Patent classifications
A61K31/545
Compositions containing exosome carrying NF-κB inhibitors and methods of using thereof
The present invention is related to compositions containing extracellular vesicles (exosomes) and methods of using the same for increasing lifespan of fetus, viability of fetus, or viability of newborn, for treating inflammation in uterus and/or fetus, for delaying preterm birth, or for treating a condition related to inflammation in uterus and/or fetus, wherein the extracellular vesicles comprising a nuclear factor kappa beta (NF-κB) inhibitor and a photo-specific binding protein.
Compositions containing exosome carrying NF-κB inhibitors and methods of using thereof
The present invention is related to compositions containing extracellular vesicles (exosomes) and methods of using the same for increasing lifespan of fetus, viability of fetus, or viability of newborn, for treating inflammation in uterus and/or fetus, for delaying preterm birth, or for treating a condition related to inflammation in uterus and/or fetus, wherein the extracellular vesicles comprising a nuclear factor kappa beta (NF-κB) inhibitor and a photo-specific binding protein.
Combination of bactericidal agent with a lysosomotropic alkalinising agent for the treatment of a bacterial infection
The present invention relates to the field of medicine, specifically the field of bacterial infection and treatment thereof.
Combination of bactericidal agent with a lysosomotropic alkalinising agent for the treatment of a bacterial infection
The present invention relates to the field of medicine, specifically the field of bacterial infection and treatment thereof.
Methods of treating bacterial infections
Methods for treating a bacterial infections, including drug-resistant bacterial infections, of a patient are described. The methods may include applying a non-thermal plasma and a liquid simultaneously to infected tissue of the patient, the liquid comprising at least one antibiotic and/or antiseptic and a penetration enhancing agent; wherein the non-thermal plasma has a frequency between 200 kHz and 600 kHz.
Methods of treating bacterial infections
Methods for treating a bacterial infections, including drug-resistant bacterial infections, of a patient are described. The methods may include applying a non-thermal plasma and a liquid simultaneously to infected tissue of the patient, the liquid comprising at least one antibiotic and/or antiseptic and a penetration enhancing agent; wherein the non-thermal plasma has a frequency between 200 kHz and 600 kHz.
ANTI-INFLAMMATORY PHARMACEUTICAL COMPOSITION COMPRISING PROBIOTICS AND ANTIBIOTICS, AND METHOD USING SAME
This application relates to a pharmaceutical composition for anti-inflammation, including a probiotic and an antibiotic, and a method of preventing or treating inflammation by using the same. In one aspect, the method includes locally administrating a probiotic and an antibiotic to an inflamed area of a subject.
ANTI-INFLAMMATORY PHARMACEUTICAL COMPOSITION COMPRISING PROBIOTICS AND ANTIBIOTICS, AND METHOD USING SAME
This application relates to a pharmaceutical composition for anti-inflammation, including a probiotic and an antibiotic, and a method of preventing or treating inflammation by using the same. In one aspect, the method includes locally administrating a probiotic and an antibiotic to an inflamed area of a subject.
NOVEL SUBTITUTED SULFONYLUREA AND SULFOXIMINEUREA DERIVATIVES
The present invention relates to novel compounds of the general formula (I) their pharmaceutically acceptable salts, pharmaceutically acceptable solvates, enantiomers, diastereomers and polymorphs. The invention also relates to processes for the preparation of the compounds of invention, pharmaceutical compositions containing the compounds and their use as the compounds of the invention belong to the family of NOD-like receptor family (NLR) protein NLRP3 modulators. The present invention thus relates to novel NLRP3 modulators as well as to the use of the novel inhibitor compounds in the treatment of diseases or conditions in which interleukin 1β activity is implicated.
##STR00001##
NOVEL SUBTITUTED SULFONYLUREA AND SULFOXIMINEUREA DERIVATIVES
The present invention relates to novel compounds of the general formula (I) their pharmaceutically acceptable salts, pharmaceutically acceptable solvates, enantiomers, diastereomers and polymorphs. The invention also relates to processes for the preparation of the compounds of invention, pharmaceutical compositions containing the compounds and their use as the compounds of the invention belong to the family of NOD-like receptor family (NLR) protein NLRP3 modulators. The present invention thus relates to novel NLRP3 modulators as well as to the use of the novel inhibitor compounds in the treatment of diseases or conditions in which interleukin 1β activity is implicated.
##STR00001##