An external end device has a casing (4), a fitting (15) housed in the casing (4) and having at least one distal part (16) which engages a catheter (3), and two proximal tracts (17, 17), in which a pair of curved pipes (18, 18) are inserted with a distal end (180) thereof. The curved pipes (18, 18) have a proximal end (181), in which a pair of nozzles (190, 190) are inserted. Inside each nozzle (190) there is a cap (20) suitable for hermetically sealing the nozzle (190). A piercing and connecting conduit (24) is adapted to reversibly pierce the cap (20) and to connect the pair of nozzles (190, 190) to the flow lines of the treatment equipment. Also disclosed is a method of connecting the external terminal device to flow lines of a machine.

Method and devices for viewing one or more valve leaflets via a viewer. In some embodiments the viewer includes a body having a first end and a second end opposite the first end, the first end being closed and having a transparent viewing window, the second end arranged to be attached to an aorta or a pulmonary artery, and one or more ports arranged to provide fluid access to an internal portion of the viewer to pressurize the one or more leaflets. A diameter of the viewing window is larger than an outer diameter of the second end. An outer diameter of the first end of the body is larger than an outer diameter of the second end. The body is a tubular body.

A biopharmaceutical flow port, a biopharmaceutical liquid container assembly, and a method for manufacturing the biopharmaceutical flow port and the biopharmaceutical liquid container assembly are described. The biopharmaceutical flow port includes a hose barb coupled to an elliptic body. The hose barb includes a bore. The elliptic body includes a flow passage, a first edge, and a second edge. The flow passage is fluidly coupled to the bore. The first edge extends from the elliptic body away from the flow passage in a first direction and the second edge extends from the elliptic body away from the flow passage in a second direction opposite the first direction. The biopharmaceutical liquid container assembly includes a biopharmaceutical liquid container with an opening and the biopharmaceutical flow port coupled to the biopharmaceutical liquid container within the opening and in fluid communication with a volume of the biopharmaceutical liquid container.

An adapter for connecting a first connector to a second connector can include a proximal portion configured to linearly engage the first connector with a snap-fit engagement. The adapter can include a distal portion configured to rotationally engage the second connector. Rotation of the adapter relative to the second connector can advance a male luer of the first connector into substantially sealing engagement with a female luer on the second connector. The adapter can be configured to displace a collar on the first connector when coupled to the first connector. The second connector can include a proximal portion that is configured to engage the first connector, such as with a snap-fit engagement.

An adapter for connecting a first connector to a second connector can include a proximal portion configured to linearly engage the first connector with a snap-fit engagement. The adapter can include a distal portion configured to rotationally engage the second connector. Rotation of the adapter relative to the second connector can advance a male luer of the first connector into substantially sealing engagement with a female luer on the second connector. The adapter can be configured to displace a collar on the first connector when coupled to the first connector. The second connector can include a proximal portion that is configured to engage the first connector, such as with a snap-fit engagement.

An integrated catheter assembly includes a housing member, an outer lumen member extending from the housing member, and a needle member slidably or movably coupled to the housing member, wherein the needle member can be extended beyond a first port of the outer lumen member in a first position and concealed in the outer lumen member in a second position. The outer lumen member has a side port between its first and second ports such that when the needle is extended in the first position and inserted into an arteriovenous fistula, blood from the arteriovenous fistula flashes into the needle member, is diverted through a relief port of the needle member out the side port of the outer lumen member for delivery to a dialysis machine. The assembly further includes an inner lumen member that is disposable through the housing member to extend out from the same the outer lumen member to provide dialyzed blood from the machine. The assembly therefore receives and delivers blood through a single injection site.

An integrated catheter assembly includes a housing member, an outer lumen member extending from the housing member, and a needle member slidably or movably coupled to the housing member, wherein the needle member can be extended beyond a first port of the outer lumen member in a first position and concealed in the outer lumen member in a second position. The outer lumen member has a side port between its first and second ports such that when the needle is extended in the first position and inserted into an arteriovenous fistula, blood from the arteriovenous fistula flashes into the needle member, is diverted through a relief port of the needle member out the side port of the outer lumen member for delivery to a dialysis machine. The assembly further includes an inner lumen member that is disposable through the housing member to extend out from the same the outer lumen member to provide dialyzed blood from the machine. The assembly therefore receives and delivers blood through a single injection site.

A gravity fed peritoneal dialysis (“PD”) machine includes: a frame configured to be set on a supporting surface; at least one load cell; a scale platform supported by the frame via the at least one load cell positioned between the frame and the scale platform; a drain container support in mechanical communication with and extending downwardly from the scale platform, the machine configured such that when the frame is set on the supporting surface, at least one fresh PD fluid supply container is supportable by the scale platform above the at least one load cell and at least one used PD fluid drain container is supportable by the drain container support below the at least one load cell, so that a combined weight of fresh PD fluid and used PD fluid may be sensed by the at least one load cell.

A sealing member for providing a seal between fluid connectors includes a tubular member defining a lumen extending between a first end and a second end. The tubular member may receive a first connector via the first end and a second connector via the second end, and includes an annular wall extending between a first annular portion adjacent the first end and a second annular portion adjacent the second end. The first annular portion may engage the first connector, and the second annular portion may engage the second connector. When a pressure within the lumen is negative, atmospheric acting inward on the annular wall compresses the sealing member to define a contact force between the second annular portion and the second connector sufficient to define a fluid seal between the sealing member and the second connector.

An illustrative drug delivery system implantable in a recipient may include a connection assembly, a source catheter, and a microcatheter. A proximal end portion of the source catheter may be configured to be fluidically connected to a fluid source configured to provide a fluid (e.g., a neurotherapeutic drug). A distal end portion of the source catheter may be configured to be fluidically connected to the connection assembly. The microcatheter may include a proximal end portion configured to be fluidically connected to the connection assembly and a distal end portion comprising an elution opening configured to elute the fluid to a target location (e.g., a brain) within a recipient. The fluid source may be configured to provide the fluid to the target location by way of the source catheter, the connection assembly, and the microcatheter.