A composition for the treatment of Demodex blepharitis and/or acne containing tea tree oil (TTO), coconut oil, aloe barbadensis, decyl glucoside, sodium chloride, sodium lauroyl methyl isethionate, Caprylic/Capric Triglyceride, Caprylyl Glycol, Ethylhexylglycerin, and Hexylene Glycol in glycerin or in water or in a mixture of glycerin and water. The composition is used to treat Demodex blepharitis and/or acne by applying the composition to the eyelid margin and eyelashes or acne and scrubbing the eyelid margin, eyelashes, and eyelash roots or acne with the composition using any suitable cloth, wipe, sponge, brush, or cotton tipped applicator.

A composition for the treatment of Demodex blepharitis and/or acne containing tea tree oil (TTO), coconut oil, aloe barbadensis, decyl glucoside, sodium chloride, sodium lauroyl methyl isethionate, Caprylic/Capric Triglyceride, Caprylyl Glycol, Ethylhexylglycerin, and Hexylene Glycol in glycerin or in water or in a mixture of glycerin and water. The composition is used to treat Demodex blepharitis and/or acne by applying the composition to the eyelid margin and eyelashes or acne and scrubbing the eyelid margin, eyelashes, and eyelash roots or acne with the composition using any suitable cloth, wipe, sponge, brush, or cotton tipped applicator.

A composition for the treatment of Demodex blepharitis and/or acne containing tea tree oil (TTO), coconut oil, aloe barbadensis, decyl glucoside, sodium chloride, sodium lauroyl methyl isethionate, Caprylic/Capric Triglyceride, Caprylyl Glycol, Ethylhexylglycerin, and Hexylene Glycol in glycerin or in water or in a mixture of glycerin and water. The composition is used to treat Demodex blepharitis and/or acne by applying the composition to the eyelid margin and eyelashes or acne and scrubbing the eyelid margin, eyelashes, and eyelash roots or acne with the composition using any suitable cloth, wipe, sponge, brush, or cotton tipped applicator.

A betel leaf extracts composition having bactericidal, antiviral, and neutralization of virus SARS-CoV-2 properties by oral. The bactericidal, antiviral, and SARS-CoV-2 virus-neutralizing efficacy of betel leaf extract/essential oil was increased by the combination with the one or two or more active plant extracts/essential oils ingredients, 4-allylpyrocatechol (APC) ingredient, a mixture of ginger-honey, and a mixture of lemon-kumquat-cinnamon by predefined order and predetermined percentage by weight of each ingredient into an oral cavity delivery agent including a range of gum, confectionery/candy, lozenge, tablet, edible film, oral film, oral solution and oral spray solution.

A betel leaf extracts composition having bactericidal, antiviral, and neutralization of virus SARS-CoV-2 properties by oral. The bactericidal, antiviral, and SARS-CoV-2 virus-neutralizing efficacy of betel leaf extract/essential oil was increased by the combination with the one or two or more active plant extracts/essential oils ingredients, 4-allylpyrocatechol (APC) ingredient, a mixture of ginger-honey, and a mixture of lemon-kumquat-cinnamon by predefined order and predetermined percentage by weight of each ingredient into an oral cavity delivery agent including a range of gum, confectionery/candy, lozenge, tablet, edible film, oral film, oral solution and oral spray solution.

A betel leaf extracts composition having bactericidal, antiviral, and neutralization of virus SARS-CoV-2 properties by oral. The bactericidal, antiviral, and SARS-CoV-2 virus-neutralizing efficacy of betel leaf extract/essential oil was increased by the combination with the one or two or more active plant extracts/essential oils ingredients, 4-allylpyrocatechol (APC) ingredient, a mixture of ginger-honey, and a mixture of lemon-kumquat-cinnamon by predefined order and predetermined percentage by weight of each ingredient into an oral cavity delivery agent including a range of gum, confectionery/candy, lozenge, tablet, edible film, oral film, oral solution and oral spray solution.

A cancer drug for use in the treatment of cancer in which caffeic acid phenethyl ester (CAPE) is encapsulated in poly [lactic-co-glycolic acid] (PLGA) to increase its solubility in aqueous media is provided. Angiopep-2 is used as a specific ligand to increase biological activity. In an embodiment of the invention, PLGA is preferably in the form of nanoparticles, thereby ensuring better solubility.

A natural antibacterial and antiviral biological composition is provided for use in hospitals and homes, in particular a composition that includes ricinoleic acid derived from the extraction of castor oil, diethanolamine and propolis, a method for obtaining the composition, and the use thereof. The invention can be used to control various pathogenic microorganisms, such as bacteria belonging to the Staphylococcus, Pseudomonas, Enterobacter and Bacillus genera; as well as hospital-environment fungi (filamentous and yeast-like) and phytopathogenic fungi (Colletrotichum fragariae). The product can be sprayed on biotic and abiotic surfaces, and non-woven fabric can subsequently be used to remove organic matter, including microorganisms. The product can also be used to disinfect medical, dental and hospital items by immersion followed by quick rinsing.

A natural antibacterial and antiviral biological composition is provided for use in hospitals and homes, in particular a composition that includes ricinoleic acid derived from the extraction of castor oil, diethanolamine and propolis, a method for obtaining the composition, and the use thereof. The invention can be used to control various pathogenic microorganisms, such as bacteria belonging to the Staphylococcus, Pseudomonas, Enterobacter and Bacillus genera; as well as hospital-environment fungi (filamentous and yeast-like) and phytopathogenic fungi (Colletrotichum fragariae). The product can be sprayed on biotic and abiotic surfaces, and non-woven fabric can subsequently be used to remove organic matter, including microorganisms. The product can also be used to disinfect medical, dental and hospital items by immersion followed by quick rinsing.

The disclosure relates to compositions comprising 3,6,7-trimethyllumazine. In particular, Manuka honey is an example of a composition comprising 3,6,7-trimethyllumazine. The composition is useful in preventing, ameliorating or treating TG2, JAK, and/or COX-2 associated conditions. These conditions include inflammation, pain, ulcers, Crohn's disease, reflux, gingivitis, schizophrenia, neurodegenerative disorders, Alzheimer's disease, Parkinson's disease, arthritis, cardiovascular diseases and cancers.