An intravascular heart pump assembly can include a rotor with at least one impeller blade, and a cannula. The present application describes various cannulas that can be manufactured from multiple layers of material to improve flexibility, manufacturability, and durability without increasing an outer diameter of the cannula. In one embodiment, the cannula includes an inflow section having a sheet formed of a shape memory material embedded within a polymer and having at least one lateral hole or aperture in the inflow section. The at least one lateral hole is defined by a first hole in the sheet and a second hole in the outer polymer layer of the cannula. The first hole and the second hole overlap so that blood can enter the cannula through the holes.

An intravascular heart pump assembly can include a rotor with at least one impeller blade, and a cannula. The present application describes various cannulas that can be manufactured from multiple layers of material to improve flexibility, manufacturability, and durability without increasing an outer diameter of the cannula. In one embodiment, the cannula includes an inflow section having a sheet formed of a shape memory material embedded within a polymer and having at least one lateral hole or aperture in the inflow section. The at least one lateral hole is defined by a first hole in the sheet and a second hole in the outer polymer layer of the cannula. The first hole and the second hole overlap so that blood can enter the cannula through the holes.

An extracorporeal circulation management device pumps blood in synchronization with heartbeats of a patient based on measurements of blood flow. Maximum and minimum blood flow measurement samples are compared with upper and lower threshold values to identify candidate timing for a systolic phase and diastolic phase of the heartbeat. During pulsatile pumping of the blood using the candidate timing, differences in the pulsatile flow measurements are determined. Based on the size of the difference, a final correction may be made to identification of the systolic and diastolic phases, and the corrected phase information is used to start and stop the motor unit.

An extracorporeal circulation management device pumps blood in synchronization with heartbeats of a patient based on measurements of blood flow. Maximum and minimum blood flow measurement samples are compared with upper and lower threshold values to identify candidate timing for a systolic phase and diastolic phase of the heartbeat. During pulsatile pumping of the blood using the candidate timing, differences in the pulsatile flow measurements are determined. Based on the size of the difference, a final correction may be made to identification of the systolic and diastolic phases, and the corrected phase information is used to start and stop the motor unit.

A percutaneous circulatory support device includes an impeller housing having an inlet and an outlet. A shaft is rotatably fixed relative to the impeller housing. An impeller is configured to rotate relative to the shaft and the impeller housing to cause blood to flow into the inlet, through the impeller housing, and out of the outlet.

A percutaneous circulatory support device includes an impeller housing having an inlet and an outlet. A shaft is rotatably fixed relative to the impeller housing. An impeller is configured to rotate relative to the shaft and the impeller housing to cause blood to flow into the inlet, through the impeller housing, and out of the outlet.

A percutaneous circulatory support device includes a housing having an inlet and an outlet. A shaft is rotatably fixed relative to the housing. An impeller is disposed within the housing and is rotatably supported by the shaft. The impeller is configured to rotate relative to the shaft and the housing to cause blood to flow into the inlet, through the housing, and out of the outlet. A keeper is coupled to the shaft distally relative to the impeller, and the keeper inhibits axial motion of the impeller relative to the shaft.

A percutaneous circulatory support device includes a housing having an inlet and an outlet. A shaft is rotatably fixed relative to the housing. An impeller is disposed within the housing and is rotatably supported by the shaft. The impeller is configured to rotate relative to the shaft and the housing to cause blood to flow into the inlet, through the housing, and out of the outlet. A keeper is coupled to the shaft distally relative to the impeller, and the keeper inhibits axial motion of the impeller relative to the shaft.

An intravascular heart pump assembly can include a rotor with at least one impeller blade, and a cannula. The present application describes various cannulas that can be manufactured from multiple layers of material to improve flexibility, manufacturability, and durability without increasing an outer diameter of the cannula. In one embodiment, the cannula includes an inflow section having a sheet formed of a shape memory material embedded within a polymer and having at least one lateral hole or aperture in the inflow section. The at least one lateral hole is defined by a first hole in the sheet and a second hole in the outer polymer layer of the cannula. The first hole and the second hole overlap so that blood can enter the cannula through the holes.

An intravascular heart pump assembly can include a rotor with at least one impeller blade, and a cannula. The present application describes various cannulas that can be manufactured from multiple layers of material to improve flexibility, manufacturability, and durability without increasing an outer diameter of the cannula. In one embodiment, the cannula includes an inflow section having a sheet formed of a shape memory material embedded within a polymer and having at least one lateral hole or aperture in the inflow section. The at least one lateral hole is defined by a first hole in the sheet and a second hole in the outer polymer layer of the cannula. The first hole and the second hole overlap so that blood can enter the cannula through the holes.