebral disc replacement for a subject includes a first element adapted to contact a first vertebra in the spine of the subject, a second element adapted to contact a second vertebra adjacent to the first vertebra in the spine of the subject, and a set of links coupling the first and second elements, the links arranged as a passive parallel mechanism, each of the links having a predetermined stiffness and length, and at least some of the links being oriented obliquely to a direction perpendicular to either of the first and second elements.

The present disclosure relates to an orthopedic implant, wherein the implant is a 3D printed part and comprises at least one first portion and at least one second portion, the first portion forming a support structure and the second portion being at least partially made of a biodegradable material.

The present disclosure further relates to a method of manufacturing an orthopedic implant.

The embodiments provide various interbody fusion spacers, or cages, for insertion between adjacent vertebrae. These intervertebral cages can restore and maintain intervertebral height of the spinal segment to be treated, and stabilize the spine by restoring sagittal balance and alignment. The cages may have a first, insertion configuration characterized by a reduced size at each of their insertion ends to facilitate insertion through a narrow access passage and into the intervertebral space. The cages may be expanded to a second, expanded size once implanted. In their second configuration, the cages are able to maintain the proper disc height and stabilize the spine by restoring sagittal balance and alignment. The intervertebral cages are configured to be able to adjust the angle of lordosis, and can accommodate larger lodortic angles in their second, expanded configuration. Further, these cages may promote fusion to further enhance spine stability by immobilizing the adjacent vertebral bodies.

The present disclosure provides an apparatus comprising a wire having a first end and a second end opposite the first end. A first portion of the wire including the first end comprises a malleable region that is configured to remain deformed after bending, and a second portion of the wire including the second end comprises a superelastic region that is configured to return to a straight configuration after bending.

Disclosed is a method for forming an orthopaedic implant. The method comprises determining one or more parameters of a bone, of a subject, to which the implant is to be attached, and calculating specifications based on parameters. That calculation includes calculating a mechanical property relating to elasticity of the implant, a length of the implant, and positions of two or more fixation locations by which to fix the implant to the bone. The method further comprises forming the implant based on the specifications, wherein each fixation location comprises a longitudinal axis through the implant, and calculating specifications comprises calculating a trajectory for the longitudinal axis of the respective fixation location.

A stent for insertion into a vessel of a patient includes an inner tube comprising a positive Poisson's ratio (PPR) material and defining a lumen extending along a longitudinal axis of the stent; and an outer tube comprising a negative Poisson's ratio (NPR) foam material and disposed around an entirety of the inner tube, the outer tube extending along the longitudinal axis of the stent. The stent is configured to exhibit an auxetic behavior in response to a deformation of the stent. An outer surface of the second portion is configured to apply a pressure to an inner surface of the vessel when the stent is implanted into the vessel and the deformation is removed.

Methods and apparatus are disclosed for distracting tissue. The devices and methods may include insertion of first and second elongated members into the space between two tissue layers, with an augmenting elongated member at least partially inserted therebetween to form a distraction device between the tissues to be distracted. At least one of the first and second elongated members may be formed of a flexible core member with a plurality of rigid veneer members spaced along the length of the core member. At least one of the elongated members may include a shaping member that automatically moves from a generally linear configuration to a generally less linear configuration. A deployment catheter may include a deformable distal end to allow augmentation of the tissue distraction device during implantation. An injection aid may be provided for introducing a filler material into an interior defined by a deployed tissue distraction device.