Disclosed is a dissolvable, gel-forming film, and methods for its use, comprising a water-soluble cellulose ether, a hydrophilic rheological modifying agent, and an active proteolytic enzyme or other drug substance. The gel-forming film has a water content of less than 15% w/w and is capable of forming a hydrogel when contacted with water or other aqueous medium. The disclosed films achieve delivery of stable proteolytic enzymes to the desired site of action in a manner that provides uniform delivery of the enzymes.

The cross-linked polymer compound according to the present invention includes skeleton units of Formula (1)-(2),

##STR00001## wherein R.sup.1 is one or more selected from hydrogen, an alkyl group, a hydroxy group, an amino group, a mercapto group, a substituted carbonyl group, and any alkyl group having, as a substituent, one or more selected from a hydroxy group, an amino group, a mercapto group, and a substituted carbonyl group; X is one or more selected from —COO.sup.−, —SO.sub.3.sup.−, and —P(═O)(O.sup.−).sub.2; and Y is one or more selected from Li.sup.+, Na.sup.+, and K.sup.+, and

##STR00002## wherein R.sup.2 are each independently one or more selected from hydrogen, an alkyl group, a hydroxy group, an amino group, a mercapto group, a substituted carbonyl group, and any alkyl group having, as a substituent, one or more selected from a hydroxy group, an amino group, a mercapto group, and a substituted carbonyl group.

The cross-linked polymer compound according to the present invention includes skeleton units of Formula (1)-(2),

##STR00001## wherein R.sup.1 is one or more selected from hydrogen, an alkyl group, a hydroxy group, an amino group, a mercapto group, a substituted carbonyl group, and any alkyl group having, as a substituent, one or more selected from a hydroxy group, an amino group, a mercapto group, and a substituted carbonyl group; X is one or more selected from —COO.sup.−, —SO.sub.3.sup.−, and —P(═O)(O.sup.−).sub.2; and Y is one or more selected from Li.sup.+, Na.sup.+, and K.sup.+, and

##STR00002## wherein R.sup.2 are each independently one or more selected from hydrogen, an alkyl group, a hydroxy group, an amino group, a mercapto group, a substituted carbonyl group, and any alkyl group having, as a substituent, one or more selected from a hydroxy group, an amino group, a mercapto group, and a substituted carbonyl group.

The present disclosure provides a biodegradable super absorbent polymer including a crosslinked polymer of a monomer including a modified polysaccharide having a maleic acid group (—OCOCH═CHCOOH) and a sulfosuccinic acid group (—OCOCH(SO.sub.3H)CH.sub.2COOH), which exhibits excellent biodegradability without deterioration in physical properties of the super absorbent polymer such as centrifuge retention capacity and absorbency under pressure, and a method for producing the same.

A biodegradable disposable diaper includes an inner layer comprising a soft, non-woven fabric, the inner layer for resting against a wearer's skin and allowing the passage of bodily waste fluids, a middle layer comprising superabsorbent polymer for absorbing and retaining the bodily waste fluids, an outer layer comprising a liquid impermeable membrane, the outer layer for restricting the passage of bodily waste fluids, and a frangible capsule, dispenser or packet containing a substance comprising mycelium, fungal spores and/or enzymes configured for using bodily waste to grow and degrading the biodegradable disposable diaper in a disposal environment, the frangible capsule, dispenser or packet further for allowing the deposition of the substance into the diaper at the time of disposal. A substance configured for using bodily waste to grow and degrading a biodegradable disposable diaper in a disposal environment, the substance configured for deposition onto the diaper.

A biodegradable disposable diaper includes an inner layer comprising a soft, non-woven fabric, the inner layer for resting against a wearer's skin and allowing the passage of bodily waste fluids, a middle layer comprising superabsorbent polymer for absorbing and retaining the bodily waste fluids, an outer layer comprising a liquid impermeable membrane, the outer layer for restricting the passage of bodily waste fluids, and a frangible capsule, dispenser or packet containing a substance comprising mycelium, fungal spores and/or enzymes configured for using bodily waste to grow and degrading the biodegradable disposable diaper in a disposal environment, the frangible capsule, dispenser or packet further for allowing the deposition of the substance into the diaper at the time of disposal. A substance configured for using bodily waste to grow and degrading a biodegradable disposable diaper in a disposal environment, the substance configured for deposition onto the diaper.

The present disclosure provides a magnetic dressing and a preparation method and use thereof, belonging to the technical field of pharmaceutical preparations. The magnetic dressing includes a magnetic layer, a drug-loading layer, and a protective layer that are stacked in sequence, where the magnetic layer includes polyvinyl alcohol, gluten, and iron particles. In the present disclosure, a swallowed magnetic dressing is controlled by an external magnetic field, and the magnetic dressing is moved to a pathological position by changing a direction of the external magnetic field; after the external magnetic field is removed, the magnetic dressing changes from a ring to a sheet, thereby completing attachment of an entire lesion surface to complete treatment by autonomous drug release.

The present disclosure provides a magnetic dressing and a preparation method and use thereof, belonging to the technical field of pharmaceutical preparations. The magnetic dressing includes a magnetic layer, a drug-loading layer, and a protective layer that are stacked in sequence, where the magnetic layer includes polyvinyl alcohol, gluten, and iron particles. In the present disclosure, a swallowed magnetic dressing is controlled by an external magnetic field, and the magnetic dressing is moved to a pathological position by changing a direction of the external magnetic field; after the external magnetic field is removed, the magnetic dressing changes from a ring to a sheet, thereby completing attachment of an entire lesion surface to complete treatment by autonomous drug release.

The present application provides a method for preparing a medical product for covering tissue, the method comprising providing nanofibrillar cellulose, providing a bioactive molecule, and covalently bonding the bioactive molecule to the nanofibrillar cellulose. The present application also provides a medical product for covering tissue comprising a bioactive molecule covalently bound to nanofibrillar cellulose.

The present disclosure relates to an environmentally friendly sanitary napkin including: a permeable inner sheet configured to come into contact with a skin and allow secretions to pass therethrough; an impermeable waterproof outer sheet having the same size and shape as those of the inner sheet and bonded to the inner sheet by fusion; an absorbent pad fixedly inserted between the inner sheet and the waterproof outer sheet and configured to absorb secretions such as menstrual blood that passes through the inner sheet; and an adhesive pad inserted into an appropriate position between the absorbent pad and the waterproof outer sheet, and provided on the absorbent pad and the lower surface of the waterproof outer sheet, and configured to fix the sanitary napkin by adhesion to the inside of underwear, wherein the inner sheet, the waterproof outer sheet, the absorbent pad and the adhesive pad are degradable in water or are biodegradable.

The environmentally friendly sanitary napkin of the present disclosure is degradable by a large amount of water in a septic tank when flushed down a toilet bowl after use, and is biodegradable in soil, thus preventing environmental pollution problems.

In addition, the environmentally friendly sanitary napkin may exhibit antimicrobial effects against harmful bacteria in the vagina and exhibit an excellent effect on sanitariness by suppressing the generation of odor caused by secretions.