A temperature therapy system and a method for temperature control for such a temperature therapy system are disclosed. According to one embodiment, a temperature therapy system has a retention mechanism and a plurality of temperature modulation systems attached to the retention mechanism, wherein each of the plurality of temperature modulation systems comprises a thermoelectric cooler. The wearable personal temperature therapy system may have a plurality of temperature sensors and a plurality of conductive flags, wherein each of the plurality of conductive flags is adhered to a respective thermoelectric cooler and a respective temperature sensor. The wearable personal temperature therapy system may have a control module electrically coupled to each of the plurality of temperature modulation systems and each of the plurality of temperature sensors, wherein each of the temperature modulation systems is controlled based on a control voltage applied to the thermoelectric cooler of the respective temperature modulation system.

Apparatus and methods related to an underbody support for supporting a body of a being, such as during surgery to prevent contact pressure injuries. In certain embodiments, the underbody support may include one or more inflatable chambers enclosing a volume. At least one of the inflatable chambers may include one or more compression sensitive switches for monitoring the volume of the inflatable chamber, and the one or more compression sensitive switches may be located within the inflatable chamber. In some embodiments the one or more compression sensitive switches are sized to close when the said inflatable chamber is deflated to a desired residual volume.

Personal thermal stability control herein provides for personalized temperature regulation dependent upon biometric sensor feedback, sleep stage, and so on, particularly for sleeping users, predicting and preemptively responding to fluctuations indicative of thermal stability, resulting from such things as transitions between sleep stages, hot flashes, night sweats, and general thermal instability. Specifically, in one embodiment, a system herein may comprise: an on-demand cooling system; one or more biometric sensors configured to monitor one or more corresponding indicators of thermal stability of a user; and a controller configured to: a) receive the one or more corresponding indicators of thermal stability of the user; b) predict an onset of a thermal instability of the user based on the one or more corresponding indicators of thermal stability of the user; and c) activate the on-demand cooling system to counteract the predicted onset of a thermal instability of the user.

Methods of treating tumors by administering compounds to a patient are provided. Compounds such as pro drugs, e.g., 5-aminolevulinic acid (5-ALA), may be administered to the patient orally, by injection, intravenously, or topically, which then accumulate preferentially as compounds such as protoporphyrin IX (PpIX) in tumor cells. After such accumulation, compounds such as PpIX are then activated in various aspects to treat tumors cells, thereby treating cancer. Cancers such as glioblastoma may be treated.

A patient temperature control system for automated temperature control according to a programmed protocol. In one aspect, at least one programmed protocol may be established for each of a plurality of patient thermal therapy phases. In turn, the temperature of a thermal exchange medium may be controlled upon the programmed protocol during each of the phases. A plurality of programmed protocols may be established, wherein a selected protocol may be utilized for automated temperature control during patient thermal therapy. The protocol may include a target patient temperature and/or a set duration for one or more of the phase of thermal therapy. The protocol may be user-definable and modifiable during therapy. In a multiphase configuration, automatic termination and initiation of successive phases may be selectively established by a user, based on target patient temperature data and/or set duration data on a phase-specific basis.

Systems and methods include a heat transfer body with opposing major surfaces formed from a thermally conductive substrate in intimate thermal interaction with an alumina exterior surface that extends across the major surfaces of the body. In an illustrative example, the heat source may be a substantially planar, silicone-based heater source (P-SBHS). The heat transfer body may be configured to thermally interact, for example, heat from a heat source proximate a first of the major surfaces to a second of the major surfaces. A temperature sensor module may be located, for example, proximate to the first major surface such that a temperature sensor thermally interacts with the first major surface. The temperature sensor module may, for example, insulate the temperature sensor from the P-SBHS.

A pressure injuries therapeutic support surface is illustrated. The surface comprises an integrated system designed for a concurrent physical and psychoneuroimmunological approach over a user, wherein the system comprises one or a plurality of independent fluid-filled main chambers, made of waterproof, flexible, extendable, and elastic material and at least two accessory chambers connected to each main chamber with at least with two free-flow conduits. The system is managed through a powered mechatronic array with its own hardware and software based on microcontrollers for the simultaneous operation of specific multidisciplinary devices.

An equine thermal therapy overleg device that encircles a pastern of a subject horse and provides thermal therapy to the subject horse. The may include a pastern dual layer component, a distal phalanx cover and a distal phalanx slipper. The arrangement of the pastern dual layer component, a distal phalanx cover and a distal phalanx slipper allow for free movement of the subject horse and for a thermal fluid to contain ice and prevent the ice from becoming lodged around the subject horse hoof.

A method and system in accordance with a particular embodiments of the technology includes applying a substance onto skin of a human subject. The applied substance can include a freezing point depressant and a liposome, an oil-in-water emulsion, a water-in-oil emulsion, or an oil-in-oil emulsion and can be configured to protect or target tissue. The substance and a surface of the skin can be cooled using the applicator to treat acne and other skin conditions.

A heat exchanger is disclosed for causing cryolysis of adipose tissue of a human tongue. The heat exchanger includes a body having cooling channels for circulating fluids therein. The body forms a contact surface that contacts a portion of the dorsal surface of the tongue and a portion of the base of the tongue. The heat exchanger includes a pair of side walls extending from the body and forming a pair of side contact surfaces that are dimensioned so that they contact the dorsal and lateral surfaces of the tongue in a manner so as to constrict the tongue when the contact surface is in contact with the tongue. A method of treatment for apnea using the heat exchanger and/or administering a chemical adipolysis formulation/vasoconstriction agent is also disclosed.