The present invention relates to a pharmaceutical composition, a pharmaceutical composition for animals, and a food composition, each composition comprising a Scutellaria baicalensis extract, a Liriope platyphylla extract, a Sophora flavescens extract, a Dictamnus root bark extract, and a Phellodendron amurense Ruprecht extract, and preparation methods therefor.

A pharmaceutical composition for treating oral ulcer, a preparation method and an application thereof are provided, which belong to the technical field of pharmaceutical compositions. The pharmaceutical composition includes the following raw materials: 20-50 parts of Sanhuang mixture, 15-20 parts of lotus root powder, 30-50 parts of Galla chinensis, 10-20 parts of Lonicera japonica Thunb., 10-20 parts of vanilla bean, 10-20 parts of propolis, 5-8 parts of oak bark, 5-10 parts of tea, 3-5 parts of Asarum, 1-2 parts of Atractylodes macrocephala and 5-30 parts of chlorhexidine acetate. The pharmaceutical composition for treating oral ulcer has the efficacies of clearing away heat, detoxifying removing blood stasis and reducing swelling, promoting granulation and relieving pain, inhibiting bacteria and killing bacteria, and has the advantages of quick response, easy finding of raw materials and low cost, and has a good therapeutic effect for treating oral ulcer clinically.

A pharmaceutical composition for treating oral ulcer, a preparation method and an application thereof are provided, which belong to the technical field of pharmaceutical compositions. The pharmaceutical composition includes the following raw materials: 20-50 parts of Sanhuang mixture, 15-20 parts of lotus root powder, 30-50 parts of Galla chinensis, 10-20 parts of Lonicera japonica Thunb., 10-20 parts of vanilla bean, 10-20 parts of propolis, 5-8 parts of oak bark, 5-10 parts of tea, 3-5 parts of Asarum, 1-2 parts of Atractylodes macrocephala and 5-30 parts of chlorhexidine acetate. The pharmaceutical composition for treating oral ulcer has the efficacies of clearing away heat, detoxifying removing blood stasis and reducing swelling, promoting granulation and relieving pain, inhibiting bacteria and killing bacteria, and has the advantages of quick response, easy finding of raw materials and low cost, and has a good therapeutic effect for treating oral ulcer clinically.

A method of preparing a Paris polyphylla saponin extract includes: (1) adding Paris polyphylla saponin in 60-90% ethanol to obtain a mixture, heating the mixture under reflux for 2-4 hours; (2) concentrating the mixture to ¼ volume, centrifuging the mixture to obtain a supernatant A and a precipitate A, adding the precipitate A to 60-80% ethanol to obtain a supernatant B and a precipitate B, washing the precipitate B with water and petroleum ether and drying; and (3) combining the supernatant A and the supernatant B, mixing with a macroporous adsorption resin, loading to a chromatography column, eluting the chromatography column with water and 80-90% ethanol, collecting an ethanol eluent, concentrating the ethanol eluent to obtain an eluent extract, and combining the eluent extract and the precipitate B and drying to obtain the Paris polyphylla saponin extract.

A method of preparing a Paris polyphylla saponin extract includes: (1) adding Paris polyphylla saponin in 60-90% ethanol to obtain a mixture, heating the mixture under reflux for 2-4 hours; (2) concentrating the mixture to ¼ volume, centrifuging the mixture to obtain a supernatant A and a precipitate A, adding the precipitate A to 60-80% ethanol to obtain a supernatant B and a precipitate B, washing the precipitate B with water and petroleum ether and drying; and (3) combining the supernatant A and the supernatant B, mixing with a macroporous adsorption resin, loading to a chromatography column, eluting the chromatography column with water and 80-90% ethanol, collecting an ethanol eluent, concentrating the ethanol eluent to obtain an eluent extract, and combining the eluent extract and the precipitate B and drying to obtain the Paris polyphylla saponin extract.

New compositions containing an extract of Tulipa Gesneriana. The compositions include a tulip extract from the Tulipa Gesneriana family, acetyl-tetrapeptide-2, and acetyl-hexapeptide-51 amide. Also, the use thereof in cosmetics, and the use thereof in pharmaceuticals, particularly in dermatology for treating or preventing skin aging, and the use thereof in pharmaceuticals, particularly in dermatology, for treating or preventing pathologies linked to oxidative stress.

New compositions containing an extract of Tulipa Gesneriana. The compositions include a tulip extract from the Tulipa Gesneriana family, acetyl-tetrapeptide-2, and acetyl-hexapeptide-51 amide. Also, the use thereof in cosmetics, and the use thereof in pharmaceuticals, particularly in dermatology for treating or preventing skin aging, and the use thereof in pharmaceuticals, particularly in dermatology, for treating or preventing pathologies linked to oxidative stress.

Disclosed embodiments concern a composition and/or combination, and a method of administering the same as a feed, or to supplement the feed of, aquatic animals, particularly for aquaculture. Disclosed composition and/or combination embodiments may comprise glucan, silica, mineral clay, mannans, yucca, quillaja, a probiotic, and/or an adhesive agent. The adhesive agent may be selected particularly to facilitate administration to aquatic species. In certain embodiments the adhesive agent comprises an oil, such as soy oil, or a syrup, such as molasses, or combinations thereof. In some embodiments the composition and/or combination may further comprise polyphenol, an antimicrobial, and/or a vaccine. Also disclosed is a method for promoting growth and/or immune function in aquatic animals.

Disclosed embodiments concern a composition and/or combination, and a method of administering the same as a feed, or to supplement the feed of, aquatic animals, particularly for aquaculture. Disclosed composition and/or combination embodiments may comprise glucan, silica, mineral clay, mannans, yucca, quillaja, a probiotic, and/or an adhesive agent. The adhesive agent may be selected particularly to facilitate administration to aquatic species. In certain embodiments the adhesive agent comprises an oil, such as soy oil, or a syrup, such as molasses, or combinations thereof. In some embodiments the composition and/or combination may further comprise polyphenol, an antimicrobial, and/or a vaccine. Also disclosed is a method for promoting growth and/or immune function in aquatic animals.

Disclosed embodiments concern a composition and/or combination, and a method of administering the same as a feed, or to supplement the feed of, aquatic animals, particularly for aquaculture. Disclosed composition and/or combination embodiments may comprise glucan, silica, mineral clay, mannans, yucca, quillaja, a probiotic, and/or an adhesive agent. The adhesive agent may be selected particularly to facilitate administration to aquatic species. In certain embodiments the adhesive agent comprises an oil, such as soy oil, or a syrup, such as molasses, or combinations thereof. In some embodiments the composition and/or combination may further comprise polyphenol, an antimicrobial, and/or a vaccine. Also disclosed is a method for promoting growth and/or immune function in aquatic animals.