An apparatus such as a fluid mixer, suitable for use with a respirator, including a venturi nozzle for flow of a pressure-controlled fluid; an ambient fluid aperture in fluid communication with the venturi nozzle; a fluid port; a pressure force multiplier in fluid communication with the fluid port; and a valve moveable relative to the venturi nozzle between a start flow position and a stop flow position; where the pressure force multiplier is configured such that fluid forced into the fluid port actuates the valve relative to the venturi nozzle; and where the pressure force multiplier is configured such that fluid withdrawn from the fluid port actuates the valve relative to the venturi nozzle. An attachment device, connector, and method of using an apparatus suitable for a ventilator is also disclosed.

The present disclosure provides a manifold that can be easily attached to a medical or dental chair in which a patient sits and a flexible arm and funnel connected to the manifold and configured to receive a High Volume Evacuator (HVE) tube. The flexible arm which holds the funnel is configured to be sufficiently rigid to maintain its shape and position, allowing a clinical practitioner to leave the funnel in the appropriate place to capture aerosols emitted from a patient during a procedure use the negative pressure from the HVE. Thus, also provided herein is a method of using the disclosed manifold to remove aerosols emitted during a clinical procedure.

A CPAP system for respiratory therapy includes an RPT device configured to supply a flow of gas at a therapeutic pressure, a patient interface, an air delivery conduit configured to pass the flow of gas from the RPT device to the patient interface, and a vent assembly configured to provide a vent flow of gas to discharge gas exhaled by the patient from a pressurized volume to ambient. The vent assembly includes a base including at least one first orifice to allow gas to be discharged along a primary vent flow path and at least one second orifice to allow gas to be discharged along a secondary vent flow path, a diffusing member provided to the base, and a membrane provided to the base. The membrane is configured to apportion the vent flow of gas along the primary vent flow path and the secondary vent flow path throughout respiratory therapy.

A CPAP system for respiratory therapy includes an RPT device configured to supply a flow of gas at a therapeutic pressure, a patient interface, an air delivery conduit configured to pass the flow of gas from the RPT device to the patient interface, and a vent assembly configured to provide a vent flow of gas to discharge gas exhaled by the patient from a pressurized volume to ambient. The vent assembly includes a base including at least one first orifice to allow gas to be discharged along a primary vent flow path and at least one second orifice to allow gas to be discharged along a secondary vent flow path, a diffusing member provided to the base, and a membrane provided to the base. The membrane is configured to apportion the vent flow of gas along the primary vent flow path and the secondary vent flow path throughout respiratory therapy.

An apparatus and method for providing heat exchange in the lungs of the mammal during partial liquid ventilation are provided. The apparatus and method can control delivery and removal of partial liquid ventilation to the lungs of a mammal by responding to pressure change in the lungs to minimize danger of causing barotrauma to the patient.

A method of circulating a flow of blood within a circulatory system of a body includes applying an extrathoracic pressure to the body with a fluid. An intrathoracic pressure is applied to the body with the fluid. The application of the extrathoracic pressure relative to the application of the intrathoracic pressure is varied, so as to circulate a flow of blood within the circulatory system of the body.

Systems and methods for generating MRI images of the lungs and/or airways of a subject using a medical grade gas mixture comprises between about 20-79% inert perfluorinated gas and oxygen gas. The images are generated using acquired .sup.19F magnetic resonance image (MRI) signal data associated with the perfluorinated gas and oxygen mixture.

Liquid ventilator and methods integrating the concept of total liquid ventilation (TLV) using liquid volumes below functional residual capacity (FRC) of mammal's lungs are disclosed. Beyond the automatization of the whole process, the technology has been up-scaled to confirm that TLV at residual volumes below FRC can provide a safe procedure while enabling the full potential of TLV in a mammal such as humans or adult-sized animals. Such tidal liquid ventilation strongly differs from the previously known TLV approach, opening promising perspectives for a safer clinical translation. Also disclosed are apparatus and method for safe and fast induction of hypothermia during liquid ventilation of a mammal.

Helically winding an extruded web to form a wall of a heated hose about a central axis, extruding a bead of plastics material around a heating wire such that the extruded bead comprises the heating wire at a first location within a cross-section of the extruded bead, helically winding the extruded bead onto the wall of the hose to provide a support helix, and exerting tension on the heating wire to draw down the heating wire toward the central axis such that the heating wire migrates radially inward from the first location to a second location within the cross-section of the extruded bead.

An aerosol delivery system, which includes an aerosol delivery unit, the aerosol delivery unit including: a cartridge receiver, which is configured to receive a cartridge assembly; and an inductor configured to receive the cartridge assembly and heat a liquid formulation within a capillary tube to produce an aerosol by induction heating. The cartridge assembly including an active part of the cartridge assembly including a capillary tube; a susceptor, the susceptor configured to partially surround the capillary tube; and a pair of displaceable covers, which surround at least the capillary tube and the susceptor.