It is an object of the present disclosure to provide an agent for coloring keratinous material, in particular human hair, comprising (a1) at least one amino-functionalized silicone polymer, and (a2) at least pigment,
the weight ratio of all the pigments (a2) contained in the composition to all the amino-functionalized silicone polymers (a1) contained in the composition, i.e., the weight ratio (a2)/(a1), being not more than 0.95.

A second subject matter is a method for dyeing keratin material, wherein the agent is applied to the keratin material.

Solid concentrated compositions of foaming cleansers, methods for preparing such solid concentrated compositions, and methods for forming liquid cleansing solutions from such solid concentrated compositions are provided. An exemplary solid concentrated composition includes a surfactant and a dissolution promotion agent, wherein the composition is anhydrous, and wherein the composition is substantially free of sulfates.

An effective treatment for dandruff and seborrheic dermatitis, a composition for treating dandruff, and a method for making such a composition

The present invention provides compounds and methods of use thereof for the treatment, prevention, and/or reduction of a risk of a disease, disorder, or condition in which aldehyde toxicity is implicated in the pathogenesis, including ocular disorders, skin disorders, conditions associated with injurious effects from blister agents, and autoimmune, inflammatory, neurological and cardiovascular diseases by the use of a primary amine to scavenge toxic aldehydes, such as MDA and HNE.

A dispersion stabiliser precursor composition including one or more of cucurbituril, a variant or a derivative thereof, and one or more oil-in-water macromolecular amphiphilic emulsifier, wherein the composition is in the form of a free flowing powder; and an oil-in-water emulsion composition including one or more of cucurbituril, a variant or a derivative thereof, and one or more oil-in-water macromolecular amphiphilic emulsifier.

Disclosed are TRPM8 modulators as defined by formula (I) for achieving a cooling effect on skin and mucosa.

Provided is a method for inhibiting the growth of Gram-positive bacteria, including contacting said bacteria with a first compound and a second compound, wherein the first compound is a compound of Formula I:

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and the second compound is an antibiotic other than a compound of Formula I. Also provided is a composition including the first compound and the second compound.

A method for dyeing hair is disclosed. The method comprises (1) treating hair with an oxidative colorant agent (A); (2) subsequent to (1), treating the hair with a CH-acidic hair dyeing agent (B); and (3) subsequent to (2), treating the hair with a cosmetic decolorizing agent (Ox). The method comprises a time interval between (1) and (2) of from about 1 minute to about 1.5 months, and a time interval between (2) and (3) of from about 1 minute to about 1.5 months. A process for multitonal dyeing of hair is also disclosed. The process comprises preparing an oxidative colorant agent (A); treating hair with the agent (A) to give a colored hair; preparing a CH-acidic hair dyeing agent (B); treating the colored hair with the agent (B) to give a dyed hair; and treating the dyed hair with a cosmetic decolorizing agent (Ox) to give a multitonal dyed hair.

Provided are compounds of formula (I), (Ia), (Ib), and (Ic), and pharmaceutically and/or cosmeceutically acceptable salts thereof. Additionally provided are pharmaceutical and/or cosmeceutical compositions and formulations, comprising the compounds and/or salts thereof, therapeutic and/or cosmetic methods using same for modulating (e.g., inhibiting) CREB binding protein (CBP)/β-catenin mediated signaling in treating skin related diseases, conditions or disorders (e.g., dermatitis, psoriasis, scarring, alopecia, etc.) mediated by aberrant CBP/β-catenin signaling, and cosmetic methods for treating skin conditions (e.g., aging, etc.) mediated by aberrant CBP/β-catenin signaling.

The objective of the present disclosure is a multi-component packaging unit (kit-of-parts) for dyeing keratinous material, in particular human hair, comprising separately prepared a first container comprising an agent (a), wherein the agent comprises (a): (a1) at least one amino-functionalized silicone polymer, and a second container comprising an agent (b), wherein the agent comprises (b): (b1) Water and (b2) a buffer system comprising at least one inorganic or organic acid (b2-I) and at least one salt of this acid (b2-II), and (b3) at least one color-imparting compound.

A second objective of the present disclosure is a corresponding method in which the two agents (a) and (b) are used.