A method of performing photodynamic therapy is provided. The method includes applying, to the skin of a patient, a topical composition. The topical composition includes 5-aminolevulinic acid (ALA) hydrochloride, and a vehicle comprising at least one chelating agent to enhance accumulation of protoporphyrin IX (PpIX) in the skin. The method further includes incubating the topical composition, and following incubation, applying, to the skin, heat from a heat source for at least a first time period.

Provided herein is a multifunctional aesthetic system including a housing, an electromagnetic array situated in the housing and having a plurality of electromagnetic radiation (EMR) sources, each EMR source configured to generate an EMR beam having a wavelength different than that of an EMR beam generated by another of the EMR sources, a controller in electronic communication with the array to operate two or more of the EMR sources to direct the EMR beam to a treatment area, and a sensor in electronic communication with the controller for providing feedback to the controller based on defined parameters to allow the controller to adjust at least one operating condition of the multifunctional system in response to the feedback.

The invention relates to a mouthpiece and method for antibacterial treatment of intraoral surfaces. The mouthpiece comprises a body made of heat conducting material, the body comprising tilted facial and lingual outer surfaces and facial and lingual inner surfaces adapted to face facial and lingual surfaces of teeth, respectively. A light source is attached to the body's tilted surface and adapted to deliver light to surfaces of teeth, the light source being positioned on at least one of said outer surfaces and adapted to deliver said light via said inner surfaces to both the facial and lingual surfaces of the teeth.

A method of delivering light energy to a pathological tissue includes emitting light energy from a first optical element within a cannula, producing a substantially uniform irradiance profile from the light energy within the cannula, transmitting the light energy emitted from the first optical element through a second optical element in thermal contact with a distal end of the cannula to the pathological tissue without ablating the pathological tissue, and conducting thermal energy from the pathological tissue through the second optical element and to the cannula.

An unattended approach can increase the reproducibility and safety of the treatment as the chance of over/under treating of a certain area is significantly decreased. On the other hand, unattended treatment of uneven or rugged areas can be challenging in terms of maintaining proper distance or contact with the treated tissue, mostly on areas which tend to differ from patient to patient (e.g. facial area). Delivering energy via a system of active elements embedded in a flexible pad adhesively attached to the skin offers a possible solution. The unattended approach may include delivering of multiple energies to enhance a visual appearance.

Disclosed is a high power VCSEL laser treatment device with a skin cooling function, comprising VCSEL array (4) packaged on a laser heat sink (2), an optical transmission device (8) arranged in front of light-exiting faces of the VCSEL array (4) and a high-heat-conductivity optical window sheet (6) adhered to the light-exiting port end of the optical transmission device (8). An integrally molded cooling conduction metal piece (1) is arranged on the outer sides of the laser heat sink (2), the optical transmission device (8) and the high-heat-conductivity optical window sheet (6). In addition, one or more semiconductor chilling plates (7) are arranged between the cooling conduction metal piece (1) and the laser heat sink (2). In the above-mentioned high power VCSEL semiconductor laser treatment device, the semiconductor chilling plates (7) and the VCSEL array (4) share the heat sink, so that the inner structure is simplified.

The present invention relates to an optical apparatus for skin treatment and to a method for controlling the optical apparatus. The optical apparatus includes a radiating part for radiating light generated in a light-generation part onto a target position of the skin, a cooling part for spraying cooling gas onto the target position to cool the surface of the skin, and a control part for controlling operations of the radiating part and cooling part. The control part controls the radiating part and the cooling part such that the radiating part radiates a first light onto the target position, the cooling part sprays the cooling gas onto the target position, and then the radiating part radiates a second light onto the target position.

An unattended approach can increase the reproducibility and safety of the treatment as the chance of over/under treating of a certain area is significantly decreased. On the other hand, unattended treatment of uneven or rugged areas can be challenging in terms of maintaining proper distance or contact with the treated tissue, mostly on areas which tend to differ from patient to patient (e.g. facial area). Delivering energy via a system of active elements embedded in a flexible pad adhesively attached to the skin offers a possible solution. The unattended approach may include delivering of multiple energies to enhance a visual appearance.

An osseointegrated fixture of a percutaneous osseointegrated prosthesis (POPs) anchors directly into a bone of a residual limb within an amputation stump. By anchoring directly into the bone, the POPs provides improved mobility, comfort, and function for an amputee, but an interface between an opening in the skin and the osseointegrated fixture, which allows the anchoring directly into the bone, is prone to infection by microbes. An anti-microbial device can be attached to and/or embedded within an extracorporeal portion of the osseointegrated fixture to irradiate at least a portion on the interface with at least one wavelength of light selected for its antimicrobial effects.

Dermatological systems and methods for providing a therapeutic laser treatment using a handpiece delivering one or more therapeutic laser pulses to a target skin area along a first optical path, and sensing the temperature of the target skin area based on infrared energy radiating from the target skin area along a second optical path generally counterdirectional to the first office action, and sharing a common optical axis with the first optical path for at least a portion of the first and second optical paths. The handpiece may also provide contact cooling for a first skin area comprising the target skin area.