A composition for reducing damage associated with oxidative phosphorylation. The composition comprises an upregulating compound mixture configured to upregulate an endogenous antioxidant system, an exogenous antioxidant mixture configured to inhibit oxidation of biomolecules by reactive oxygen species, and a mineral mixture configured to provide one or more cofactors to a endogenous antioxidant enzyme. The endogenous antioxidant system includes a Nrf2 transcription factors that promotes transcription of antioxidant genes.

A composition for reducing damage associated with oxidative phosphorylation. The composition comprises an upregulating compound mixture configured to upregulate an endogenous antioxidant system, an exogenous antioxidant mixture configured to inhibit oxidation of biomolecules by reactive oxygen species, and a mineral mixture configured to provide one or more cofactors to a endogenous antioxidant enzyme. The endogenous antioxidant system includes a Nrf2 transcription factors that promotes transcription of antioxidant genes.

A composition for reducing damage associated with oxidative phosphorylation. The composition comprises an upregulating compound mixture configured to upregulate an endogenous antioxidant system, an exogenous antioxidant mixture configured to inhibit oxidation of biomolecules by reactive oxygen species, and a mineral mixture configured to provide one or more cofactors to a endogenous antioxidant enzyme. The endogenous antioxidant system includes a Nrf2 transcription factors that promotes transcription of antioxidant genes.

The present invention provides a method of treating and/or preventing pulmonary hypertension in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of a bioactive peptide preparation derived from at least one botanical source.

The present invention provides a method of treating and/or preventing pulmonary hypertension in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of a bioactive peptide preparation derived from at least one botanical source.

The present invention provides a method of treating and/or preventing pulmonary hypertension in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of a bioactive peptide preparation derived from at least one botanical source.

The invention relates to an extract of Ashwagandha that exhibit enhanced bioactivity and bioavailability comprising of enriched withanolide glycosides and saponins; with negligible amount of alkaloids, withanolide aglycones and oligosaccharides. The extract as disclosed prepared from root, stems, leaves and whole plant of Ashwagandha further shows improved immunomodulatory activity, anti-inflammatory activity, anti stress activity, antidiabetic activity and sleep quality. The disclosure also provides a method of improving bioactivity of withanolide glycosides even at lower doses, by the administration of an enteric coated formulation of extract of Ashwagandha to humans. The enteric coating protects the composition from hydrolysis in the acidic environment of the stomach to release the withanolide glycoside in neutral/ alkaline pH in gastrointestinal tract (GIT) thus enhancing the absorption. Further the process of preparation of the extract of Ashwagandha enriched with withanolide glycosides and saponins are disclosed along with various formulations.

A betel leaf extracts composition having bactericidal, antiviral, and neutralization of virus SARS-CoV-2 properties by oral. The bactericidal, antiviral, and SARS-CoV-2 virus-neutralizing efficacy of betel leaf extract/essential oil was increased by the combination with the one or two or more active plant extracts/essential oils ingredients, 4-allylpyrocatechol (APC) ingredient, a mixture of ginger-honey, and a mixture of lemon-kumquat-cinnamon by predefined order and predetermined percentage by weight of each ingredient into an oral cavity delivery agent including a range of gum, confectionery/candy, lozenge, tablet, edible film, oral film, oral solution and oral spray solution.

A betel leaf extracts composition having bactericidal, antiviral, and neutralization of virus SARS-CoV-2 properties by oral. The bactericidal, antiviral, and SARS-CoV-2 virus-neutralizing efficacy of betel leaf extract/essential oil was increased by the combination with the one or two or more active plant extracts/essential oils ingredients, 4-allylpyrocatechol (APC) ingredient, a mixture of ginger-honey, and a mixture of lemon-kumquat-cinnamon by predefined order and predetermined percentage by weight of each ingredient into an oral cavity delivery agent including a range of gum, confectionery/candy, lozenge, tablet, edible film, oral film, oral solution and oral spray solution.

A betel leaf extracts composition having bactericidal, antiviral, and neutralization of virus SARS-CoV-2 properties by oral. The bactericidal, antiviral, and SARS-CoV-2 virus-neutralizing efficacy of betel leaf extract/essential oil was increased by the combination with the one or two or more active plant extracts/essential oils ingredients, 4-allylpyrocatechol (APC) ingredient, a mixture of ginger-honey, and a mixture of lemon-kumquat-cinnamon by predefined order and predetermined percentage by weight of each ingredient into an oral cavity delivery agent including a range of gum, confectionery/candy, lozenge, tablet, edible film, oral film, oral solution and oral spray solution.