An LED exterior luminaire comprising light-emitting diodes (LEDs) with a circadian-adjustable light output mode for its medical safety comprises at least two switchable LED chip chains I and III, wherein chain I comprising at least one LED chip emitting orange light from a wavelength range of 580 nm to 610 nm and at least one LED chip emitting red light from a wavelength range of 610 nm to 700 nm, chain III comprising at least one blue LED chip overlaid with a luminophore emitting a continuous band spectrum of visible light from a wavelength range of 440 nm to 700 nm and a correlated color temperature CCT of 2200 to 4200 K, wherein chains I and III are each separately connected to a power source via a dimming ballast that regulates the proportion of input current to each chain separately.

Lighting systems, methods, and devices for protecting human circadian neuroendocrine function during night use are described. Suitable lighting conditions can be provided for a working environment while protecting the circadian neuroendocrine systems of those occupying the illuminated workplace during the night. Lighting systems, methods, and devices can provide substantive attenuation of the pathologic circadian disruption in night workers. Lighting systems, methods, and devices can attenuate the specific bands of light implicated in circadian disruption. LED lighting systems, methods, and devices can provide increased intensity at a different portion of the spectrum than conventional LEDs, providing a useable white light even when unfavorable portions of the wavelength are attenuated by a notch filter. LED lighting systems, methods, and devices can switch between a daytime configuration and a night time configuration, wherein the daytime configuration provides unfiltered light and the night time configuration provides filtered light.

The invention relates to an irradiation apparatus for irradiating an irradiation object with light, comprising at least one light source with an identification unit that contains light source-specific information; a frame, more particularly a reflective frame, at least one light source holder on which the at least one light source is arranged by form-fitting insertion in the light source holder; and a region which provides a detection field of a communications device; the identification unit being positioned on the at least one light source such that the identification unit, by form-fitting insertion in the light source holder, is within the detection field.

An implantable light delivery device comprises: a core portion cladded in a cladding, the core portion comprising upconversion nano-particles (UCNPs) encapsulated in an encapsulation material. The implantable light delivery device may be used in treatments such as photodynamic therapy to provide an emission of light at a wavelength configured by the selection of UCNPs. The encapsulation material may comprise hydrogel and the cladding may comprise fluorinated ethylene propylene.

A method and a system for light-activated drug delivery. An optical probe is coupled to a tissue for transmitting light signals to the tissue for actuating and/or monitoring drug delivery with a multi-phase method for drug delivery. A first light signal is transmitted through the optical probe for actuating and/or monitoring the drug delivery and a second light signal having a different wavelength is transmitted, simultaneously with the first light signal, through the optical probe for actuating and/or monitoring the drug delivery.

A theranostic laser system for light-activated drug delivery and monitoring. The system includes a light source, a light receiver and a coupler for simultaneously coupling a first optical delivery fiber to the light source for transmitting one or more first downstream light signals from the light source to the first optical delivery fiber and to the light receiver for transmitting one or more first upstream light signals from the first optical delivery fiber to the light receiver.

Devices and related methods for impinging light on tissue to induce one or more biological effects, and more particularly illumination devices and related methods for phototherapeutic light treatments in the presence of vitamins are disclosed. Biological effects may include at least one of inactivating and inhibiting growth of one or more combinations of microorganisms and pathogens, including but not limited to viruses. Phototherapeutic light treatments in the presence of vitamins may involve providing one or more vitamins in the form of a coating or film on a surface of a target tissue and irradiating the target tissue with light. By performing the phototherapeutic light treatment in the presence of vitamins, efficacy of the light treatment may be improved, thereby reducing viral loads and/or reducing doses of light received by the target tissue.

Light administering device and methods of administering a dosage of light using the light administering device. The light administering device includes a light source configured to emit light rays and a collimating lens. The collimating lens is configured to collimate the light rays emitted from the light source such that the light rays are aligned in a light-emitting direction. The light administering device is configured to administering a dosage of light in the light-emitting direction towards the eyes of a user. The light administering device including may include plurality of light sources.

Light administering device and methods of administering a dosage of light using the light administering device. The light administering device includes a light source configured to emit light rays and a collimating lens. The collimating lens is configured to collimate the light rays emitted from the light source such that the light rays are aligned in a light-emitting direction. The light administering device is configured to administering a dosage of light in the light-emitting direction towards the eyes of a user. The light administering device including may include plurality of light sources.

The present disclosure presents infant soothing devices which provide timed, color, and intensity controlled light and sound projections to assist in sleep therapy. The devices may be part of a smart nursery which has a number of electronically connected devices which communicate with a central electronic application to gather information and provide operation instructions to the devices. The smart nursery may be connected to a larger network to provide feedback and controllability outside of the nursery.