The present invention relates to a two-component cosmetic composition for wrinkle reduction. The two-component cosmetic composition for wrinkle reduction according to the present invention forms a coating having a sufficient strength to reduce a scrubbing phenomenon caused by external force and has a suitable viscosity as well as no cloudiness phenomena arising.

The present invention relates to a two-component cosmetic composition for wrinkle reduction. The two-component cosmetic composition for wrinkle reduction according to the present invention forms a coating having a sufficient strength to reduce a scrubbing phenomenon caused by external force and has a suitable viscosity as well as no cloudiness phenomena arising.

A composition for external preparation for skin comprising the following components (A), (B), and (C):(A) from 0.1 to 30 mass % of a polymer having a silicone structure in which a ratio of deformation measured by a predetermined method (1) is 0.3 or more and 1 or less, and in a bend resistance test using a cylindrical mandrel method performed by a predetermined method (2), the minimum diameter of a cylindrical mandrel which causes no cracks in the polymer film is 2 mm or more and 25 mm or less; (B) a volatile oil having a volatilization rate of 14% or more after drying at 1 atmosphere, 40° C., and R.H. of 60% for 30 minutes; and (C) a non-volatile oil, wherein the mass ratio of the component (A) to the component (C), (A)/(C), is from 1 to 150.

A method of applying a skin peel formulation or product that includes providing a skin peel formulation or product containing at least 10% of the total weight of the skin peel formulation or product being vitamin A. Also provided is vitamin C present in at least 20% of the total weight of the skin peel formulation or product, wherein the vitamin C is in oil soluble form. The skin peel formulation is applied to a region of the body without any acid pre-treatments. After application of the skin peel formulation the user waits at least 25 days before reapplying the skin peel formulation again.

A method of applying a skin peel formulation or product that includes providing a skin peel formulation or product containing at least 10% of the total weight of the skin peel formulation or product being vitamin A. Also provided is vitamin C present in at least 20% of the total weight of the skin peel formulation or product, wherein the vitamin C is in oil soluble form. The skin peel formulation is applied to a region of the body without any acid pre-treatments. After application of the skin peel formulation the user waits at least 25 days before reapplying the skin peel formulation again.

The present disclosure relates to a composition comprising (20S,24R)-6-O-β-D-glucopyranosyl(1.fwdarw.2)-β-D-glucopyranoside-dammar-3-one-20,24-epoxy-6a,12b,25-triol, which is a novel ginsenoside, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof as an active ingredient. In addition, it relates to a method for improving skin elasticity or skin wrinkles, which comprises administering an effective amount of (20S,24R)-6-O-β-D-glucopyranosyl(1.fwdarw.2)-β-D-glucopyranoside-dammar-3-one-20,24-epoxy-6a,12b,25-triol, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof to a subject in need thereof. The novel ginsenoside, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof has a superior effect of improving skin elasticity and skin wrinkles.

The present disclosure relates to a composition comprising (20S,24R)-6-O-β-D-glucopyranosyl(1.fwdarw.2)-β-D-glucopyranoside-dammar-3-one-20,24-epoxy-6a,12b,25-triol, which is a novel ginsenoside, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof as an active ingredient. In addition, it relates to a method for improving skin elasticity or skin wrinkles, which comprises administering an effective amount of (20S,24R)-6-O-β-D-glucopyranosyl(1.fwdarw.2)-β-D-glucopyranoside-dammar-3-one-20,24-epoxy-6a,12b,25-triol, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof to a subject in need thereof. The novel ginsenoside, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof has a superior effect of improving skin elasticity and skin wrinkles.

A method of moisturizing skin of a person is disclosed. The method can include topically applying to the skin of the person a composition comprising an effective amount of an aqueous, alcoholic, or aqueous-alcoholic extract from Parkia biglobosa, wherein the composition moisturizes the skin.

A method of moisturizing skin of a person is disclosed. The method can include topically applying to the skin of the person a composition comprising an effective amount of an aqueous, alcoholic, or aqueous-alcoholic extract from Parkia biglobosa, wherein the composition moisturizes the skin.

The present invention relates to a skin administration system capable of improving the efficiency of skin delivery of an ingredient for controlling release of neurotransmitters and, particularly, to a microneedle containing an ingredient for controlling release of neurotransmitters.