A method of manufacturing a catheter shaft includes the steps of forming an inner layer of a first polymeric material, forming a plait matrix layer including a second polymeric material about the inner layer, and forming an outer layer of a third polymeric material about the plait matrix layer. The plait matrix layer includes a braided wire mesh partially or fully embedded within the second polymeric material, which is different from at least one of the first polymeric material forming the inner layer and the third polymeric material forming the outer layer. The second polymeric material has a higher yield strain and/or a lower hardness than at least the first polymeric material, and preferably both the first and the third polymeric materials. The first polymeric material and the third polymeric material may be different or the same. The catheter shaft may be formed by stepwise extrusion, co-extrusion, and/or reflow processes.

Various embodiments of a device, a kit and method for delivering a drug depot are disclosed. The device comprises a housing including a lower body, an upper body, a ring member; and a drug cartridge. The lower body defines a lower body channel. The upper body defines an upper body channel. The drug cartridge defines a depot channel. The ring member is disposed extending upward from an annular step surface of the lower body toward a housing upper end. The ring member includes indicia indicating a characteristic of one or more drug depots in the drug cartridge. A plunger has a push rod for expelling the drug depot through the cannula to a site in the patient. A kit comprises the above components. A method includes assembling the components including selecting a ring member having indicia corresponding to one or more drug depots in the drug cartridge.

The present disclosure relates to a catheter coupler and methods of exchanging catheters within a patient with a replacement catheter. The catheter coupler is configured to couple to a first catheter that has been disposed within a patient and coupled to a second or replacement catheter. Once the coupler is coupled to the first and second catheter, the first catheter may be withdrawn from the patient, which simultaneously advances the second or replacement catheter into the previous position of the first catheter. The coupler may include a body with a first end and a second end. The coupler may have a plurality of barbs disposed on both ends of the body of the coupler, wherein the barbs are configured to couple the coupler to the lumen of the catheters.

Sphincterotomes and methods for making and using sphincterotomes are disclosed. An example sphincterotome may include an elongate shaft having an outer surface and a distal end region. The sphincterotome may also include a sphincterotome wire assembly having a distal end coupled to the distal end region of the elongate shaft and a body portion extending along the outer surface of the elongate shaft. The sphincterotome wire assembly may be designed to shift the distal end region of the elongate shaft between a first configuration and a curved configuration. The body portion of the sphincterotome wire assembly may include a cutting region and a nonconductive region.

A system and method for determining an access trajectory to a target site to safely place a surgical access instrument (e.g., guide wire, dilator, cannula, etc.) through a tissue (e.g., muscle, fat, brain, liver, lung, etc.) without damaging nearby neurovascular structure is described herein. The trajectory determination system includes a nerve stimulation probe and a dilator guide having a plurality of guide channels and registerable to an operating table in a fixed orientation. Motor nerve stimulation (e.g., EMG, MMG) is performed with the stimulation probe positioned in each of said plurality of guide channels to generate a map of nerve locations within intervening anatomical structures (e.g., muscle, bone, etc.) between the dilator guide and the surgical target site. Available access pathways are determined based on the nerve location data and displayed on a display unit.

An apparatus for a heart of a patient having a cardiac assist device adapted to be implanted into the patient to assist the heart with pumping blood. The apparatus has a sensor adapted to be implanted into the patient. The sensor in communication with the cardiac assist device and the heart which measures native volume of the heart. Alternatively, the sensor monitors the heart based on admittance while the cardiac assist device. Alternatively, the sensor monitors the heart based on impedance.

The present teachings provide a catheter shaft design and configuration for use in the delivering and deploying a medical device, and aspiration removal of occlusion. Specifically, one aspect of the present teachings provides a catheter shaft design having a four-layer construction, an ultra-thin inner layer, a first coil middle layer, and a second braid middle layer, and an outer jacket layer. The first coil middle layer of the catheter shaft is made of a flat wire with width to thickness ratio of at least 2:1. The outer jacket layer of the catheter shaft is made of three different material with a soft durometer forming the distal portion of the outer jacket, a medium durometer material forming the middle/transitional portion of the outer jacket, and a stronger durometer material forming the proximal portion of the outer jacket.

Sheath assembly for the insertion of a cord-shaped element, comprising an introducer sheath, and an auxiliary sheath for insertion into the introducer sheath together with the cord-shaped element. In some examples, the auxiliary sheath has a housing configured to detachably couple to the introducer sheath housing, and to detachably fasten the cord-shaped element with respect to the auxiliary sheath housing.

A catheter and tissue cutting system percutaneously permits the creation of an anastomosis between a first and second anatomical structure, such as a vein and an artery. The system comprises a catheter having a main body with a lumen and tapered distal tip, configured to be moved distally into the first anatomical structure over a primary guidewire. A cutting electrode is nested in the main body, with a lumen which tracks over a secondary guidewire, and is insertable into the secondary anatomical structure. An energy supply is operative to energize the cutting electrode in order to cut a tissue wall defining the first anatomical structure.

Methods of making and using a bougie having a body with a first insertion depth indicator spaced a first distance from a first end of the body and configured to indicate a first predetermined insertion depth range, and a second insertion depth indicator spaced a second distance from a second end of the body and configured to indicate a second predetermined insertion depth range that is different from the first predetermined insertion depth range are described. To use the bougie, a user determines whether or not the first or second predetermined insertion depth range is appropriate for the patient, and then inserts the appropriate one of the first end or the second end of the body into the mouth of the patient.