A novel cosmetic skin care composition is provided which comprises a solubilized lipophilic peptide, preferably palmitoyl peptide, preferably palmitoyl-GHK-Cu, at a concentration in the range of 0.2-1.1%, the formulation being substantially free of alcohols or preservatives. A method of formulating the composition is also provided to provide a high concentration of the peptide in the final composition.

The present invention relates to a fragrance or flavor composition comprising a fragrance or flavor component acting on at least one olfactory receptor polypeptide selected from the group consisting of (a) OR2C1 and OR4Q3, and (b) polypeptides which comprise an amino acid sequence sharing an identity of at least 80% with the amino acid sequence of any of the polypeptides in (a) and which are responsive to at least one offensive odor-causing substance selected from the group consisting of trans-2-nonenal, trans-2-octenal, 1-octen-3-one, 1,5-octadien-3-one, 1-octen-3-ol and 1,5-octadien-3-ol to suppress the response intensity of the olfactory receptor polypeptide(s) to at least one of the offensive odor-causing substances, and also relates to a product comprising this fragrance or flavor composition and a method for suppressing offensive odors.

Dental appliance cleansing composition comprising (a) fatty acid isopropyl ester, (b) polyoxyethylene sorbitan ester, (c) second sorbitan ester, wherein the cleansing composition does not contain methanol, ethanol or isopropyl alcohol. Dental appliance cleansing wipe impregnated with the composition. Use of the dental appliance cleansing composition or wipe for cleaning dental appliances and dentures.

i) an alkali metal salt of an aldonic acid; ii) 0.1 to 5 wt %, citric acid by weight of the total composition; and iii) a surfactant; wherein the composition has a pH of from 3 to 5, provides repair to damaged internal protein of hair.

The present invention relates to a pharmaceutical composition comprising piperonylic acid as an effective ingredient for anti-aging or regenerating the skin. A composition according to the present invention utilizes piperonylic acid that various plant species naturally contain therein and thus does not cause side effects. Piperonylic acid activates signals associated with cell survival, growth, and proliferation to exhibit the effect of increasing the resistance and survival of skin cells against external stimuli and enhancing the regeneration of the skin damaged due to external stimuli or senescence. In addition, piperonylic acid of the present invention has a similar function to EGF, but is stable and small in size in contrast to EGF. Thus, piperonylic acid of the present invention has the advantage of being able to easily move to the skin basal layer across the skin barrier and perform its function. Piperonylic acid of the present invention is expected to find applications in various fields including medicines, quasi-drugs, cosmetics, cosmetic substances, functional biomaterials, and functional food materials. In addition, the present invention provides a use of piperonylic acid for preventing hair loss or promoting hair growth. Piperonylic acid is a component derived from natural products, is safe, has few side effects, and has an effect of effectively improving androgenic alopecia symptoms, and the like, and thus can be used in various applications such as a cosmetic, drug, quasi-drug or food for preventing hair loss or promoting hair growth.

Embodiments of the present disclosure recite medicated cosmetic skin creams containing Yel002, methods of manufacturing said creams, and methods of using said skin creams.

An agent for dyeing keratinous material, in particular human hair, is disclosed. The agent is a colorant composition comprising at least one amino-functionalized silicone polymer, at least one color-imparting compound, and at least one organic carbonic acid ester. A process (method) for dyeing keratinous material with the agent is also disclosed. The process includes applying a colorant comprising the agent to the keratinous material, exposing the keratinous material to the agent for an exposure time sufficient for the color-imparting compound to act on the keratinous material, and rinsing out the keratinous material with water.

An external skin preparation comprises the following components (A) to (E), wherein the mass ratio of the component (A) to the component (B), (A)/(B), is from 0.3 to 2.0, wherein the content of the component (C) is from 0.1 to 1 mass %, and wherein the preparation has a pH at 25° C. of from 4.0 to 7.0: (A) one or more selected from the group consisting of aliphatic alcohols having from 14 to 20 carbon atoms; (B) two or more selected from the group consisting of polyhydric alcohol fatty acid ester-type nonionic surfactants; (C) one or more selected from the group consisting of N-acyl amino acids, N-acyl taurine, salts thereof, and phospholipids; (D) one or more selected from the group consisting of steroidal anti-inflammatory drugs, non-steroidal anti-inflammatory drugs, and heparinoids; and (E) water.

The invention relates to compositions comprising certain sorbitan carboxylic esters and glycerol carboxylic esters in particular amounts.

Disclosed herein are nanoemulsions, the nanoemulsions comprising biologically active ingredients. Further disclosed are processes for preparing the nanoemulsions and methods of their use.